5 unknown, 4 completed, 2 recruiting, 1 active not recruiting. 5 Not applicable, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Active not recruiting 1, Not yet recruiting 1 |
| Phase 4 | 2 | Recruiting 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Therapeutic Drug Monitoring: new trials by email Literature Review of Therapeutic Drug Monitoring trials Research Report on Therapeutic Drug Monitoring
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Therapeutic Drug Monitoring of Mycophenolate Mofetil in Lupus Nephritis Therapeutic Drug Monitoring, Standard clinical care - Systemic Lupus Erythematosus, Lupus Nephritis | Not applicable | Not yet recruiting | Federal University of Maranhao | 100 | 2026-07-01 | 2026-03-25 |
| Ensuring Access to Optimal Therapy in CF: The ENACT Study Elexacaftor / Ivacaftor / Tezacaftor, therapeutic drug monitoring - Cystic Fibrosis (CF) | Phase 4 | Recruiting | Arkansas Children's Hospital Research Institute | 100 | 2025-06-10 | 2026-06-02 |
| Ponatinib in Chronic Myeloid Leukemia Patients in Chronic Phase Therapeutic drug monitoring, Molecular Response - Chronic Myeloid Leukemia, Chronic Phase | Recruiting | University of Pisa | 100 | 2023-08-02 | 2025-06-05 | |
| Safety and Pharmacokinetics of Antipsychotics in Children 2: Studying TDM in an RCT Therapeutic Drug Monitoring, Risperidone plasma level - Autism Spectrum Disorder | Phase 4 | Unknown | Erasmus Medical Center | 140 | 2021-12-01 | 2023-12-08 |
| Therapeutic Drug Monitoring of Cardiac Medications Therapeutic drug monitoring - Hypertension, Coronary Artery Disease | Terminated | University of Texas Southwestern Medical Center | 77 | 2018-08-01 | 2023-05-16 | |
| TDM of Gentamicin and Vancomycin, in Neonates, Using Dried Blood Spot Sampling. therapeutic drug monitoring - Blood Sample for Routine Care, Term or Premature Newborns (28 to 44 Amenorrhea Weeks) | Unknown | University Hospital, Caen | 100 | 2017-12-15 | 2018-08-29 | |
| An Interventional Multidisciplinary Approach to Individualize Blood Pressure Treatment Therapeutic drug monitoring, Home blood pressure monitoring - Uncontrolled Hypertension | Not applicable | Active not recruiting | Oslo University Hospital | 1000 | 2017-11-01 | 2025-03-25 |
| Individualized Antiretroviral Therapy Pharmacogenomic index, Therapeutic drug monitoring - Pharmacogenetics, HIV | Not applicable | Completed | Hospital Italiano de Buenos Aires | 190 | 2017-10-05 | 2025-09-09 |
| The Norwegian Drug Monitoring Study Therapeutic drug monitoring, Standard care - Rheumatoid Arthritis, Spondyloarthritis | Not applicable | Completed | Diakonhjemmet Hospital | 611 | 2017-03-01 | 2021-03-08 |
| Observational Study Comparing the Efficacy of Ganciclovir as a Function of Blood Exposure to the Drug During a Curative or Preemptive Treatment Therapeutic Drug Monitoring - Solid Organ Transplantation | Unknown | Rennes University Hospital | 138 | 2017-02-21 | 2023-04-12 | |
| Study of Methotrexate Given to Juvenile Idiopathic Arthritis Patients Based on Pharmacogenomics and Pharmacometrics therapeutic drug monitoring - Juvenile Idiopathic Arthritis | Unknown | Guangzhou Women and Children's Medical Center | 100 | 2016-11-01 | 2016-12-30 | |
| Clinical Usefulness of Therapeutic Drug Monitoring of Colistin in Patients Treated With Colistin. Therapeutic drug monitoring - Multidrug-resistant Gram-negative Bacteria Infection | Not applicable | Completed | Seoul National University Hospital | 15 | 2016-01-01 | 2018-04-18 |
| Study of Tacrolimus Used for Pediatric Patients With Nephrotic Syndrome Based on Pharmacogenomics and Metabonomics therapeutic drug monitoring - Nephrotic Syndrome | Unknown | Guangzhou Women and Children's Medical Center | 150 | 2015-08-01 | 2016-08-12 | |
| Anti-HIV Drug Regimens With or Without Protease Inhibitors and Drug Level Monitoring in HIV Infected Adolescents Efavirenz + 2 NRTIs, Lopinavir/Ritonavir + 2 NRTIs, Therapeutic Drug Monitoring - HIV Infections | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 240 | 2004-07-01 | 2013-10-07 |
Arthritis, Juvenile (1) · Arthritis, Psoriatic (1) · Arthritis, Rheumatoid (1) · Autism Spectrum Disorder (1) · Colitis, Ulcerative (1) · Coronary Artery Disease (1) · Crohn Disease (1) · Cystic Fibrosis (1) · HIV Infections (1) · Hypertension (1) · Leukemia, Myeloid, Chronic-Phase (1) · Lupus Erythematosus, Systemic (1) · Lupus Nephritis (1) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (1) · Nephrotic Syndrome (1)
Guangzhou Women and Children's Medical Center (2) · Arkansas Children's Hospital Research Institute (1) · Diakonhjemmet Hospital (1) · Erasmus Medical Center (1) · Federal University of Maranhao (1) · Hospital Italiano de Buenos Aires (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Oslo University Hospital (1) · Rennes University Hospital (1) · Seoul National University Hospital (1) · University Hospital, Caen (1) · University of Pisa (1) · University of Texas Southwestern Medical Center (1)
United States (3) · China (2) · France (2) · Norway (2) · Argentina (1) · Brazil (1) · Italy (1) · Netherlands (1) · South Korea (1)
Espen A Haavardsholm, MD, PhD (1) · Jennifer S Guimbellot, Medical Degree and License (1) · Margarita Silio, MD (1) · Min Huang, Doctor (1) · Russell Van Dyke, MD (1) · Sara Galimberti, PhD (1) · Sverre E Kjeldsen, MD PhD (1) · Tore K Kvien, MD, PhD (1) · Waldo H Belloso, MD (1) · Wanpen Vongpatanasin (1) · Xiaolan Mo, master (1)
PMID 31902946, PMID 31907007, PMID 33944876, PMID 34275336, PMID 34932077, PMID 36539734, PMID 38530572, PMID 38543276, PMID 38606688, PMID 38713475, PMID 40616336, PMID 41856561
R01HL171034 (1)