5 terminated. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Terminated 5 |
Follow Saline Solution, Hypertonic: new trials by email Literature Review of Saline Solution, Hypertonic trials Research Report on Saline Solution, Hypertonic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension Hypertonic Saline and Terlipressin, Normal saline and norepinephrine - Septic Shock, Sepsis-associated Hypotension | Phase 3 | Terminated | Hospital General de Ciudad Real | 21 | 2012-06-01 | 2014-03-10 |
| Hypertonic Saline vs. Mannitol for Elevated Intercranial Pressure Mannitol, Hypertonic Saline - Traumatic Brain Injury, Elevated Intracranial Pressure | Phase 3 | Terminated | University of Cincinnati | 5 | 2010-04-01 | 2013-03-05 |
| Mannitol vs HS to Treat ICHT After Severe TBI : Comparison on PtiO2 and Microdialysis Values Hypertonic saline, Mannitol - Traumatic Brain Injury | Phase 3 | Terminated | Direction Centrale du Service de Santé des Armées | 30 | 2008-07-01 | 2012-08-08 |
| Hypertonic Resuscitation Following Severe Traumatic Brain Injury (TBI) 7.5% Hypertonic Saline in 6% Dextran-70 (HSD), 7.5% Hypertonic Saline (HS), 0.9% Normal Saline (NS) - Brain Injuries, Traumatic | Phase 3 | Terminated | University of Washington | 1331 | 2006-05-01 | 2011-05-19 |
| Hypertonic Resuscitation Following Traumatic Injury 7.5% hypertonic saline/6% Dextran-70 (HSD), 7.5% hypertonic saline (HS), 0.9% normal saline - Shock, Traumatic | Phase 3 | Terminated | University of Washington | 895 | 2006-05-01 | 2011-03-01 |
Brain Injuries, Traumatic (3) · Brain Injuries (1) · Intracranial Hypertension (1) · Shock (1) · Shock, Septic (1) · Shock, Traumatic (1) · Wounds and Injuries (1)
University of Washington (2) · Direction Centrale du Service de Santé des Armées (1) · Hospital General de Ciudad Real (1) · University of Cincinnati (1)
United States (3) · Canada (2) · France (1) · Spain (1)
Myron L Weisfeldt, MD (2) · Lori Shutter, MD (1)
PMID 25072443, PMID 20924011, PMID 21178763
U01HL077863 (2)