47 completed, 25 recruiting, 9 unknown, 7 not yet recruiting. 73 Not applicable, 16 Phase 2, 9 Phase 1, 6 Phase 3, 2 Early Phase 1.
Follow Supportive Care: new trials by email Literature Review of Supportive Care trials Research Report on Supportive Care
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Physiatry-Led Cancer Prehabilitation During Neoadjuvant Systemic Therapy to Improve Function in Stage III-IVA Gynecologic Cancer Patients Educational Intervention, Goal Setting, Interview - Malignant Female Reproductive System Neoplasm | Not applicable | Not yet recruiting | City of Hope Medical Center | 25 | 2026-11-13 | 2026-05-27 |
| Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial Aerobic Exercise, Biospecimen Collection, Dietary Intervention - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 90 | 2026-10-10 | 2026-07-23 |
| Personalized Exercise Program for Survivors of Breast Cancer, STEPS-BC Trial Exercise Intervention, Educational Intervention, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | Wake Forest University Health Sciences | 120 | 2026-10-02 | 2026-10-06 |
| PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors Supportive Care - Brain Injuries, Acute, Brain Tumor Adult | Not applicable | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 160 | 2026-10-01 | 2026-05-19 |
| Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers Accelerometry, Aerobic Exercise, Biospecimen Collection - Lung Carcinoma | Not applicable | Not yet recruiting | Roswell Park Cancer Institute | 200 | 2026-09-15 | 2026-08-21 |
| A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer Best Practice, Interview, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | City of Hope Medical Center | 126 | 2026-09-09 | 2026-10-16 |
| Geriatric Assessment and Management for Older Adults Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer and Their Family Caregivers Best Practice, Electronic Health Record Review, Health Communication - Localized Head and Neck Carcinoma | Not applicable | Recruiting | City of Hope Medical Center | 36 | 2026-08-25 | 2026-10-20 |
| Peer Support Program for Improving Quality of Life Among Head and Neck Patients, Connecting Through Cancer Trial Supportive Care, Survey Administration, Interview - Malignant Head and Neck Neoplasm | Not applicable | Not yet recruiting | OHSU Knight Cancer Institute | 56 | 2026-07-16 | 2026-07-15 |
| WE-CARE Community Health Forums to Increase Breast Cancer Screening and Clinical Trial Participation for Rural and Low Income Women Educational Intervention, Patient Navigation, Supportive Care - Breast Carcinoma | Not applicable | Terminated | Mayo Clinic | 1 | 2026-06-30 | 2026-09-14 |
| Telephone-Based Coaching Sessions (TAC) to Improve Advance Care Planning Participation in Advanced Cancer Patients and Their Support Person Supportive Care, Telephone-Based Intervention, Survey Administration - Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm | Not applicable | Recruiting | Fred Hutchinson Cancer Center | 80 | 2026-04-08 | 2026-08-25 |
| Comparative Evaluation of Oral Ursodeoxycholic Acid in Reducing Bilirubin Levels Among Patients With Acute Viral Hepatitis Ursodeoxycholic Acid, Supportive Care - Hepatitis A, Hepatitis E Virus Infection | Not applicable | Not yet recruiting | Combined Military Hospital, Pakistan | 88 | 2026-04-01 | 2026-04-13 |
| Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway Supportive Care - Cancer, Frail | Not applicable | Recruiting | Wake Forest University Health Sciences | 32 | 2026-03-16 | 2026-07-02 |
| Dual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLC Dual-target CAR-NK cells, Lymphodepleting chemotherapy, Supportive care - Non-Small Cell Lung Cancer, Advanced/Metastatic | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 60 | 2026-03-02 | 2026-06-11 |
| Mobile-Based Telemedicine and Health-Related Quality of Life Among Patients With Chronic Heart Failure (MOBILE-HF) Supportive Care - Chronic Heart Failure, Health Related Quality of Life | Not applicable | Recruiting | Select College | 72 | 2026-03-02 | 2026-06-17 |
