11 completed, 5 unknown, 3 terminated, 2 active not recruiting. 14 Not applicable, 4 Phase 3, 3 Phase 4, 1 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension. Norepinephrine, Phenylephrine - Outcome | Not applicable | Completed | General Hospital of Ningxia Medical University | 700 | 2025-08-01 | 2026-04-28 |
| ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients Norepinephrine, Phenylephrine - Adverse Effect | Not applicable | Unknown | General Hospital of Ningxia Medical University | 80 | 2025-07-01 | 2023-12-06 |
| ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment Norepinephrine, Phenylephrine - Adverse Effect | Not applicable | Unknown | General Hospital of Ningxia Medical University | 80 | 2025-04-01 | 2023-12-06 |
| ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment Norepinephrine, Phenylephrine - Adverse Effect | Not applicable | Completed | General Hospital of Ningxia Medical University | 60 | 2025-01-01 | 2025-05-25 |
| ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients Norepinephrine, Phenylephrine - Adverse Effect | Not applicable | Completed | General Hospital of Ningxia Medical University | 60 | 2024-10-03 | 2025-10-06 |
| A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia Ephedrine-P, Phenylephrine-P, Norepinephrine-P - Hypotension Drug-Induced | Phase 4 | Recruiting | Dalian Municipal Central Hospital | 180 | 2024-03-05 | 2024-11-06 |
| Shock and Acute Conditions OutcOmes Platform Inotrope, Mechanical circulatory support, anti-bodies - Circulatory Shock, Sepsis | Unknown | Saint-Louis Hospital, Paris, France | 1000 | 2024-01-01 | 2024-04-19 | |
| Prophylactic Norepinephrine Infusion Combined With Colloid Coloading for Postspinal Anesthesia Hypotension Normal saline, Norepinephrine (0.025 μg/kg/min), Norepinephrine (0.05 μg/kg/min) - Adverse Event | Not applicable | Completed | General Hospital of Ningxia Medical University | 175 | 2021-11-26 | 2022-09-07 |
| Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis Vasopressor, Fluids - Shock, Septic | Phase 3 | Active not recruiting | Australian and New Zealand Intensive Care Research Centre | 1000 | 2021-10-26 | 2026-03-17 |
| No Monitoring of Post-filter Ionized Calcium in Regional Citrate Anticoagulation Regional citrate anticoagulation, Vasopressor, Antibiotic - Regional Citrate Anticoagulation, Ionized Calcium | Not applicable | Completed | Chulalongkorn University | 50 | 2021-04-01 | 2022-11-14 |
| Norepinephrine and Phenylephrine, Which Better for Elderly? norepinephrine, Phenylephrine - Hypotension | Phase 3 | Unknown | The Second Affiliated Hospital of Dalian Medical University | 100 | 2019-10-06 | 2019-10-08 |
| Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) System Phenylephrine, Ephedrine, ADIVA System - Hypotension, Anesthesia | Not applicable | Active not recruiting | KK Women's and Children's Hospital | 173 | 2018-11-07 | 2026-08-14 |
| Cardiogenic Shock Working Group Registry Vasopressor, Inotrope, Acute Mechanical Circulatory Support Devices - Cardiogenic Shock | Recruiting | Tufts Medical Center | 5000 | 2017-12-04 | 2025-06-06 | |
| The Randomized Controlled Trial of Inferior Vena Cava Ultrasound-guided Fluid Management in Septic Shock Resuscitation IVC Ultrasound-guided, Antibiotics, Vasopressor - Septic Shock | Not applicable | Completed | Chulalongkorn University | 211 | 2017-01-18 | 2021-09-22 |
