4 completed, 4 terminated, 2 unknown, 1 active not recruiting. 8 Phase 2, 3 Phase 1, 2 Not applicable, 1 Early Phase 1.
Follow Selenomethionine: new trials by email Literature Review of Selenomethionine trials Research Report on Selenomethionine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab Selenomethionine (SLM), Axitinib, Pembrolizumab - Clear Cell Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma Metastatic | Phase 1 / Phase 2 | Active not recruiting | Mohammed Milhem | 55 | 2022-09-19 | 2025-12-10 |
| Optimal Selenium for Bowel Polyps (OSCAR) Selenomethionine, Methylselenocysteine - Colorectal Adenoma | Phase 1 | Completed | University of Auckland, New Zealand | 56 | 2022-05-06 | 2025-01-22 |
| SLM + Axitinib for Clear Cell RCC Selenomethionine (SLM), Axitinib - Advanced Metastatic Clear Cell Renal Cell Carcinoma (CCRCC) | Phase 1 / Phase 2 | Completed | Mohammed Milhem | 45 | 2016-01-01 | 2026-05-06 |
| Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT Selenomethionine, Placebo - Thyroiditis Autoimmune | Phase 2 | Unknown | University of Siena | 60 | 2012-12-01 | 2014-11-27 |
| Colon Cancer Prevention Using Selenium Selenium, selenomethionine, placebo - Prevention of Colorectal Cancer | Early Phase 1 | Unknown | University of Illinois at Chicago | 50 | 2010-12-01 | 2010-09-29 |
| Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy selenomethionine, placebo, cisplatin - Chemotherapeutic Agent Toxicity, Mucositis | Phase 2 | Terminated | Roswell Park Cancer Institute | 18 | 2009-06-01 | 2014-08-22 |
| Selenomethionine and Finasteride Before Surgery or Radiation Therapy in Treating Patients With Stage I or Stage II Prostate Cancer selenomethionine, finasteride, placebo - Prostate Cancer | Phase 2 | Completed | Roswell Park Cancer Institute | 55 | 2008-08-01 | 2023-10-02 |
| Selenomethionine in Treating Patients Undergoing Surgery or Internal Radiation Therapy for Stage I or Stage II Prostate Cancer selenomethionine, placebo - Prostate Cancer | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2008-08-01 | 2012-02-06 | |
| Influence of Selenium on Prostate Cancer Related Biomarkers Placebo, selenomethionine, low dose selenized-yeast - Effect of Selenium on Oxidative Stress in Healthy Men | Not applicable | Completed | Milton S. Hershey Medical Center | 130 | 2008-05-01 | 2015-07-10 |
| Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma selenomethionine, capecitabine, oxaliplatin - Colorectal Cancer | Phase 2 | Terminated | Roswell Park Cancer Institute | 5 | 2008-03-01 | 2017-11-17 |
| Carboplatin, Paclitaxel, Selenomethionine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery selenomethionine, carboplatin, paclitaxel - Lung Cancer | Phase 2 | Terminated | Roswell Park Cancer Institute | 16 | 2006-10-01 | 2017-11-28 |
| Selenium Supplementation of Patients With Cirrhosis 200 µg selenium as selenate, 400 µg selenium as selenate, 200 µg selenium as selenomethionine - Liver Disease | Not applicable | Terminated | Vanderbilt University | 99 | 2006-02-01 | 2012-03-07 |
Prostatic Neoplasms (3) · Adenocarcinoma of Lung (1) · Adenocarcinoma, Bronchiolo-Alveolar (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Clear-cell metastatic renal cell carcinoma (1) · Colorectal Neoplasms (1) · Fibrosis (1) · Hashimoto Disease (1) · Kidney Neoplasms (1) · Liver Diseases (1) · Lung Neoplasms (1) · Mucositis (1) · Radiation Injuries (1) · Rectal Neoplasms (1)
Roswell Park Cancer Institute (5) · Mohammed Milhem (2) · Milton S. Hershey Medical Center (1) · University of Auckland, New Zealand (1) · University of Illinois at Chicago (1) · University of Siena (1) · Vanderbilt University (1)
United States (9) · New Zealand (2)
James L. Mohler, MD (2) · Anurag Singh (1) · Furio Pacini, MD (1) · Jorge Gomez, MD (1) · Karam El-Bayoumy, PhD (1) · Marwan Fakih, MD (1) · Michael Jameson, PhD (1) · Mohammed Milhem, MBBS (1) · Mohammed Milhem, MD (1) · Raymond F Burk, M.D. (1) · Richard V Benya, MD (1)
P30CA016056 (1), R01DK058763 (1)