5 completed, 3 unknown. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 5, Unknown 3 |
Follow Tropisetron: new trials by email Literature Review of Tropisetron trials Research Report on Tropisetron
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Three Antiemetics in Preventing Nausea and Vomiting tropisetron, metoclopramide, dexamethasone - Nausea and Vomiting | Phase 4 | Completed | The Second Affiliated Hospital of Chongqing Medical University | 200 | 2022-09-15 | 2024-04-02 |
| Effect of Glycopyrronium in Combination With Tropisetron in Anti-postoperative Nausea and Vomiting Glycopyrronium in Combination With Tropisetron, Normal Saline in Combination With Tropisetron - Postoperative Nausea and Vomiting | Phase 4 | Completed | The Second Affiliated Hospital of Chongqing Medical University | 480 | 2022-04-21 | 2024-08-16 |
| Oral Akynzeo® vs Standard of Care in Preventing CINV in High-risk MEC Patients (MyRisk) NEPA (300mg netupitant/0.5mg palonosetron), Granisetron, 2 mg (oral) or 1 mg (IV) OR Palonosetron, 0.5 mg (oral), 0.25mg (IV) OR Ondansetron, 16 mg (oral) or 8 mg (IV) OR Dolasetron 100 mg (oral) OR Tropisetron 5 mg (oral or IV), Dexamethasone, 8 mg (oral) or equivalent IV dose - Chemotherapy-induced Nausea and Vomiting | Phase 4 | Completed | Helsinn Healthcare SA | 414 | 2021-02-01 | 2025-12-02 |
| A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surgery Tropisetron, Placebos - Postoperative Cognitive Dysfunction, Postoperative Delirium | Phase 4 | Unknown | Beijing Chao Yang Hospital | 72 | 2020-11-01 | 2022-01-05 |
| The Efficacy and Safety of Tropisetron in Preventing Emergence Delirium Tropisetron, Placebos - Emergence Delirium, Postoperative Delirium | Phase 4 | Unknown | Beijing Chao Yang Hospital | 1508 | 2019-08-01 | 2020-03-11 |
| A Study Evaluating the Efficacy and Safety of Aprepitant in Autologous Hematopoietic Stem Cell Transplantation Tropisetron, Dexamethasone, Aprepitant - Vomiting | Phase 4 | Unknown | Jun Zhu | 130 | 2015-10-01 | 2016-12-30 |
| A Korean Study of Efficacy and Safety of Aprepitant-based Triple Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapy (Non-doxorubicin Hydrochloride [Adriamycin] and Cyclophosphamide Regimens) (MK-0869-225) (KMEC) Aprepitant, Aprepitant Placebo, Ondansetron - Nausea, Vomiting | Phase 4 | Completed | Merck Sharp & Dohme LLC | 494 | 2012-12-12 | 2018-09-25 |
| Clinical Confirmation of a Pharmacodynamic Interaction Between Tropisetron and Paracetamol Tropisetron, paracetamol - Pain | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 40 | 2008-06-01 | 2010-03-29 |
Vomiting (4) · Emergence Delirium (2) · Nausea (2) · Hematologic Neoplasms (1) · Lymphoma (1) · Neoplasms (1) · Pain (1) · Postoperative Cognitive Complications (1) · Postoperative Nausea and Vomiting (1)
Beijing Chao Yang Hospital (2) · The Second Affiliated Hospital of Chongqing Medical University (2) · Helsinn Healthcare SA (1) · Jun Zhu (1) · Merck Sharp & Dohme LLC (1) · University Hospital, Clermont-Ferrand (1)
China (5) · Czechia (1) · France (1) · Germany (1) · Greece (1) · Spain (1) · Switzerland (1) · United Kingdom (1)
Alex Molasiotis, prof. (1) · Guangyou Duan, MD (1) · He Huang, MD (1) · Jun Zhu, MD (1) · Pickering Gisele, MCU-PH (1)