25 completed, 17 unknown, 4 terminated, 2 recruiting. 50 Phase 2, 5 Phase 1, 3 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DURATION-GC: FLOT Plus Durvalumab and TS-1 Plus Durvalumab for Resectable Gastric Cancer Durvalumab, TS-1 - Resectable Gasrtic Cancer | Phase 2 | Not yet recruiting | Taipei Veterans General Hospital, Taiwan | 35 | 2026-09-01 | 2026-08-11 |
| Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma hypofractionated radiotherapy, PD-1 inhibitor, TS-1 - Gastroesophageal Junction Adenocarcinoma, Hypofractionated Radiotherapy | Phase 1 / Phase 2 | Recruiting | West China Hospital | 84 | 2025-11-18 | 2026-01-06 |
| Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer D07001-softgel capsules + Xeloda (or TS-1), mFOLFOX - Biliary Tract Cancer | Phase 2 / Phase 3 | Recruiting | InnoPharmax Inc. | 180 | 2022-03-29 | 2025-04-30 |
| Perioperative Leucovorin, Oxaliplatin, Docetaxel and S-1 (LOTS) For Locally Advanced Gastric or Gastroesophageal Junction Cancer leucovorin, oxaliplatin, docetaxel, S-1 - Gastric Cancer, Gastric Adenocarcinoma | Phase 2 | Unknown | National Cheng-Kung University Hospital | 58 | 2021-12-10 | 2023-11-15 |
| NGS as the First-line Treatment in Advanced Biliary Tract Cancer TS-1, Gemcitabine, Nivolumab - Advanced Biliary Tract Cancer | Phase 2 | Completed | National Health Research Institutes, Taiwan | 48 | 2019-12-27 | 2025-07-22 |
| Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With TS-1+Cisplatin or TS-1+Oxaliplatin as First Line Chemotherapy in Gastric Cancer (MK-3475-659/KEYNOTE-659) Pembrolizumab, Oxaliplatin, TS-1 - Gastric Cancer | Phase 2 | Completed | Merck Sharp & Dohme LLC | 100 | 2018-03-26 | 2024-06-11 |
| S-1, Irinotecan, and Oxaliplatin in Locally-Advanced Pancreatic Cancer Tegafur-gimeracil-oteracil potassium, Oxaliplatin, Irinotecan - Pancreatic Ductal Adenocarcinoma | Phase 2 | Unknown | National Taiwan University Hospital | 35 | 2017-11-01 | 2017-10-20 |
| Docetaxel and S-1 Combination Therapy as Second-line Treatment for Advanced Gastric Cancer Docetaxel, S-1 - Advanced Gastric Cancer | Phase 2 | Unknown | Fujian Cancer Hospital | 47 | 2017-06-01 | 2017-05-08 |
| Preoperative Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma TS-1 + cisplatin, radiation - Gastric Adenocarcinoma | Phase 2 | Completed | Yonsei University | 102 | 2016-12-12 | 2024-12-27 |
| Adjuvant Gemcitabine Versus Gemcitabine With Chemoradiation in Pancreatic Adenocarcinoma With R1 Resection and/or Positive Lymph Nodes Gemcitabine, TS-1 with radiation - Pancreatic Neoplasms | Phase 2 | Unknown | Peking Union Medical College Hospital | 110 | 2016-03-01 | 2016-04-28 |
| S-1/Oxaliplatin for High Risk Patients Who Underwent Gastrectomy S-1 (452500ACH), OXALIPLATIN (205803BIJ) - Stomach Cancer | Phase 2 | Terminated | Kangbuk Samsung Hospital | 8 | 2015-05-01 | 2022-12-08 |
| Study of Oxaliplatin, Irinotecan, and S-1 in Gastric Cancer Oxaliplatin, Irinotecan, S-1(OIS) - Stomach Neoplasm | Phase 2 | Completed | Hallym University Medical Center | 44 | 2015-02-01 | 2017-08-23 |
| A Randomized Phase II Trial of Neoadjuvant Chemotherapy Compared With Chemoradiotherapy in Gastric Adenocarcinoma SIB-IMRT, S-1, Surgery - Stomach Neoplasms, Neoadjuvant Therapy | Phase 2 | Completed | Chinese Academy of Medical Sciences | 71 | 2014-01-01 | 2019-10-16 |
