19 completed, 5 unknown, 2 recruiting. 8 Phase 3, 5 Not applicable, 4 Phase 4, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 7, Recruiting 1 |
| Not applicable | 5 | Completed 3, Unknown 2 |
| Phase 4 | 4 | Unknown 3, Completed 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow TachoSil: new trials by email Literature Review of TachoSil trials Research Report on TachoSil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effectiveness and Safety of TachoSil® Fibrin Sealant Patch for Supporting Dural Sealing Among Adult Inpatients TachoSil®, DuraSeal® - Cerebrospinal Fluid (CSF) Leak, Psuedomeningocele | Recruiting | Corza Medical GmbH | 600 | 2026-02-13 | 2026-11-10 | |
| A Study to Compare the Efficacy and Safety of TachoSil and Surgicel Original as an Adjunct to Control Mild to Moderate Soft Tissue Bleeding During Surgery TachoSil, Surgicel Original - Hemorrhage | Phase 3 | Recruiting | Corza Medical GmbH | 116 | 2025-04-02 | 2026-06-30 |
| Trans Canal Tympanoplasty With Local Anesthesia Using Fat Graft and "TachoSil" Tympanoplasty performed under local anesthesia using fat graft and "Tachosil". - Tympanic Membrane Perforation | Not applicable | Unknown | HaEmek Medical Center, Israel | 20 | 2024-09-01 | 2024-08-13 |
| Use of Fibrin Sealant Patch for Vein Anastomosis During Deceased Donor Liver Transplantation- Randomized Clinical Trial TachoSil - Liver Transplant; Complications | Phase 4 | Unknown | Medical University of Warsaw | 170 | 2023-11-04 | 2024-02-28 |
| GATT-Patch Versus TachoSil in Liver Surgery GATT-Patch (currently named ETHIZIA), TachoSil - Intraoperative Bleeding, Hemorrhage, Surgical | Not applicable | Completed | GATT Technologies BV | 132 | 2022-08-04 | 2026-03-04 |
| Observational Pilot Study With TachoSil as a Ventricular Sealant TachoSil - Intraventricular Neoplasm | Completed | Germans Trias i Pujol Hospital | 20 | 2022-05-01 | 2023-02-08 | |
| A Study Evaluating the Safety and Preliminary Efficacy of sFilm-FS in Controlling Parenchymal Bleeding During Elective Hepatic Surgery sFilm-FS, TACHOSIL® - Hemostasis, General Surgery | Phase 1 / Phase 2 | Completed | Sealantium Medical Ltd. | 33 | 2021-05-12 | 2025-03-21 |
| Repair of Tympanic Membrane Perforation Using Tachosil Under Local Anesthesia Tachosil, fascia and cartilage - Tympanic Membrane Perforation | Not applicable | Unknown | HaEmek Medical Center, Israel | 27 | 2020-06-30 | 2020-06-16 |
| Neoveil® Versus TachoSil® for the Treatment of Pulmonary Air Leaks Following Lung Operation TachoSil®, Neoveil® - Prolonged Air Leak, Postoperative Air Leak | Not applicable | Completed | University Hospital, Basel, Switzerland | 46 | 2020-04-01 | 2023-05-15 |
| Hemopatch Compared to TachoSil in Postoperative Air Leak Duration After Pulmonary Resection Hemopatch, Tachosil - Air Leak From Lung | Not applicable | Completed | Baxter Healthcare Corporation | 279 | 2018-06-26 | 2020-04-06 |
| The Effect of Application of TachoSil® in Pancreatoduodenectomy Fibrinogen/thrombin-coated collagen patch - Pancreatic Neoplasm, Pancreatic Periampullary Cancer | Phase 4 | Unknown | Asan Medical Center | 126 | 2017-02-27 | 2017-09-01 |
| RollOut -Pre-Rolled TachoSil in Laparoscopic Utilisation. A Non-Interventional Study Tachosil - Laparoscopy | Completed | Takeda | 131 | 2016-04-05 | 2020-03-19 | |
