7 completed, 4 unknown, 2 recruiting, 1 not yet recruiting. 5 Not applicable, 4 Phase 2, 3 Phase 3, 2 Phase 1, 1 Early Phase 1.
Follow Therapeutic Plasma Exchange: new trials by email Literature Review of Therapeutic Plasma Exchange trials Research Report on Therapeutic Plasma Exchange
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis Therapeutic Plasma Exchange, Rituximab, Intravenous immunoglobulin - Idiopathic Pulmonary Fibrosis | Phase 2 | Not yet recruiting | University of Alabama at Birmingham | 52 | 2026-12-01 | 2026-10-20 |
| Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers Best Practice, Biospecimen Collection, Central Venous Cannula Insertion - Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis and Ureter Urothelial Carcinoma | Phase 2 | Recruiting | Mayo Clinic | 70 | 2025-08-01 | 2026-05-08 |
| Therapeutic Plasma Exchange in Septic Shock: A Pilot Study Therapeutic Plasma Exchange - Septic Shock | Phase 2 | Recruiting | University of Manitoba | 80 | 2023-06-01 | 2025-08-17 |
| The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics Sham, Therapeutic Plasma Exchange, IVIG - Aging | Phase 3 | Unknown | Dobri Kiprov | 40 | 2022-09-12 | 2024-08-02 |
| Plasma Exchange in Covid-19 Patients With Anti-interferon Autoantibodies Therapeutic plasma exchange - COVID-19 | Phase 3 | Unknown | Centre Hospitalier St Anne | 50 | 2021-12-22 | 2022-01-10 |
| Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies Bortezomib, Busulfan, Cyclophosphamide - Beta Thalassemia Major, Sickle Beta 0 Thalassemia | Early Phase 1 | Withdrawn | M.D. Anderson Cancer Center | 2020-12-29 | 2024-10-24 | |
| Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis Therapeutic plasma exchange - Septic Shock | Phase 1 | Completed | Alberta Health Services, Calgary | 17 | 2020-10-21 | 2025-10-03 |
| Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients Therapeutic plasma exchange - COVID-19 | Phase 1 | Unknown | Larkin Community Hospital | 10 | 2020-09-11 | 2020-10-19 |
| Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 Patients Therapeutic plasma exchange - COVID-19 Pneumonia, COVID-19 Respiratory Infection | Not applicable | Completed | Novacescu Alexandru | 38 | 2020-07-25 | 2024-08-26 |
| Therapeutic Plasma Exchange Alone or in Combination With Ruxolitinib in COVID-19 Associated CRS Therapeutic Plasma Exchange, Ruxolitinib - Cytokine Release Syndrome, COVID19 | Phase 2 | Completed | Prisma Health-Upstate | 20 | 2020-04-30 | 2021-12-02 |
| Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan Therapeutic Plasma exchange, Convalescent Plasma, Tocilizumab - Covid19, Cytokine Release Syndrome | Not applicable | Completed | UNICEF | 600 | 2020-04-01 | 2020-07-30 |
| Therapeutic Plasma Exchange for Coronavirus Disease-2019 Triggered Cytokine Release Storm; Therapeutic Plasma Exchange - COVID-19, Cytokine Release Syndrome | Not applicable | Completed | UNICEF | 280 | 2020-04-01 | 2020-09-28 |
| RescuE pLAsma eXchange in Severe COVID-19 Therapeutic plasma exchange - Therapeutic Plasma Exchange, Covid19 | Not applicable | Terminated | Heidelberg University | 67 | 2020-01-07 | 2025-04-15 |
| Therapeutic Plasma Exchange in the Treatment of Sepsis Associated Multi-Organ Failure [SAMOF-TPE] Therapeutic plasma exchange - Sepsis | Not applicable | Unknown | Forsyth Medical Center | 300 | 2019-06-01 | 2019-02-18 |
| Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device Therapeutic plasma exchange - Autoimmune Diseases, Renal Disorders | Phase 3 | Completed | Fenwal, Inc. | 37 | 2010-09-01 | 2013-09-23 |
| Therapeutic Plasma Exchange in Thyrotoxicosis Therapeutic plasma exchange - Thyrotoxicosis | Completed | Baskent University | 27 | 1999-01-01 | 2020-07-24 |
COVID-19 (6) · Cytokine Release Syndrome (4) · Sepsis (3) · Respiratory Distress Syndrome (2) · Shock, Septic (2) · Anemia, Sickle Cell (1) · Autoimmune Diseases (1) · Coronavirus Infections (1) · Critical Illness (1) · Disease Progression (1) · Hematologic Diseases (1) · Idiopathic Pulmonary Fibrosis (1) · Kidney Diseases (1) · Nervous System Diseases (1) · Paraproteinemias (1)
UNICEF (2) · Alberta Health Services, Calgary (1) · Baskent University (1) · Centre Hospitalier St Anne (1) · Dobri Kiprov (1) · Fenwal, Inc. (1) · Forsyth Medical Center (1) · Heidelberg University (1) · Larkin Community Hospital (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Novacescu Alexandru (1) · Prisma Health-Upstate (1) · University of Alabama at Birmingham (1) · University of Manitoba (1)
United States (6) · Canada (2) · Pakistan (2) · France (1) · Germany (1) · Romania (1)
Dobri Kiprov, MD (1) · Emily Rimmer, MD, MSc (1) · George F Alvarez, MD (1) · Jacob J. Orme, MD, PhD (1) · Kris M Mahadeo (1) · Michael Talalaev, D.O. (1) · Monica Licker, MD, PhD (1) · Peyton Metzel, PhD (1) · Ryan Zarychanski, MD, MSc (1) · Sharshar Tarek, MD, PhD (1) · Steven R Duncan, MD (1) · Sumaira Irum, MIT (1) · W. Larry Gluck, MD (1)
PMID 26083430, PMID 30373638, PMID 33190086, PMID 34934447, PMID 38509495, PMID 40424097