5 completed, 1 terminated. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 5, Terminated 1 |
Follow Riluzole: new trials by email Literature Review of Riluzole trials Research Report on Riluzole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High Inflammation Riluzole, Placebo - Inflammation, Fatigue | Phase 4 | Completed | Emory University | 30 | 2016-04-01 | 2021-04-14 |
| Developing New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotransmission D-serine, Riluzole, Placebo - Tourette Syndrome | Phase 4 | Completed | Johns Hopkins University | 39 | 2009-11-01 | 2018-01-30 |
| Riluzole in Fragile X Syndrome Riluzole - Fragile X Syndrome | Phase 4 | Completed | Indiana University | 6 | 2009-04-01 | 2017-04-18 |
| Research Study for Major Depressive Disorder: Investigation of Glutamate Medications Lamotrigine, Ketamine, Riluzole - Major Depression | Phase 4 | Completed | Baylor College of Medicine | 26 | 2006-12-01 | 2019-07-31 |
| Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes Memantine, Riluzole - Mood, Memory Deficit | Phase 4 | Terminated | University of Texas Southwestern Medical Center | 20 | 2005-11-01 | 2013-04-23 |
| CARE Canadian ALS Riluzole Evaluation Riluzole - Amyotrophic Lateral Sclerosis | Phase 4 | Completed | Sanofi | 414 | 2001-01-01 | 2007-10-11 |
Amyotrophic Lateral Sclerosis (1) · Behavior (1) · Cognitive Dysfunction (1) · Depressive Disorder, Major (1) · Fatigue (1) · Fragile X Syndrome (1) · Inflammation (1) · Memory Disorders (1) · Tics (1) · Tourette Syndrome (1)
Baylor College of Medicine (1) · Emory University (1) · Indiana University (1) · Johns Hopkins University (1) · Sanofi (1) · University of Texas Southwestern Medical Center (1)
United States (5) · Canada (1)
Andrew H Miller, MD (1) · Craig A. Erickson, MD (1) · Harvey S Singer, MD (1) · Laurent-Didier Jacobs (1) · Sanjay Mathew, MD (1) · Sherwood Brown (1)
PMID 19288975, PMID 19545857, PMID 21059347, PMID 25271445
M01RR000071 (1), R34MH085844 (1)