10 completed, 5 recruiting, 1 unknown. 16 Phase 2, 8 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 10, Recruiting 5, Unknown 1 |
| Phase 1 | 8 | Completed 4, Recruiting 4 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
Follow Supportive care: new trials by email Literature Review of Supportive care trials Research Report on Supportive care
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLC Dual-target CAR-NK cells, Lymphodepleting chemotherapy, Supportive care - Non-Small Cell Lung Cancer, Advanced/Metastatic | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 60 | 2026-03-02 | 2026-06-11 |
| Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC Dual-target CAR-NK cells, Lymphodepleting chemotherapy, Supportive Care - Non-Small Cell Lung Cancer, Advanced/Metastatic NSCLC | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 48 | 2026-02-02 | 2026-03-12 |
| Dual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBC Dual-target CAR-NK cells, Lymphodepleting, Supportive care - Breast Cancer (Advanced/Metastatic), HER2-positive Breast Cancer | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 60 | 2026-02-02 | 2026-04-06 |
| Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC) Dual-target CAR-NK cells (EB-DT-CAR-NK), Lymphodepleting chemotherapy, Supportive care - Breast Cancer (Locally Advanced or Metastatic), HER2-positive Breast Cancer | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 60 | 2026-02-02 | 2026-03-20 |
| Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural Mesothelioma Gemcitabine, supportive care - Malignant Pleural Mesothelioma | Phase 2 | Completed | Ain Shams University | 40 | 2023-04-01 | 2024-08-27 |
| The Use of Eltrombopag Post HSCT in BMFD Eltrombopag 25 MG Oral Tablet, Supportive care - Stem Cell Transplant Complications | Phase 2 / Phase 3 | Completed | The First Affiliated Hospital of Soochow University | 118 | 2022-10-22 | 2025-12-03 |
| AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission Azacitidine, Venetoclax, Supportive care - Acute Myeloid Leukemia (AML) in Remission | Phase 2 / Phase 3 | Recruiting | The First Affiliated Hospital of Soochow University | 124 | 2022-06-25 | 2022-08-19 |
| Avatrombopag to Promote Platelet Engraftment After Allo-HSCT Avatrombopag, Supportive care - Platelet Disorder | Phase 2 | Unknown | The First Affiliated Hospital of Soochow University | 20 | 2021-12-01 | 2022-12-23 |
| Molecular Profiling and Matched Targeted Therapy for Patients With Unresectable Advanced or Metastatic Melanoma Standard therapy or clinical trial, Matched targeted therapy, Trametinib and / or supportive care - Melanoma | Phase 2 | Completed | Melanoma Institute Australia | 216 | 2021-11-22 | 2026-05-29 |
| Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease) Mesenchymal Stromal Cells, Supportive Care - Sars-CoV2, Acute Respiratory Distress Syndrome | Phase 1 / Phase 2 | Completed | Baylor College of Medicine | 28 | 2021-02-12 | 2026-10-21 |
| Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants Zanubrutinib, Supportive Care, Placebo - COVID-19 Pulmonary Complications, COVID-19 | Phase 2 | Completed | BeiGene | 63 | 2020-07-06 | 2024-10-26 |
| Efficacy of Convalescent Plasma Therapy in Severely Sick COVID-19 Patients Convalescent Plasma Transfusion, Supportive Care, Random Donor Plasma - COVID | Phase 2 | Completed | Institute of Liver and Biliary Sciences, India | 29 | 2020-04-20 | 2020-06-12 |
| Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer vitamin C, Modulated Electro-Hyperthermia (mEHT), Supportive care - Carcinoma, Non-Small-Cell Lung, Stage IIIA Non-small Cell Lung Cancer | Phase 1 / Phase 2 | Completed | Clifford Hospital, Guangzhou, China | 97 | 2015-12-01 | 2018-11-30 |
| Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) decitabine and cytarabine, Supportive Care - Acute Myeloid Leukemia | Phase 2 | Completed | Annie Im, M.D. | 44 | 2013-02-01 | 2019-11-14 |
| A Controlled Clinical Trial on The Use of a Specific Antivenom Against Envenoming by Bungarus Multicinctus Bungarus multicinctus-candidus Antivenom, Supportive Care - Snake Bite | Phase 1 / Phase 2 | Completed | Hanoi Medical University | 81 | 2004-03-01 | 2008-12-18 |
| Sirolimus in Treating Patients With Glioblastoma Multiforme Rapamycin, Surgery, Supportive Care - Brain and Central Nervous System Tumors | Phase 1 / Phase 2 | Completed | Jonsson Comprehensive Cancer Center | 13 | 2002-07-01 | 2020-08-03 |
Carcinoma, Non-Small-Cell Lung (3) · Neoplasm Metastasis (3) · Breast Neoplasms (2) · COVID-19 (2) · Leukemia, Myeloid, Acute (2) · Thrombocytopenia (2) · Triple Negative Breast Neoplasms (2) · Blood Platelet Disorders (1) · Bone Marrow Failure Disorders (1) · Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Glioblastoma (1) · Gliosarcoma (1) · Melanoma (1) · Mesothelioma (1)
Beijing Biotech (4) · The First Affiliated Hospital of Soochow University (3) · Ain Shams University (1) · Annie Im, M.D. (1) · Baylor College of Medicine (1) · BeiGene (1) · Clifford Hospital, Guangzhou, China (1) · Hanoi Medical University (1) · Institute of Liver and Biliary Sciences, India (1) · Jonsson Comprehensive Cancer Center (1) · Melanoma Institute Australia (1)
China (8) · United States (4) · Australia (1) · Egypt (1) · India (1) · Vietnam (1)
Abanoub Samir (1) · Alex Menzies (1) · Annie Im, MD (1) · Depei Wu, PhD,MD (1) · Helen Heslop, MD (1) · Junwen Ou, PhD (1) · LaQuisa Hill, MD (1) · Suning Chen (1) · Timothy F. Cloughesy, MD (1) · Yue Han (1)
PMID 11174237, PMID 11837876, PMID 18215105, PMID 20358414, PMID 34013969, PMID 34376578, PMID 36734509, PMID 37162745, PMID 38258329, PMID 39906744, PMID 40501447, PMID 8544231, PMID 9042094, PMID 9509180, PMID 9792162