2 completed, 2 not yet recruiting, 2 recruiting, 1 active not recruiting. 3 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Active not recruiting 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Recruiting 1 |
Follow Sham procedure control: new trials by email Literature Review of Sham procedure control trials Research Report on Sham procedure control
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Stellate Ganglion Neuromodulation for the Treatment of Electrical Storm Stellate Ganglion Block Injection with Bupivicaine, Sham procedure control - Ventricular Tachycardia (V-Tach) Storm | Not applicable | Not yet recruiting | Population Health Research Institute | 300 | 2027-01-01 | 2026-10-08 |
| A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease Pulmonary Artery Denervation (PADN), Sham procedure control - Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction | Not applicable | Recruiting | Pulnovo Medical, Inc. | 750 | 2026-08-21 | 2026-11-10 |
| A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD BS01, Sham procedure control - Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD) | Phase 1 / Phase 2 | Recruiting | Bionic Sight LLC | 40 | 2026-01-08 | 2026-01-23 |
| Mesenchymal Stromal Cell Therapy to Prevent Bronchopulmonary Dysplasia in Extreme Preterm Infants Human Allogenic Umbilical Cord Mesenchymal Stromal Cells, Sham procedure control - Bronchopulmonary Dysplasia (BPD), ELGAN (22-28SA) | Phase 2 | Not yet recruiting | Ottawa Hospital Research Institute | 168 | 2025-10-01 | 2025-07-10 |
| Renal Denervation in Chronic Kidney Disease - RDN-CKD Study Renal denervation, Sham procedure control - Uncontrolled Hypertension, Renal Denervation | Not applicable | Active not recruiting | Hippocration General Hospital | 20 | 2024-07-04 | 2026-08-04 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) LYR-210, Sham procedure control, Background therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 182 | 2022-05-13 | 2026-02-19 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults LYR-210, Sham procedure control, Background Therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 196 | 2022-01-27 | 2025-05-02 |
Disease (2) · Bronchopulmonary Dysplasia (1) · Cardiovascular Diseases (1) · Geographic Atrophy (1) · Heart Failure (1) · Hypertension (1) · Hypertension, Pulmonary (1) · Premature Birth (1) · Renal Insufficiency, Chronic (1) · Tachycardia, Ventricular (1) · Vascular Diseases (1)
Lyra Therapeutics (2) · Bionic Sight LLC (1) · Hippocration General Hospital (1) · Ottawa Hospital Research Institute (1) · Population Health Research Institute (1) · Pulnovo Medical, Inc. (1)
United States (4) · Canada (2) · Poland (2) · Austria (1) · Belgium (1) · Bulgaria (1) · China (1) · Czechia (1) · Germany (1) · Greece (1) · Hungary (1) · Spain (1)
Gregg W. Stone (1)