3 completed, 3 unknown, 2 withdrawn, 1 recruiting. 10 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 3, Unknown 3, Withdrawn 2, Recruiting 1, Terminated 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Toremifene: new trials by email Literature Review of Toremifene trials Research Report on Toremifene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy Accelerated Partial Breast Irradiation (APBI), tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene - Breast Cancer, Quality of Life | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 90 | 2022-05-17 | 2026-05-26 |
| Selective Estrogen Modulation and Melatonin in Early COVID-19 Toremifene, Melatonin, Placebo - Covid19 | Phase 2 | Withdrawn | Reena Mehra, MD | 2021-12-01 | 2021-05-10 | |
| Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer metformin, Melatonin, Toremifene - Breast Cancer | Phase 2 | Unknown | N.N. Petrov National Medical Research Center of Oncology | 96 | 2015-07-01 | 2019-09-04 |
| Efficacy and Tolerability of Toremifene or Tamoxifen Therapy in Premenopausal Estrogen and Progesterone Receptor Positive Breast Cancer Patients toremifene or tamoxifen - Breast Cancer Patients in Premenopausal, Estrogen and/or Progesterone Receptor Positive | Phase 2 / Phase 3 | Unknown | Fengxi Su | 3036 | 2014-04-01 | 2014-05-06 |
| Toremifene in Desmoid Tumor: Prospective Clinical Trial and Identification of Potential Molecular Targets Toremifene - Desmoid Type-fibromatosis | Phase 2 | Unknown | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 25 | 2012-11-01 | 2015-02-02 |
| Antiestrogen vs Aromatase Inhibitor After Adjuvant Chemotherapy for Breast Cancer Toremifene citrate, Anastrozole - Breast Neoplasms | Phase 2 | Terminated | Japan Breast Cancer Research Network | 240 | 2007-05-01 | 2012-03-30 |
| A Chemoprevention Study of an Investigational Drug in Men With High Grade Prostate Intraepithelial Neoplasia (PIN) GTX-006 (Acapodene) - Prostatic Intraepithelial Neoplasia | Phase 2 | Completed | GTx | 500 | 2001-04-01 | 2013-11-15 |
| Toremifene Followed by Radical Prostatectomy in Treating Patients With Stage I or Stage II Prostate Cancer toremifene, conventional surgery, neoadjuvant therapy - Prostate Cancer | Phase 2 | Completed | Joel Nelson, MD | 45 | 2001-04-01 | 2015-12-02 |
| Toremifene in Treating Patients With Ovarian Cancer toremifene - Ovarian Cancer | Phase 2 | Withdrawn | George Washington University | 1999-07-22 | 2017-07-13 | |
| Toremifene in Treating Patients With Desmoid Tumors toremifene, conventional surgery - Desmoid Tumor | Phase 2 | Completed | Advocate Lutheran General Hospital | 72 | 1991-07-01 | 2013-07-10 |
Breast Neoplasms (3) · Desmoid Tumors (2) · COVID-19 (1) · Carcinoma, Ovarian Epithelial (1) · Coronavirus Infections (1) · Ovarian Neoplasms (1) · Prostatic Intraepithelial Neoplasia (1) · Prostatic Neoplasms (1)
Advocate Lutheran General Hospital (1) · Fengxi Su (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · GTx (1) · George Washington University (1) · Japan Breast Cancer Research Network (1) · Joel Nelson, MD (1) · N.N. Petrov National Medical Research Center of Oncology (1) · Reena Mehra, MD (1) · UNC Lineberger Comprehensive Cancer Center (1)
United States (5) · China (1) · Italy (1) · Japan (1) · Russia (1)
Brian L. Samuels, MD (1) · Chiara Colombo, MD (1) · Dana Casey, MD (1) · James D. Ahlgren, MD (1) · Joel B. Nelson, MD (1) · Reena Mehra, MD (1) · Satoru Iwase, MD (1) · Tatiana Y Semiglazova, MD, PhD, DSc (1) · Vladimir F Semiglazov, MD,PhD, DSc, Professor (1)