6 completed, 4 unknown, 3 terminated, 1 recruiting. 15 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 15 | Completed 6, Unknown 4, Terminated 3, Recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Toremifene: new trials by email Literature Review of Toremifene trials Research Report on Toremifene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01) Fluzoparib, Anastrozole, Letrozole - Breast Cancer | Phase 3 | Recruiting | Fudan University | 766 | 2023-06-01 | 2024-02-08 |
| Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer Tamoxifen, Toremifene - Breast Cancer Female | Phase 3 | Unknown | Chinese Anti-Cancer Association | 844 | 2017-11-01 | 2017-11-22 |
| Adjuvant Toremifene With or Without Goserrelin in Premenopausal Women With Stage I-IIIA, Hormonal Receptor Positive Breast Cancer Accompanied With or Without Chemotherapy Induced Amenorrhoea Goserelin, Toremifene - Breast Cancer, Chemotherapy Induced Amenorrhea | Phase 3 | Unknown | Peking Union Medical College Hospital | 300 | 2014-05-01 | 2014-06-04 |
| Efficacy and Tolerability of Toremifene or Tamoxifen Therapy in Premenopausal Estrogen and Progesterone Receptor Positive Breast Cancer Patients toremifene or tamoxifen - Breast Cancer Patients in Premenopausal, Estrogen and/or Progesterone Receptor Positive | Phase 2 / Phase 3 | Unknown | Fengxi Su | 3036 | 2014-04-01 | 2014-05-06 |
| Prognostic Evaluation of Changing Endocrine Therapy in Women With Breast Cancer Anastrozole, Tamoxifen, Toremifene - Breast Cancer | Phase 3 | Unknown | Peking Union Medical College Hospital | 600 | 2014-03-01 | 2016-05-25 |
| Efficacy and Safety Study of Toremifene Citrate for the Reduction in the Risk of New Bone Fracture Occurrences in Men With Prostate Cancer Toremifene - Risk of Bone Fracture Occurrences | Phase 3 | Withdrawn | GTx | 2011-03-01 | 2013-11-15 | |
| Changes in Breast 3D Ultrasound Measurements Using Toremifene Toremifene - Circulatory; Change | Phase 3 | Completed | Satakunta Central Hospital | 20 | 2010-09-01 | 2011-08-23 |
| The Effect of Toremifene Treatment to the Magnetic Resonance Imaging (MRI) Findings in Premenstrual Mastalgia toremifene, placebo - Breast Pain | Phase 3 | Completed | Satakunta Central Hospital | 10 | 2007-04-01 | 2009-05-13 |
| Treatment and Survival Continuation Study of Atamestane Plus Toremifene vs Letrozole in Advanced Breast Cancer Atamestane, toremifene, letrozole - Breast Neoplasms, Neoplasms, Hormone-Dependent | Phase 3 | Terminated | Intarcia Therapeutics | 200 | 2005-11-01 | 2007-09-10 |
| Prostate Cancer Prevention Study for Men With High Grade PIN (Prostatic Intraepithelial Neoplasia) Toremifene 20 mg, Placebo - Preneoplastic Conditions, Prostatic Intraepithelial Neoplasia | Phase 3 | Completed | GTx | 1589 | 2005-01-01 | 2023-06-12 |
| The CAT Study: Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer Atamestane, Toremifene, Letrozole - Breast Neoplasms, Neoplasms, Hormone-Dependent | Phase 3 | Terminated | Intarcia Therapeutics | 842 | 2004-12-01 | 2007-08-23 |
| Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy Toremifene Citrate - Prostate Cancer, Osteoporosis | Phase 3 | Completed | GTx | 1200 | 2003-10-01 | 2013-11-15 |
| Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer atamestane, toremifene, letrozole - Breast Neoplasms, Neoplasms, Hormone-dependent | Phase 3 | Completed | Intarcia Therapeutics | 865 | 2002-06-01 | 2015-07-31 |
| Toremifene With or Without Atamestane in Treating Postmenopausal Women With Metastatic Breast Cancer atamestane, toremifene - Breast Cancer | Phase 3 | Terminated | Intarcia Therapeutics | 2000-10-01 | 2014-03-26 | |
| Hormone Therapy and Chemotherapy in Treating Perimenopausal or Postmenopausal Women With Node-Positive Breast Cancer cyclophosphamide, doxorubicin hydrochloride, epirubicin hydrochloride - Breast Cancer | Phase 3 | Completed | ETOP IBCSG Partners Foundation | 452 | 1993-05-01 | 2013-04-04 |
Breast Neoplasms (9) · Carcinoma, Ductal, Breast (3) · Carcinoma, Lobular (3) · Neoplasms, Hormone-Dependent (3) · Fractures, Bone (2) · Prostatic Neoplasms (2) · Bone Diseases, Metabolic (1) · Mastodynia (1) · Neoplasms (1) · Osteoporosis (1) · Precancerous Conditions (1) · Premenstrual Syndrome (1) · Prostatic Intraepithelial Neoplasia (1)
Intarcia Therapeutics (4) · GTx (3) · Peking Union Medical College Hospital (2) · Satakunta Central Hospital (2) · Chinese Anti-Cancer Association (1) · ETOP IBCSG Partners Foundation (1) · Fengxi Su (1) · Fudan University (1)
United States (7) · China (5) · Canada (3) · Russia (3) · Ukraine (3) · Finland (2) · Argentina (1) · Australia (1) · Bulgaria (1) · Italy (1) · Mexico (1) · New Zealand (1) · Romania (1) · Slovenia (1) · South Africa (1)
Peter Langecker, MD, PhD (2) · Edda Simoncini, MD (1) · Edith Perez, MD (1) · Mitchell Steiner, M.D. (1) · Mitchell Steiner, MD (1) · Paul Goss, M.D. (1) · Qiang Sun, Doctor (1) · Samir Taneja, MD (1) · Sinikka Oksa, MD (1) · Zhimin Shao, Master (1)