6 completed, 4 recruiting, 1 active not recruiting, 1 not yet recruiting. 6 Phase 4, 2 Phase 1, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 2, Recruiting 2, Active not recruiting 1, Terminated 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow SGLT-2 inhibitor: new trials by email Literature Review of SGLT-2 inhibitor trials Research Report on SGLT-2 inhibitor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy SGLT-2 inhibitor, SGLT2 inhibitor - Duchenne Muscular Dystrophy (DMD) | Phase 1 | Recruiting | Vanderbilt University Medical Center | 10 | 2026-07-01 | 2026-08-24 |
| Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology (DELAY-HF), Pilot Study Sacubitril / Valsartan, SGLT-2 inhibitor, SGLT2 Inhibition - Heart Failure Due to Coronary Artery Disease, Valvular Cardiomyopathy | Phase 4 | Recruiting | Kyungsub Song | 80 | 2026-05-20 | 2026-09-02 |
| SGLT2 Inhibitors and Survival in Lung Cancer Patients With Diabetes SGLT-2 inhibitor, Sham (No Treatment) - Lung Cancer | Not applicable | Not yet recruiting | Shanghai Chest Hospital | 200 | 2025-12-07 | 2025-12-09 |
| SGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients SGLT-2 inhibitor, Placebo - Kidney Transplantation Recipients, Sodium-Glucose Transporter 2 Inhibitors | Phase 4 | Recruiting | Odense University Hospital | 88 | 2025-09-01 | 2025-08-27 |
| The Use of Advanced Imaging in HFpEF Advanced imaging, SGLT-2 inhibitor - Heart Failure With Preserved Ejection Fraction (HFPEF) | Recruiting | Sheffield Teaching Hospitals NHS Foundation Trust | 40 | 2025-08-05 | 2026-03-18 | |
| Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome Tadalafil 5 mg, SGLT-2 inhibitor, Tadalafil plus SGLT2 inhibitors - Erectile Dysfunction, Left Ventricular Diastolic Dysfunction | Phase 4 | Completed | Kafrelsheikh University | 60 | 2025-05-05 | 2026-05-04 |
| Antidiabetic Medications and Risk of Cancer Metformin, sulphonylurea, DPP-4 inhibitor - Cancer | Completed | University of Pecs | 74799 | 2025-03-15 | 2026-06-05 | |
| Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor Agonists SGLT-2 inhibitor, GLP1-RA - Type 2 Diabetes (T2DM) | Phase 4 | Active not recruiting | MaryAnn Banerji | 60 | 2024-12-21 | 2026-01-08 |
| Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors SGLT-2 inhibitor - Diabetes, Type1diabetes | Phase 1 | Completed | McGill University | 24 | 2024-12-05 | 2026-09-25 |
| SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal Insufficiency SGLT-2 inhibitor - Heart Failure With Reduced Ejection Fraction, Renal Insufficiency, Chronic | Phase 4 | Terminated | Peking University People's Hospital | 11 | 2023-03-09 | 2024-04-30 |
| Hydroxyl Free Radical Associated Effects of SGLT-2 Inhibitors in Type 2 Diabetes SGLT-2 inhibitor - T2DM | Completed | University of Pecs | 40 | 2022-07-18 | 2025-01-28 | |
| Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea Dapagliflozin (Forxiga), Vitamin D3 ( Colecalciferol), Vitamin D3 plus Dapagliflozin - Obstructive Sleep Apnea | Phase 3 | Completed | University Malaysia Sarawak | 160 | 2022-06-08 | 2024-11-15 |
| SGLT2i and Incretin and CRTd. Incretin Effect, Cardiac Resynchronization therapy defibrillator device, SGLT-2 inhibitor - Type 2 Diabetes Mellitus, Heart Failure | Phase 4 | Completed | University of Campania Luigi Vanvitelli | 500 | 2017-09-01 | 2025-06-25 |
Diabetes Mellitus, Type 2 (3) · Heart Failure (3) · Cardiomyopathies (1) · Diabetes Mellitus (1) · Erectile Dysfunction (1) · Heart Valve Diseases (1) · Hypertension (1) · Lung Neoplasms (1) · Metabolic Syndrome (1) · Motor Activity (1) · Muscular Dystrophies (1) · Muscular Dystrophy, Duchenne (1) · Neoplasms (1) · Renal Insufficiency, Chronic (1) · Sleep Apnea, Obstructive (1)
University of Pecs (2) · Kafrelsheikh University (1) · Kyungsub Song (1) · MaryAnn Banerji (1) · McGill University (1) · Odense University Hospital (1) · Peking University People's Hospital (1) · Shanghai Chest Hospital (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1) · University Malaysia Sarawak (1) · University of Campania Luigi Vanvitelli (1) · Vanderbilt University Medical Center (1)
Hungary (2) · United States (2) · Canada (1) · China (1) · Denmark (1) · Egypt (1) · Italy (1) · Malaysia (1) · South Korea (1) · United Kingdom (1)
Kyungsub Song, MD (1) · Larry W. Markham, MD (1) · Lotte B Lange, MD (1) · Mary Ann Banerji, MD (1) · Michael Tsoukas, M.D. (1) · Mohamed G Abdelraouf, MD (1) · Reda B Bastawisy, MD (Professor) (1) · Wael A Haseeb, MD (Assistant professor) (1)
R61HL180327 (1)