2 completed, 2 not yet recruiting. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Not yet recruiting 2 |
Follow thiamine hydrochloride: new trials by email Literature Review of thiamine hydrochloride trials Research Report on thiamine hydrochloride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| THiamine for Recovery In Vulnerable Early-life Infections thiamine hydrochloride 100 mg, Placebo - Meningitis, Bacteremia | Phase 2 | Not yet recruiting | Milton S. Hershey Medical Center | 240 | 2026-12-01 | 2026-10-09 |
| Oral Thiamine (Vitamin B1) for Depression in Children and Adolescents thiamine hydrochloride 100 mg - Major Depressive Disorder (MDD), Thiamine | Phase 2 | Not yet recruiting | Massachusetts General Hospital | 40 | 2026-10-01 | 2026-08-28 |
| Thiamine as a Renal Protective Agent in Septic Shock Thiamine Hydrochloride, Placebo - Sepsis, Kidney Injury | Phase 2 | Completed | Beth Israel Deaconess Medical Center | 95 | 2018-09-04 | 2023-06-27 |
| High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation Thiamine, Normal saline - Hematopoietic Stem Cell Transplantation, Delirium | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 66 | 2017-10-16 | 2021-10-19 |
Thiamine Deficiency (2) · Bacteremia (1) · Delirium (1) · Depressive Disorder, Major (1) · Meningitis (1) · Sepsis (1)
Beth Israel Deaconess Medical Center (1) · Massachusetts General Hospital (1) · Milton S. Hershey Medical Center (1) · UNC Lineberger Comprehensive Cancer Center (1)
United States (3)
Ari Moskowitz, MD (1) · Donald Rosenstein, MD (1) · Zev Nakamura, MD (1)
PMID 33945982, PMID 37364280, PMID 38321529
R01HD122957 (1)