11 completed, 4 unknown, 2 terminated, 1 temporarily not available. 7 Phase 4, 5 Phase 2, 3 Phase 1, 2 Phase 3, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Unknown 4, Completed 3 |
| Phase 2 | 5 | Completed 4, Terminated 1 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 2 | Completed 2 |
| Early Phase 1 | 1 | Terminated 1 |
Follow Vardenafil: new trials by email Literature Review of Vardenafil trials Research Report on Vardenafil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vardenafil Vs Sildenafil for the Treatment of Pulmonary Hypertension of the Newborn Vardenafil, Sildenafil - PPHN | Phase 1 / Phase 2 | Completed | Damascus University | 55 | 2023-05-01 | 2025-03-06 |
| Effect of Vardenafil on Erectile Dysfunction and Portal Hemodynamics in Patients With Liver Cirrhosis Vardenafil, HVPG (Hepatic venous pressure measurement) baseline, HVPG (Hepatic venous pressure measurement) day 7 - Cirrhosis, Erectile Dysfunction | Phase 4 | Unknown | Medical University of Vienna | 30 | 2012-06-01 | 2015-09-25 |
| Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases Vardenafil, Carboplatin - Glioma, Brain Neoplasms | Early Phase 1 | Terminated | Cedars-Sinai Medical Center | 7 | 2012-03-27 | 2017-09-11 |
| Vardenafil and Cognitive-behavioral Sex Therapy for the Treatment of Erectile Dysfunction (STEDOV) Vardenafil, CBST - Erectile Dysfunction | Phase 4 | Completed | University of Florence | 30 | 2012-03-01 | 2018-10-16 |
| Does a Nasal Instillation of Vardenafil Normalize the Nasal Potential Difference in Cystic Fibrosis Patients? Vardenafil, Placebo - Cystic Fibrosis | Phase 2 | Terminated | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 5 | 2011-10-01 | 2019-02-25 |
| The Safety of Vardenafil in Patients Undergoing Cardiac Surgery Vardenafil - Ischemia-reperfusion Injury. | Phase 1 | Completed | McGuire Research Institute | 10 | 2010-12-01 | 2011-11-04 |
| Clinical Proof-of-concept Study for the Combination BAY60-4552 / Vardenafil for the Treatment of Erectile Dysfunction Not Sufficiently Responsive to Standard Therapy With PDE5 Inhibitors BAY60-4552 plus Vardenafil, Vardenafil, Placebo - Erectile Dysfunction | Phase 2 | Completed | Bayer | 140 | 2010-08-01 | 2014-11-04 |
| A Study to Determine if There is a Possible Association Between NAION and Phosphodiesterase Type 5 (PDE5) Inhibitors PDE5 Inhibitors - Nonarteritic Anterior Ischemic Optic Neuropathy | Completed | Eli Lilly and Company | 345 | 2010-05-01 | 2018-04-05 | |
| Diabetes & Vardenafil Vardenafil, Placebo - Type 2 Diabetes Mellitus (T2DM), Endothelial Dysfunction | Phase 2 | Completed | Azienda USL Modena | 54 | 2010-03-01 | 2014-08-19 |
| Correlation Study of Vascular Parameters in Hypertensive Men With Erectile Dysfunction Vardenafil - Erectile Dysfunction, Arterial Hypertension | Phase 4 | Completed | Hospital Universitario Pedro Ernesto | 100 | 2010-01-01 | 2011-04-18 |
| Long Acting Phosphodiesterase 5 Inhibitors as Add-on Therapy for Patients With Pulmonary Hypertension Treated With Prostanoids. Tadalafil, Vardenafil - Pulmonary Arterial Hypertension | Phase 4 | Unknown | Rabin Medical Center | 30 | 2008-08-01 | 2008-06-26 |
| A Study to Evaluate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction Caused by Spinal Cord Injury Vardenafil, Placebo - Erectile Dysfunction | Phase 4 | Unknown | China Rehabilitation Research Center | 350 | 2008-08-01 | 2008-07-30 |
| The Efficacy and Safety of Vardenafil in the Treatment of Pulmonary Arterial Hypertension Vardenafil, Placebo - Pulmonary Hypertension | Phase 3 | Completed | Tongji University | 60 | 2008-07-01 | 2010-02-12 |
| Study To Investigate The Hemodynamic Effects Of Single Dose Vardenafil In Subjects Receiving Maraviroc Maraviroc, Vardenafil, Placebo - AIDS | Phase 4 | Completed | ViiV Healthcare | 18 | 2008-04-01 | 2013-01-25 |
| The Effect of CYP3A Genetic Polymorphism on the Pharmacokinetics of Phosphodiesterase type5 Inhibitors in Male Subjects phosphodiesterase type 5 inhibitor - Pharmacokinetics of Three PDE5Is, Healthy Subjects | Phase 1 | Completed | Inje University | 21 | 2007-12-01 | 2008-10-07 |
| Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i Sildenafil, Vardenafil, Sildenafil, Vardenafil - Impotence | Phase 4 | Unknown | Rambam Health Care Campus | 46 | 2007-03-01 | 2010-10-22 |
| Effects of Vardenafil on Clinical Symptoms and Peripheral Blood Flow in Patients With Raynaud's Syndrome vardenafil, Placebo - Raynaud Syndrome | Phase 2 / Phase 3 | Completed | University of Cologne | 57 | 2006-11-01 | 2011-02-08 |
| Improvement of Myocardial Blood Flow by PhosphoDiesterase 5 Inhibition in Coronary Artery Disease Vardenafil, Placebo - Therapy Refractory Myocardial Ischemia, Coronary Artery Disease | Temporarily not available | Medical University of Vienna | 2011-08-01 |
Erectile Dysfunction (7) · Acquired Immunodeficiency Syndrome (1) · Brain Neoplasms (1) · Coronary Artery Disease (1) · Cystic Fibrosis (1) · Diabetes Mellitus, Type 2 (1) · Fibrosis (1) · Glioma (1) · Hypertension (1) · Hypertension, Portal (1) · Hypertension, Pulmonary (1) · Optic Neuropathy, Ischemic (1) · Pulmonary Arterial Hypertension (1) · Raynaud Disease (1) · Reperfusion Injury (1)
Medical University of Vienna (2) · Azienda USL Modena (1) · Bayer (1) · Cedars-Sinai Medical Center (1) · China Rehabilitation Research Center (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Damascus University (1) · Eli Lilly and Company (1) · Hospital Universitario Pedro Ernesto (1) · Inje University (1) · McGuire Research Institute (1) · Rabin Medical Center (1) · Rambam Health Care Campus (1) · Tongji University (1) · University of Cologne (1)
Italy (3) · United States (3) · Austria (2) · Belgium (2) · China (2) · Germany (2) · Israel (2) · Brazil (1) · Finland (1) · France (1) · Netherlands (1) · Spain (1) · Sweden (1) · Syria (1)
Arnulf Ferlitsch, MD (1) · Ilan Gruenwald, MD (1) · Ion Jovin, MD (1) · Jae-Gook Shin (1) · Li-Min Liao, Dr. (1) · Manuela Simoni, MD, PhD (1) · Mario F Neves, MD, PhD. (1) · Mario Maggi (1) · Mordechai R Kramer, MD (1) · Stephan Rosenkranz, MD (1)
PMID 15618584, PMID 18006891, PMID 26311340
2005 (1)