| First Line Chemotherapy for Advanced Cancer albumin-bounded paclitaxel, S-1 - Gastric Cancer | Phase 2 | Terminated | Chinese Academy of Medical Sciences | 36 | 2013-09-01 | 2016-06-14 |
| SOX Versus XELOX for Patients With Peritoneal Metastasis of Colorectal Cancer SOX, XELOX - Colorectal Neoplasm | Phase 2 | Unknown | The First People's Hospital of Changzhou | 60 | 2013-01-01 | 2016-08-19 |
| Phase II Study of Gemcitabine Versus S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract Cancer Gemcitabine, S-1 - Biliary Tract Cancer | Phase 2 | Completed | Kansai Hepatobiliary Oncology Group | 70 | 2013-01-01 | 2018-05-16 |
| Cisplatin,Docetaxel and S-1 for Advanced Gastric and Gastroesophageal Junction Cancer Docetaxel, Cisplatin, S-1 - Gastric Cancer, Gastroesophageal Junction Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 40 | 2012-09-01 | 2012-12-12 |
| Study of DPD for Predicting Efficacy and Safety to S-1 Plus Oxaliplatin in Gastrointestinal Cancer S-1 plus oxaliplatin - Gastrointestinal Cancer | Phase 2 | Unknown | Xijing Hospital | 200 | 2012-03-01 | 2012-05-31 |
| Study of TS-1 as 2nd Line Treatment in Patients With Advanced Metastatic Breast Cancer Tegafur Gimeracil Oteracil Potassium Capsule - Breast Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 30 | 2011-12-01 | 2013-03-15 |
| Docetaxel and S-1 for Advanced Esophageal Cancer DS (docetaxel+S-1) - Esophageal Neoplasms | Phase 2 | Unknown | Hallym University Medical Center | 37 | 2011-11-01 | 2017-08-23 |
Showing 20 of 50. Sign in to see all of them.
Stomach Neoplasms (20) · Pancreatic Neoplasms (6) · Colorectal Neoplasms (5) · Biliary Tract Neoplasms (4) · Neoplasm Metastasis (4) · Breast Neoplasms (3) · Recurrence (2) · Bile Duct Neoplasms (1) · Carcinoma (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Esophageal Neoplasms (1) · Gastrointestinal Neoplasms (1) · Head and Neck Neoplasms (1) · Liver Diseases (1)
Chinese Academy of Medical Sciences (6) · Hallym University Medical Center (6) · Yonsei University (4) · Chonnam National University Hospital (2) · Hokkaido Gastrointestinal Cancer Study Group (2) · Japan Clinical Cancer Research Organization (2) · National Cancer Center, Korea (2) · Andrew Ko (1) · Fujian Cancer Hospital (1) · Gyeongsang National University Hospital (1) · InnoPharmax Inc. (1) · Japan Breast Cancer Research Network (1) · Kangbuk Samsung Hospital (1) · Kansai Hepatobiliary Oncology Group (1) · Korea University Anam Hospital (1)
South Korea (20) · China (13) · Japan (9) · Taiwan (4) · Singapore (1) · United States (1)
Dae Young Zang, MD, PhD (5) · Lin Yang, MD (2) · Sang-Hee Cho, M.D.Ph.D. (2) · Aiping Zhou, M.D (1) · Andrew Ko, MD (1) · Atsushi Sofuni, M.D. PhD (1) · Binghe Xu, MD, PhD (1) · Changping Wu, M.D. (1) · Chen Ming-Huang, MD (1) · Chia Jui Yen, M.D., Ph.D. (1) · Chiang Nai-Jung, MD (1) · Dae Young Zang, DM, PhD (1) · Daigo Yamamoto, MD (1) · Dong Hoe Koo, MD,PhD (1) · Heung Tae Kim, M.D. (1)
PMID 15160338, PMID 15169795, PMID 15289858, PMID 16822992, PMID 20708966, PMID 21444866, PMID 23497365, PMID 25106731, PMID 26109630, PMID 29372461, PMID 29743043, PMID 30982686, PMID 31765987, PMID 32145474, PMID 35574368, PMID 40885799