14 completed, 3 recruiting, 2 withdrawn, 1 unknown. 20 Phase 2, 4 Phase 1, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Completed 14, Recruiting 3, Withdrawn 2, Unknown 1 |
| Phase 1 | 4 | Recruiting 3, Completed 1 |
| Phase 3 | 4 | Completed 4 |
Follow Transdermal Patch: new trials by email Literature Review of Transdermal Patch trials Research Report on Transdermal Patch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Valproate for the Treatment of Residual Amblyopia Valproate, Placebo, Patch - Amblyopia, Amblyopia Unilateral | Phase 1 / Phase 2 | Recruiting | Boston Children's Hospital | 28 | 2026-07-01 | 2026-07-30 |
| Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome Capsaicin 8% Patch, Serratus Plane Block, Botulinum Toxin A - Post-Mastectomy Neuropathic Pain Syndrome | Phase 2 | Withdrawn | Centre Oscar Lambret | 2025-06-10 | 2026-10-06 | |
| Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1 of 3) Combination Nicotine Replacement Therapy (patch and lozenge) - Remote vs. In-Person, Remote Visits | Phase 2 / Phase 3 | Completed | State University of New York at Buffalo | 200 | 2025-03-10 | 2026-11-05 |
| Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting Lignocaine-loaded maltose microneedle array patch, EMLA 5% patch - Glaucoma, Cataract | Phase 1 / Phase 2 | Recruiting | Universiti Kebangsaan Malaysia Medical Centre | 154 | 2025-02-17 | 2025-07-18 |
| Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC) Microneedle Array Doxorubicin (MNA-D) - Cutaneous Squamous Cell Carcinoma, Skin Cancers - Squamous Cell Carcinoma | Phase 1 / Phase 2 | Recruiting | Falo, Louis, MD | 48 | 2023-09-13 | 2026-04-09 |
| Transgender Estradiol Affirming Therapy Transdermal patch, Pro-thrombotic markers, Metabolic markers - Transgenderism | Phase 2 | Completed | Washington University School of Medicine | 39 | 2021-08-02 | 2024-11-26 |
| Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers D-cycloserine, Nicotine Replacement Therapy (patch), Smoking Cue Exposure - Cigarette Smoking | Phase 2 | Withdrawn | New York State Psychiatric Institute | 2013-08-01 | 2020-10-08 | |
| Study to Evaluate Pharmacokinetics Profile, Wearability, and Safety of 2 Progestin-Only Patches levonorgestrel - Healthy | Phase 1 / Phase 2 | Completed | Agile Therapeutics | 36 | 2012-07-01 | 2018-01-23 |
| Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome Synera® (lidocaine 70 mg and tetracaine 70 mg) topical patch, Triamcinolone Acetonide - Shoulder Pain | Phase 2 | Unknown | Injury Care Medical Center | 60 | 2012-03-01 | 2012-03-06 |
| Oleogel-S10 in Wound Healing of Inherited Epidermolysis Bullosa (BEB-10) Oleogel-S10, Mepilex® soft silicone faced polyurethane foam dressing - Inherited Epidermolysis Bullosa | Phase 2 | Completed | Birken AG | 10 | 2010-11-01 | 2018-01-23 |
| Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy Skin biopsy, Lidocaine 5% patches - Diabetic Peripheral Neuropathy | Phase 2 / Phase 3 | Completed | Albany Medical College | 51 | 2009-10-01 | 2020-06-11 |
| Open-Label Study Evaluating Synera® in the Treatment of Patients With Carpal Tunnel Syndrome Synera (lidocaine 70 mg and tetracaine 70 mg) topical patch - Carpal Tunnel Syndrome | Phase 2 | Completed | ZARS Pharma Inc. | 24 | 2009-09-01 | 2012-03-16 |
| Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis Ketotifen 4.0% Patch, Placebo, Olopatadine 0.2% - Allergic Conjunctivitis | Phase 2 | Completed | Senju USA, Inc. | 122 | 2009-02-01 | 2023-08-04 |
| Study of Specific Allergen Immunotherapy in Grass Pollen Allergic Subjects With Epicutanoeus Allergen Administration Patch, Placebo patch - Allergic Rhinoconjunctivitis | Phase 2 | Completed | University of Zurich | 97 | 2008-10-01 | 2011-02-01 |
| A Dose-Finding Study of Fentanyl (JNS020 QD) 1-Day Transdermal Patch in Participants With Cancer Pain Fentanyl 1-day transdermal patch (Titration Phase), Fentanyl 1-day transdermal patch (Double Blind Phase), Fentanyl 3-day transdermal patch (Double Blind Phase) - Pain, Cancer | Phase 2 / Phase 3 | Completed | Janssen Pharmaceutical K.K. | 156 | 2007-12-01 | 2013-06-13 |
| Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee Lidoderm (Lidocaine 5% Patch), Placebo Patch - Osteoarthritis of the Knee | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 169 | 2007-03-01 | 2017-10-05 |
| Study of a Bupivacaine Patch (Eladur™) to Treat Post- Herpetic Neuralgia Transdermal/Patch (Bupivacaine TTS [Eladur™]) - Postherpetic Neuralgia, Pain | Phase 2 | Completed | Durect | 60 | 2006-09-01 | 2009-09-11 |
| Pilot Study of Lidocaine 5% Patch Versus Placebo in Patients With Osteoarthritis Pain of the Knee Lidoderm, Placebo patch - Osteoarthritis, Knee | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 224 | 2004-08-01 | 2010-02-10 |
| A Study Comparing The Efficacy And Safety Of Lidocaine 5% Patch With Placebo In Patients With Chronic Axial Low Back Pain Lidoderm®, Placebo Topical Patch - Chronic Low Back Pain | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 215 | 2004-08-01 | 2013-12-06 |
| Testosterone Replacement Therapy in Chronic Spinal Cord Injury Testosterone Transdermal System (Androderm 5 mg patch) - Spinal Cord Injury, Hypogonadism | Phase 2 / Phase 3 | Completed | VA Office of Research and Development | 31 | 2003-08-01 | 2017-11-01 |
Pain (3) · Osteoarthritis, Knee (2) · Agnosia (1) · Amblyopia (1) · Breast Neoplasms (1) · Carpal Tunnel Syndrome (1) · Cataract (1) · Cigarette Smoking (1) · Conjunctivitis, Allergic (1) · Epidermolysis Bullosa (1) · Eye Diseases (1) · Glaucoma (1) · Herpes Zoster (1) · Hypogonadism (1) · Neoplasms (1)
Endo USA Inc., a Keenova Therapeutics Company (3) · Agile Therapeutics (1) · Albany Medical College (1) · Birken AG (1) · Boston Children's Hospital (1) · Centre Oscar Lambret (1) · Durect (1) · Falo, Louis, MD (1) · Injury Care Medical Center (1) · Janssen Pharmaceutical K.K. (1) · New York State Psychiatric Institute (1) · Senju USA, Inc. (1) · State University of New York at Buffalo (1) · Universiti Kebangsaan Malaysia Medical Centre (1) · University of Zurich (1)
United States (14) · France (1) · Germany (1) · Japan (1) · Malaysia (1) · Switzerland (1)
Agnes Schwieger-Briel, MD (1) · Elizabeth Garner, MD, PHD (1) · Eric D Gaier, MD, PhD (1) · Ernest A. Kopecky, PhD, MBA (1) · Gail Torkildsen, MD (1) · Ginger Nicol, MD (1) · Oleg E Akilov, MD, PhD (1) · Richard D Radnovich, DO (1) · S. Rob Vorel, MD, PhD (1)
PMID 21252493, PMID 21717386, PMID 23343764, PMID 24968251, PMID 38133914, PMID 42947186
P50CA254865 (1), UH3TR004797 (1)