5 unknown, 3 completed, 1 active not recruiting. 9 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Unknown 5, Completed 3, Active not recruiting 1 |
| Phase 3 | 3 | Unknown 2, Completed 1 |
| Phase 1 | 1 | Active not recruiting 1 |
Follow Vitamin K 2: new trials by email Literature Review of Vitamin K 2 trials Research Report on Vitamin K 2
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Role of Vitamin K on Knee Osteoarthritis Outcomes Vitamin K1 500 µg, K1 1000 µg, Vitamin K2 (MK-7) 300 µg - Osteo Arthritis Knee | Phase 1 / Phase 2 | Active not recruiting | Boston University | 49 | 2025-06-03 | 2026-09-21 |
| Comparative Study Evaluating the Effect of Vitamin K1 Versus Vitamin K2 on Vascular Calcification in Dialysis Patients Vitamin K1, Vitamin k2, placebo - End Stage Renal Disease on Dialysis | Phase 2 / Phase 3 | Completed | Ain Shams University | 40 | 2020-07-25 | 2021-07-21 |
| Effect of Vitamin K 2 on Vascular Calcification in Hemodialysis Patients Vitamin K2, Cholecalciferol (inactive vitamin D), Vitamin K2 and Cholecalciferol - End Stage Renal Disease | Phase 2 / Phase 3 | Unknown | Ain Shams University | 60 | 2019-09-01 | 2019-10-30 |
| Decalcification of the Aortic Valve by Vitamin K2 (Menaquinone-7) Vitamin K2 (Menaquinone 7) + Vitamin D3 - Aortic Valve Disease | Phase 2 | Unknown | Hopital St. Georges, Ajaltoun | 150 | 2018-01-02 | 2019-08-09 |
| Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI Vitamin K2, Placebo - Aortic Valve Stenosis, Bicuspid Aortic Valve | Phase 2 | Unknown | Maastricht University Medical Center | 44 | 2016-08-01 | 2018-03-22 |
| Vitamin K as Additive Treatment in Osteoporosis Phylloquinone, Menatetrenone (MK4), placebo - Post-menopausal Osteoporosis | Phase 2 / Phase 3 | Unknown | Guy's and St Thomas' NHS Foundation Trust | 105 | 2015-04-01 | 2020-02-13 |
| Vitamin K2 Supplementation and Arterial Stiffness in the Renal Transplant Population (The KING Trial) Vitamin K2 (MK7) - Arterial Stiffness, Vitamin K2 Deficiency | Phase 2 | Completed | Lebanese American University | 60 | 2015-03-01 | 2018-02-09 |
| Phase II Randomized Placebo-controlled Study With Vitamin K2 in Asymptomatic Calcified Carotid Stenosis Vitamin K2 (Menaquinone) - Carotid Disease, Atherosclerosis | Phase 2 | Unknown | Azienda Ospedaliera Sant'Anna | 200 | 2013-09-01 | 2014-05-28 |
| Vitamin K2 Intervention in Patients With Vitamin K Antagonists Vitamin K2 - Thrombosis | Phase 2 | Completed | Danisco | 50 | 2012-02-01 | 2014-04-08 |
Aortic Valve Disease (1) · Aortic Valve Stenosis (1) · Atherosclerosis (1) · Bicuspid Aortic Valve Disease (1) · Kidney Failure, Chronic (1) · Osteoporosis (1) · Osteoporosis, Postmenopausal (1) · Thrombosis (1)
Ain Shams University (2) · Azienda Ospedaliera Sant'Anna (1) · Boston University (1) · Danisco (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Hopital St. Georges, Ajaltoun (1) · Lebanese American University (1) · Maastricht University Medical Center (1)
Egypt (2) · Lebanon (2) · France (1) · Netherlands (1) · United Kingdom (1) · United States (1)
Bas Kietselaer, M.D. PhD (1) · Geeta Hampson, MD (1) · Jean Liew, MD MS (1) · Kirsti Tiihonen, PhD (1) · Ludovic Drouet, Professor (1) · Sola Aoun Bahous, M.D. Ph.D. (1)
K23AR082938 (1)