| Changes in Measured Plasma Volume, Glycocalyx and Atrial Natriuretic Peptide During Anaesthesia Norepinephrine, Maintained blood pressure - Blood Pressure, Anesthesia | Not applicable | Completed | Sahlgrenska University Hospital | 24 | 2016-10-01 | 2020-04-30 |
| Phenylephrine or Norepinephrine for a Better Hemodynamic Stability phenylephrine, Norepinephrine - Hypotension, Fluid Therapy | Phase 3 | Completed | The Second Affiliated Hospital of Dalian Medical University | 40 | 2016-09-01 | 2018-01-23 |
| Perioperative Fluid Management in Patients Receiving Major Abdominal Surgery - Effects of Normal Saline Versus an Acetate Buffered Balanced Infusion Solution on the Necessity of Catecholamines for Cardiocirculatory Support vasopressor, fluid bolus, oesophagus doppler (CardioQ) - Critical Illness | Phase 4 | Terminated | Medical University of Vienna | 60 | 2015-03-01 | 2016-05-02 |
| Pressure-dependent Changes in Hematocrit and Plasma Volume During Anesthesia Maintained blood pressure, Norepinephrine - Blood Pressure, Hematocrit Change | Not applicable | Unknown | Sahlgrenska University Hospital | 24 | 2014-02-01 | 2015-04-09 |
| A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability vasopressor delivery automated system, phenylephrine, ephedrine - Hypotension | Phase 2 / Phase 3 | Completed | KK Women's and Children's Hospital | 252 | 2013-05-01 | 2026-08-07 |
| Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock epinephrine perfusion, norepinephrine perfusion - Cardiogenic Shock | Phase 4 | Completed | Central Hospital, Nancy, France | 58 | 2011-09-01 | 2019-02-01 |
Showing 20 of 23. Sign in to see all of them.
Hypotension (5) · Shock, Cardiogenic (3) · Emergencies (2) · Sepsis (2) · Shock (2) · Shock, Septic (2) · Critical Illness (1) · Heart Failure (1) · Myocardial Infarction (1) · Postoperative Complications (1) · Shock, Surgical (1) · Thrombosis (1) · Wounds and Injuries (1)
General Hospital of Ningxia Medical University (6) · Chulalongkorn University (2) · KK Women's and Children's Hospital (2) · Sahlgrenska University Hospital (2) · The Second Affiliated Hospital of Dalian Medical University (2) · University Hospital, Geneva (2) · Australian and New Zealand Intensive Care Research Centre (1) · Central Hospital, Nancy, France (1) · Dalian Municipal Central Hospital (1) · Domonkos Trásy (1) · Medical University of Vienna (1) · Saint-Louis Hospital, Paris, France (1) · Tufts Medical Center (1)
China (6) · Singapore (2) · Sweden (2) · Switzerland (2) · Thailand (2) · Australia (1) · Austria (1) · Canada (1) · France (1) · Hungary (1) · Ireland (1) · New Zealand (1) · United States (1)
Yi Chen, M.D. (6) · Andreas Nygren, MD PHD (2) · Alexandre Mebazaa, MD, PhD (1) · Ban L Sng, FANZCA (1) · Claudia dos Santos, MD, PhD (1) · Claudius Mahr, DO (1) · Daniel Burkhoff, MD PhD (1) · Gordana Pavlovic, MD (1) · Hong Fang, MD (1) · Jaime Hernandez-Montfort, MD (1) · Khrongwong Musikatavorn, MD (1) · Klaus Markstaller, MD (1) · Reshad Garan, MD (1) · Sandra Peake, MBBS (1)
PMID 26041437, PMID 29373334, PMID 29406176, PMID 29976291, PMID 31472039, PMID 32280413, PMID 32352638, PMID 32473083, PMID 32487943, PMID 32765837, PMID 32900234, PMID 33005634, PMID 33121702, PMID 33831901, PMID 34101716, PMID 35835491, PMID 36342421, PMID 36703120, PMID 37664560, PMID 37812381, PMID 39802301, PMID 40685240, PMID 41200476, PMID 42137315, PMID 42274006
2009 (1)