4 completed, 1 terminated. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Terminated 1 |
Follow Gary Archer Ph.D.: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma CMV-DCs with GM-CSF, Td (tetanus toxoid) - Glioblastoma, Malignant Glioma | Phase 1 | Completed | Gary Archer Ph.D. | 11 | 2018-10-05 | 2021-01-28 |
| Intracerebral EGFR-vIII CAR-T Cells for Recurrent GBM EGFRvIII-CARs - Recurrent Glioblastoma, Recurrent Gliosarcoma | Phase 1 | Terminated | Gary Archer Ph.D. | 2 | 2018-05-30 | 2021-04-05 |
| Nivolumab With DC Vaccines for Recurrent Brain Tumors nivolumab, DC - Malignant Glioma, Astrocytoma | Phase 1 | Completed | Gary Archer Ph.D. | 6 | 2016-01-01 | 2020-03-26 |
| Basiliximab in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Undergoing Targeted Immunotherapy and Temozolomide-Caused Lymphopenia RNA-loaded dendritic cell vaccine, basiliximab - Malignant Neoplasms Brain | Phase 1 | Completed | Gary Archer Ph.D. | 34 | 2007-04-24 | 2021-03-09 |
| Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme tetanus toxoid, therapeutic autologous dendritic cells, therapeutic autologous lymphocytes - Malignant Neoplasms of Brain | Phase 1 | Completed | Gary Archer Ph.D. | 42 | 2006-02-06 | 2023-03-13 |
Glioblastoma (5) · Glioma (3) · Gliosarcoma (3) · Astrocytoma (2) · Brain Neoplasms (1) · Medulloblastoma (1) · Recurrence (1)
Tetanus Toxoid (2) · Basiliximab (1) · Diphtheria Toxoid (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · Nivolumab (1) · lentiviral minigene vaccine of COVID-19 coronavirus (1)
United States (5)
Daniel Landi, MD (2) · Katherine Peters, MD, PhD (2) · David Ashley, MBBS, FRACP, PhD (1) · Mustafa Khasraw, MD (1)
PMID 21768296, PMID 25762141, PMID 28411277
P30CA014236 (1), P50CA108786 (1), P50CA190991 (1)