| The Efficacy of Tachosil® for Prevention of Hemorrhage After Loop Electrosurgical Excisional Procedure (LEEP) Tachosil - Cervical Intraepithelial Neoplasia, Cervical Cancer | Phase 4 | Unknown | Asan Medical Center | 268 | 2015-01-01 | 2017-05-31 |
| A Safety and Efficacy Study Comparing Fibrocaps and Tachosil in Hepatic Surgery Fibrocaps, TachoSil - Surgical Bleeding | Phase 3 | Completed | Mallinckrodt | 150 | 2014-11-01 | 2017-08-16 |
| Use of Tachosil® for Lymph Sealing During Surgery TachoSil® - Lymph Node Resection | Completed | Takeda | 233 | 2012-09-01 | 2016-12-19 | |
| Comparison of Efficacy and Safety of TachoSil® Versus Surgicel® Original for the Secondary Hemostatic Treatment of Needle Hole Bleeding in Vascular Surgery TachoSil®, Surgicel® Original - Bleeding | Phase 3 | Completed | Takeda | 150 | 2012-03-01 | 2017-02-08 |
| TASALL - TachoSil® Against Liquor Leak TachoSil®, Current Practice - Cerebrospinal Fluid Leaks | Phase 3 | Completed | Takeda | 726 | 2011-04-01 | 2014-07-25 |
| TachoSil® Versus Surgicel® Original for the Secondary Treatment of Local Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery TachoSil®, Surgicel® Original - Hemorrhage | Phase 3 | Completed | Takeda | 253 | 2010-08-01 | 2015-11-25 |
| Efficacy and Safety of Sangustop® as Haemostatic Agent Versus a Carrier-Bound Fibrin Sealant During Liver Resection Sangustop, Tachosil - Hemostasis, Liver Surgery | Phase 4 | Completed | Aesculap AG | 128 | 2010-01-01 | 2015-05-28 |
| Evaluation of TachoSil® Application on a Colorectal Anastomosis (TC-029-IM) TachoSil® - Colorectal Anastomosis | Phase 2 | Completed | Nycomed | 25 | 2008-06-01 | 2012-05-08 |
Showing 20 of 26. Sign in to see all of them.
Hemorrhage (4) · Blood Loss, Surgical (3) · Cerebrospinal Fluid Leak (2) · Liver Diseases (2) · Tympanic Membrane Perforation (2) · Cerebral Ventricle Neoplasms (1) · Intraoperative Complications (1) · Lung Diseases (1) · Meningitis (1) · Pancreatic Neoplasms (1) · Thrombosis (1) · Uterine Cervical Dysplasia (1) · Uterine Cervical Neoplasms (1)
Nycomed (6) · Takeda (6) · Asan Medical Center (2) · Corza Medical GmbH (2) · HaEmek Medical Center, Israel (2) · Aesculap AG (1) · Baxter Healthcare Corporation (1) · GATT Technologies BV (1) · Germans Trias i Pujol Hospital (1) · Mallinckrodt (1) · Medical University of Warsaw (1) · Sealantium Medical Ltd. (1) · University Hospital, Basel, Switzerland (1)
Denmark (6) · Germany (6) · United States (6) · Austria (5) · Netherlands (3) · Spain (3) · Italy (2) · Poland (2) · South Korea (2) · Belgium (1) · France (1) · Greece (1) · Russia (1) · Slovenia (1) · Sweden (1)
Didier Lardinois, Prof. MD (1) · Hans de Wilt (1) · Jaehoon Lee, Ph.D (1) · James Guarrera (1) · Martin Bodingbauer, MD (1) · Ning Rosenthal, MD, PhD, MPH, (1) · Orgad Laub, Professor (1) · Pilar Teixidor Rodriguez, MD, PhD (1)
PMID 16509475, PMID 19545437, PMID 24880345, PMID 25296539, PMID 26776356, PMID 27813467, PMID 28083041, PMID 28529027, PMID 28729143, PMID 28751035, PMID 29232819, PMID 31058968, PMID 31502003, PMID 33538867, PMID 34499261, PMID 34916315, PMID 36651370, PMID 37551841, PMID 39331127, PMID 39842025, PMID 42177141
2004 (2), 2014 (1), 2017 (1), 2019 (1)