5 completed, 2 not yet recruiting, 1 withdrawn. 8 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 5, Not yet recruiting 2, Withdrawn 1 |
Follow Saccharin: new trials by email Literature Review of Saccharin trials Research Report on Saccharin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-Term Effects of Sucralose and Saccharin on Blood Sugar and Gut Microbiota in Type 2 Diabetes Sucralose, Saccharin, Placebo (Calcium Carbonate) - Type 2 Diabetes Mellitus (T2DM) | Not applicable | Not yet recruiting | National University of Malaysia | 33 | 2026-01-30 | 2025-12-10 |
| Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic Subjects Saccharin, Sucralose, Erythritol - Prediabetic State, Metabolic Syndrome | Not applicable | Not yet recruiting | Charite University, Berlin, Germany | 80 | 2026-01-05 | 2026-01-29 |
| The Acute Effect of D-allulose Consumption on Postprandial Glycaemia D-Allulose, Sodium Saccharin - Sugar; Blood, High | Not applicable | Completed | University of Nottingham | 12 | 2023-09-11 | 2024-06-25 |
| Microbiome and Non-caloric Sweeteners in Humans Glucose, Aspartame, Sucralose - Glucose Intolerance, Glucose, Low Blood | Not applicable | Completed | Weizmann Institute of Science | 120 | 2017-02-19 | 2021-08-04 |
| Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors Oral Glucose Tolerance Test (OGTT), Assessment of dietary compliance, Stool sampling - Obesity | Not applicable | Completed | AdventHealth Translational Research Institute | 102 | 2017-01-26 | 2023-02-02 |
| On the Impact of Common Sweetening Agents on Glucose Regulation, Cognitive Functioning and Gut Microbiota Sucrose, Stevia glycosides, saccharin - Healthy Subjects | Not applicable | Completed | Lund University | 39 | 2015-10-01 | 2016-06-23 |
| Effect of Stevioside in Postpandrial Glucose in Healthy Adults Purified extract of Rebaudina Stevia-Stevioside, Sodium saccharin - Hyperglycemia, Hypertension | Not applicable | Withdrawn | Basque Health Service | 2013-09-01 | 2015-09-09 | |
| SEGATROM: Sensory and Gastrointestinal Impact of Taste Receptor Variants on Human Metabolism and Nutrition sweet block, bitter block, umami-block - Disorder of Glucose Regulation | Not applicable | Completed | German Institute of Human Nutrition | 97 | 2011-12-01 | 2020-06-24 |
Diabetes Mellitus, Type 2 (2) · Hyperglycemia (2) · Cardiovascular Diseases (1) · Diabetes Mellitus (1) · Glucose Intolerance (1) · Hypertension (1) · Insulin Resistance (1) · Metabolic Syndrome (1) · Obesity (1) · Prediabetic State (1) · Thrombophilia (1) · Thrombosis (1)
AdventHealth Translational Research Institute (1) · Basque Health Service (1) · Charite University, Berlin, Germany (1) · German Institute of Human Nutrition (1) · Lund University (1) · National University of Malaysia (1) · University of Nottingham (1) · Weizmann Institute of Science (1)
Germany (1) · Israel (1) · Malaysia (1) · Spain (1) · Sweden (1) · United Kingdom (1) · United States (1)
Andreas FH Peiffer, Prof (1) · Anne Nilsson, PhD (1) · Eran Elinav (1) · Liz Simpson, PhD (1) · Richard Pratley, MD (1)
PMID 33431052, PMID 20078374, PMID 25231862, PMID 26721819, PMID 30602577, PMID 31258108, PMID 33171964, PMID 33346905, PMID 35208888, PMID 35242721, PMID 35987213, PMID 36857956, PMID 41370820