20 completed, 8 terminated, 5 unknown, 1 recruiting. 20 Phase 1, 19 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 20 | Completed 12, Terminated 4, Unknown 3, Recruiting 1 |
| Phase 2 | 19 | Completed 9, Terminated 5, Unknown 3, Recruiting 1, Withdrawn 1 |
| Not applicable | 1 | Completed 1 |
Follow Therapeutic Autologous Dendritic Cells: new trials by email Literature Review of Therapeutic Autologous Dendritic Cells trials Research Report on Therapeutic Autologous Dendritic Cells
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC) Biopsy, Pembrolizumab, Therapeutic Autologous Dendritic Cells - Metastatic Microsatellite Stable Colorectal Carcinoma, Recurrent Colorectal Carcinoma | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2024-10-01 | 2024-09-26 | |
| Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer Atezolizumab, Bevacizumab, External Beam Radiation Therapy - Stage III Hepatocellular Carcinoma AJCC v8, Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 85 | 2019-09-19 | 2026-10-05 |
| Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma Cryosurgery, Pembrolizumab, Pheresis - Stage III Cutaneous Melanoma AJCC v7, Stage IIIA Cutaneous Melanoma AJCC v7 | Phase 1 / Phase 2 | Terminated | Mayo Clinic | 7 | 2017-11-15 | 2025-06-12 |
| Autologous Dendritic Cells in Treating Patients With Metastatic Kidney Cancer AdGMCAIX-transduced autologous dendritic cells, therapeutic autologous dendritic cells, laboratory biomarker analysis - Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer | Phase 1 | Completed | Jonsson Comprehensive Cancer Center | 12 | 2013-01-14 | 2021-08-04 |
| Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer allogeneic tumor cell vaccine, therapeutic autologous dendritic cells - Prostate Cancer | Phase 2 | Terminated | Mayo Clinic | 2 | 2009-01-01 | 2013-11-05 |
| Vaccine Therapy in Treating Patients With Acute Myeloid Leukemia in Complete Remission therapeutic autologous dendritic cells - Leukemia | Phase 1 | Completed | Institut Paoli-Calmettes | 10 | 2008-06-01 | 2011-05-13 |
| Vaccine Therapy and GM-CSF in Treating Patients With Recurrent or Metastatic Melanoma autologous tumor cell vaccine, sargramostim, therapeutic autologous dendritic cells - Melanoma (Skin) | Phase 2 | Completed | Hoag Memorial Hospital Presbyterian | 200 | 2006-12-01 | 2014-01-10 |
| Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women) therapeutic autologous dendritic cells, aromatase inhibition therapy, cyclophosphamide - Breast Cancer | Phase 2 | Completed | University of Nebraska | 17 | 2006-05-01 | 2023-09-29 |
| Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme tetanus toxoid, therapeutic autologous dendritic cells, therapeutic autologous lymphocytes - Malignant Neoplasms of Brain | Phase 1 | Completed | Gary Archer Ph.D. | 42 | 2006-02-06 | 2023-03-13 |
| Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast Cancer sargramostim, therapeutic autologous dendritic cells, trastuzumab - Breast Cancer | Phase 2 | Completed | UNC Lineberger Comprehensive Cancer Center | 17 | 2005-12-01 | 2018-09-12 |
| Denileukin Diftitox Followed by Vaccine Therapy in Treating Patients With Metastatic Cancer denileukin diftitox, recombinant fowlpox-CEA(6D)/TRICOM vaccine, therapeutic autologous dendritic cells - Breast Cancer, Colorectal Cancer | Phase 1 | Completed | H. Kim Lyerly | 24 | 2005-09-01 | 2012-11-12 |
| Vaccine Therapy in Treating Patients With Stage IV Melanoma autologous tumor cell vaccine, therapeutic autologous dendritic cells - Melanoma (Skin) | Phase 1 / Phase 2 | Unknown | Dermatologische Klinik MIT Poliklinik-Universitaetsklinikum Erlangen | 30 | 2005-04-01 | 2013-09-17 |
| Vaccine Therapy in Treating Patients With Liver or Lung Metastases From Colorectal Cancer falimarev, inalimarev, sargramostim - Colorectal Cancer, Metastatic Cancer | Phase 2 | Completed | Michael Morse, MD | 74 | 2005-02-01 | 2015-10-14 |
| Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Stage IB, Stage II, or Stage IIIA Non-Small Cell Lung Cancer autologous tumor cell vaccine, therapeutic autologous dendritic cells, adjuvant therapy - Lung Cancer | Phase 1 | Terminated | Jonsson Comprehensive Cancer Center | 15 | 2005-02-01 | 2008-01-28 |
| Vaccine Therapy in Treating Young Patients Who Are Undergoing Surgery for Malignant Glioma therapeutic autologous dendritic cells - Brain and Central Nervous System Tumors | Phase 1 | Completed | Jonsson Comprehensive Cancer Center | 7 | 2005-01-01 | 2020-08-05 |
| Vaccine Therapy in Treating Patients Who Are Undergoing Surgery for Ductal Carcinoma In Situ of the Breast therapeutic autologous dendritic cells, conventional surgery, neoadjuvant therapy - Breast Cancer | Phase 1 | Completed | Abramson Cancer Center at Penn Medicine | 30 | 2005-01-01 | 2014-09-17 |
| Vaccine Therapy With or Without Fludarabine in Treating Patients With Stage IV Kidney Cancer autologous tumor cell vaccine, keyhole limpet hemocyanin, therapeutic autologous dendritic cells - Kidney Cancer | Phase 2 | Unknown | St. Luke's Medical Center | 28 | 2004-08-01 | 2013-12-19 |
| Vaccine Therapy in Treating Patients With Acute Myeloid Leukemia autologous tumor cell vaccine, therapeutic autologous dendritic cells, tumor cell-derivative vaccine therapy - Leukemia | Phase 1 | Terminated | Boston Medical Center | 9 | 2004-04-01 | 2013-01-04 |
| Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma autologous dendritic cell-tumor fusion vaccine, gp100 antigen, therapeutic autologous dendritic cells - Melanoma (Skin) | Phase 2 | Unknown | Dana-Farber Cancer Institute | 40 | 2004-03-01 | 2009-02-09 |
| Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma autologous tumor cell vaccine, therapeutic autologous dendritic cells - Melanoma (Skin) | Phase 1 | Completed | Dartmouth-Hitchcock Medical Center | 2004-02-01 | 2015-02-02 |
Showing 20 of 35. Sign in to see all of them.
Melanoma (10) · Breast Neoplasms (6) · Prostatic Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Carcinoma, Renal Cell (3) · Colorectal Neoplasms (3) · Lung Neoplasms (3) · Astrocytoma (2) · Central Nervous System Neoplasms (2) · Colonic Neoplasms (2) · Congenital Abnormalities (2) · Glioblastoma (2) · Gliosarcoma (2) · Kidney Neoplasms (2) · Leukemia (2)
Jonsson Comprehensive Cancer Center (5) · Duke University (3) · Mayo Clinic (3) · National Cancer Institute (NCI) (3) · Roswell Park Cancer Institute (2) · UNC Lineberger Comprehensive Cancer Center (2) · University of Southern California (2) · Abramson Cancer Center at Penn Medicine (1) · Baylor Health Care System (1) · Boston Medical Center (1) · Dana-Farber Cancer Institute (1) · Dartmouth-Hitchcock Medical Center (1) · Dermatologische Klinik MIT Poliklinik-Universitaetsklinikum Erlangen (1) · Gary Archer Ph.D. (1) · H. Kim Lyerly (1)
United States (32) · Germany (2) · France (1)
Michael A. Morse, MD (3) · Gerold Schuler (2) · Jeffrey S. Weber, MD, PhD (2) · Johannes Vieweg, MD (2) · Jonathan S. Serody, MD (2) · Robert O. Dillman, MD, FACP (2) · Adam Lerner, MD (1) · Alexandra Drakaki, MD (1) · Arie Belldegrun, MD, FACS (1) · Brian J. Czerniecki, MD, PhD (1) · Christian Chabannon, MD, PhD (1) · Christopher P. Tretter, MD (1) · Crystal Mackall, M.D. (1) · David Avigan, MD (1) · Elizabeth C Reed, MD (1)
PMID 12727829, PMID 16061868, PMID 17822557, PMID 18519811, PMID 18676758, PMID 22996370, PMID 23377664, PMID 23657083, PMID 25762141, PMID 28411277, PMID 28422751, PMID 31406564, PMID 32316978, PMID 32925563, PMID 35135810
P50CA058223 (2), R21CA105837 (2), P30CA036727 (1), R01CA089102 (1), R01CA274985 (1), R01CA294704 (1)