| Laughter Yoga and Sleep Hygiene Training for College Students With Premenstrual Syndrome Supportive Care - Laughter Yoga, Premenstrual Syndrome-PMS | Not applicable | Completed | Gazi University | 45 | 2026-03-01 | 2026-05-20 |
| Comparison of Outcomes of Management of Bowel Obstruction Dexamethasone, Supportive Care - Adhesive Small Bowel Obstruction | Phase 4 | Recruiting | University of Washington | 550 | 2026-02-03 | 2026-05-07 |
| Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC Dual-target CAR-NK cells, Lymphodepleting chemotherapy, Supportive Care - Non-Small Cell Lung Cancer, Advanced/Metastatic NSCLC | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 48 | 2026-02-02 | 2026-03-12 |
| Dual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBC Dual-target CAR-NK cells, Lymphodepleting, Supportive care - Breast Cancer (Advanced/Metastatic), HER2-positive Breast Cancer | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 60 | 2026-02-02 | 2026-04-06 |
| Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC) Dual-target CAR-NK cells (EB-DT-CAR-NK), Lymphodepleting chemotherapy, Supportive care - Breast Cancer (Locally Advanced or Metastatic), HER2-positive Breast Cancer | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 60 | 2026-02-02 | 2026-03-20 |
| Educational Program for the Multidisciplinary Support of Patients With Endometriosis Supportive Care - Endometriosis | Not applicable | Recruiting | Centre Hospitalier Emile Roux | 260 | 2025-12-17 | 2025-12-22 |
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Breast Neoplasms (11) · Neoplasms (6) · Glioblastoma (5) · Leukemia, Myeloid, Acute (5) · Ovarian Neoplasms (5) · Carcinoma, Non-Small-Cell Lung (4) · Lung Neoplasms (4) · Neoplasm Metastasis (4) · Triple Negative Breast Neoplasms (4) · COVID-19 (3) · Colorectal Neoplasms (3) · Endometrial Neoplasms (3) · Motor Activity (3) · Myelodysplastic Syndromes (3) · Prostatic Neoplasms (3)
City of Hope Medical Center (6) · Fred Hutchinson Cancer Center (6) · M.D. Anderson Cancer Center (5) · Beijing Biotech (4) · Mayo Clinic (4) · Wake Forest University Health Sciences (4) · Ohio State University Comprehensive Cancer Center (3) · Roswell Park Cancer Institute (3) · The First Affiliated Hospital of Soochow University (3) · Copenhagen University Hospital, Rigshospitalet (2) · Duke University (2) · Emory University (2) · Gazi University (2) · University of Pittsburgh (2) · University of Washington (2)
United States (54) · China (9) · France (6) · Turkey (Türkiye) (6) · Canada (3) · Denmark (3) · Australia (2) · Egypt (2) · Sweden (2) · Brazil (1) · Ethiopia (1) · India (1) · Israel (1) · Malaysia (1) · Pakistan (1)
Eileen Hacker, PHD (2) · Abanoub Samir (1) · Alain Combes, MD (1) · Alex Menzies (1) · Allison De Villiers, MSN, RN, ONC (1) · Alyx B Porter Umphrey (1) · Amr K Abo Takia, MD (1) · Andrew D Ray (1) · Anna Halpern (1) · Anne Reb (1) · Annie Im, MD (1) · Arya Amini (1) · Benzi M Kluger, MD, MS (1) · Boris Duchemann (1)
PMID 10337648, PMID 10459885, PMID 10646723, PMID 11174237, PMID 11308246, PMID 11837876, PMID 11841126, PMID 11914437, PMID 1472184, PMID 15162149, PMID 16025260, PMID 1609875, PMID 16163448, PMID 16253509, PMID 16284994, PMID 16300724, PMID 16331595, PMID 16719675, PMID 17020807, PMID 17084483, PMID 17129895, PMID 17239330, PMID 17323529, PMID 17394940, PMID 17462312, PMID 17563467, PMID 17710445, PMID 18000503, PMID 18005911, PMID 18089136, PMID 18215105, PMID 18243937, PMID 18502246, PMID 18558664, PMID 19142857, PMID 1997103, PMID 20067645, PMID 20099952, PMID 20358414, PMID 21149672, PMID 21231781, PMID 21376664, PMID 21767025, PMID 21833957, PMID 22289425, PMID 22628419, PMID 22644537, PMID 22984800, PMID 22988317, PMID 23152241
P30CA033572 (4), P30CA012197 (3), P30CA015704 (2), P30CA138292 (2), K01HL133466 (1), P30CA015083 (1), P30CA016672 (1), P30CA051008 (1), P50CA159981 (1), R01CA268004 (1), R01CA291768 (1), R01HG002686 (1), R01NR013428 (1), R01NR016037 (1), R21CA258105 (1)