14 completed, 2 active not recruiting, 2 recruiting, 2 unknown. 17 Not applicable, 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 17 | Completed 10, Active not recruiting 2, Recruiting 2, Unknown 2, Not yet recruiting 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
Follow Walnuts: new trials by email Literature Review of Walnuts trials Research Report on Walnuts
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of an Evening Snack of Walnuts on Diet and Sleep Quality in Adolescents Walnuts, Control (usual diet) - Diet Quality, Sleep | Not applicable | Not yet recruiting | Penn State University | 80 | 2027-01-01 | 2026-10-07 |
| Long-Term Effects of Walnut Consumption on Brain Function Walnuts - Healthy, Brain Insulin Sensitivity | Not applicable | Recruiting | Maastricht University Medical Center | 55 | 2025-10-01 | 2026-07-24 |
| Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults Walnuts, Crackers - Aging, Inflammation Biomarkers | Not applicable | Active not recruiting | Oregon State University | 90 | 2025-06-09 | 2026-08-07 |
| Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study Walnuts, Simply White Diary-free chocolate bar - Cognitive Decline, Cognitive Impairment | Not applicable | Recruiting | Ohio State University | 88 | 2024-02-07 | 2026-04-21 |
| Walnut and Immunity Study walnuts, Habitual diet - Immune Response, Upper Respiratory Tract Infection | Not applicable | Completed | Loma Linda University | 52 | 2023-06-27 | 2024-10-02 |
| Walnut Consumption and Gut Microbiota Walnuts, Walnut Oil, Control - Obesity, Inflammation | Not applicable | Unknown | University of Illinois at Urbana-Champaign | 30 | 2022-06-01 | 2023-06-18 |
| Response of Cardiometabolic Biomarkers and Gut Microbiota to Walnut Consumption Walnuts, No-nut diet - Cardiovascular Diseases | Not applicable | Active not recruiting | University of California, Davis | 30 | 2022-04-19 | 2026-02-10 |
| Walnuts and Colon Health (The WellNut Trial) Walnuts - Colorectal Cancer, Diet Habit | Not applicable | Completed | UConn Health | 140 | 2022-01-24 | 2026-10-05 |
| Analysis of Microbiota Variations in Industry Workers Working Different Shifts and Impact of a Nutritional Intervention Walnuts - Dysbiosis | Not applicable | Unknown | Sophie Bucher Della Torre | 18 | 2021-04-12 | 2022-05-16 |
| Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption Walnuts - Colo-rectal Cancer, Colon Cancer | Not applicable | Completed | UConn Health | 47 | 2019-05-20 | 2021-11-26 |
| WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy walnuts, usual diet, phone counseling with dietitian - Prostate Cancer | Phase 2 | Completed | Stephen Freedland | 52 | 2019-04-22 | 2026-10-06 |
| Walnuts to Achieve Lasting NUTrition to Prevent Diabetes Walnuts - PreDiabetes, Overweight and Obesity | Phase 1 / Phase 2 | Completed | University of California, San Francisco | 18 | 2018-05-21 | 2020-09-02 |
| Genotype, Metabotype and Diet in a Cohort of Children and Adolescents From the Southeast of Spain. Walnuts, Pomegranate juice - Genotype, Metabotype and Dietary Habits | Not applicable | Completed | National Research Council, Spain | 423 | 2016-02-01 | 2017-10-24 |
| The Metabolic Effect of Walnuts in Healthy Subjects walnuts - Lipid Metabolism Disorders | Not applicable | Completed | Ludwig-Maximilians - University of Munich | 180 | 2014-12-01 | 2017-08-29 |
| Nuts and Extra Virgin Olive Oil Pilot Study Walnuts, Extra Virgin Olive Oil - Hypertension | Not applicable | Completed | Wake Forest University Health Sciences | 27 | 2014-10-01 | 2018-08-01 |
| Effect of Walnuts on Sperm Parameters and Male Fertility Walnuts, OTC multivitamin - Oligozoospermia, Asthenozoospermia | Not applicable | Completed | University of California, Los Angeles | 80 | 2014-05-01 | 2026-03-13 |
| Walnuts and Healthy Aging Walnuts, habitual diet - Age Related Cognitive Decline, Age Related Macular Degeneration | Not applicable | Completed | Loma Linda University | 708 | 2012-04-01 | 2021-06-24 |
| Effects of the Consumption of California Walnuts on Cardiovascular Health Walnuts - Cardiovascular Health, Immune Function | Phase 1 | Completed | University of California, Davis | 36 | 2010-10-01 | 2013-11-04 |
| Effects of California Walnuts on Vascular Function in Postmenopausal Women Walnuts - Cardiovascular Diseases | Phase 1 | Completed | University of California, Davis | 5 | 2010-06-01 | 2010-11-01 |
| The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome Walnuts, Control - Metabolic Syndrome, Type 2 Diabetes | Not applicable | Completed | Christos Mantzoros | 40 | 2007-02-01 | 2017-12-15 |
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Cardiovascular Diseases (3) · Feeding Behavior (3) · Cognitive Dysfunction (2) · Colorectal Neoplasms (2) · Inflammation (2) · Obesity (2) · Asthenozoospermia (1) · Colitis (1) · Colonic Neoplasms (1) · Diabetes Mellitus, Type 2 (1) · Dysbiosis (1) · Hypertension (1) · Infertility, Male (1) · Insulin Resistance (1) · Lipid Metabolism Disorders (1)
University of California, Davis (4) · Loma Linda University (2) · UConn Health (2) · Christos Mantzoros (1) · Ludwig-Maximilians - University of Munich (1) · Maastricht University Medical Center (1) · National Research Council, Spain (1) · Ohio State University (1) · Oregon State University (1) · Penn State University (1) · Sophie Bucher Della Torre (1) · Stephen Freedland (1) · University of California, Los Angeles (1) · University of California, San Francisco (1) · University of Illinois at Urbana-Champaign (1)
United States (16) · Spain (2) · Germany (1) · Netherlands (1) · Switzerland (1)
Christian Jobin, Ph.D. (1) · Christos S Mantzoros, MD (1) · Daniel W. Rosenberg, Ph.D. (1) · Emilio Ros, MD, PhD (1) · Emily E Hohman, PhD (1) · Emily Ho, PhD (1) · Howard H Kim, MD (1) · Joan Sabate, MD, DrPH (1) · Juan C. Espin, PhD (1) · Klaus G Parhofer, MD (1) · Mara Z Vitolins, DrPH MPH RDN (1) · Martha Belury, PhD, RDN (1) · Meghana Gadgil, MD (1)
PMID 19910942, PMID 27535872, PMID 27636672, PMID 28119602, PMID 29478886, PMID 30879358, PMID 30962275, PMID 31912155, PMID 32428300, PMID 32827219, PMID 33017652, PMID 33236064, PMID 33903255, PMID 37365003, PMID 38081585, PMID 41418290, PMID 42373047, PMID 42841852
R01CA252045 (1), R21AT002280 (1)