56 completed, 14 terminated, 7 unknown, 6 withdrawn. 21 Phase 2, 20 Phase 1, 4 Not applicable, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Completed 13, Terminated 8 |
| Phase 1 | 20 | Completed 12, Terminated 6, Withdrawn 2 |
| Not applicable | 4 | Completed 4 |
| Early Phase 1 | 1 | Withdrawn 1 |
Follow reverse transcriptase-polymerase chain reaction: new trials by email Literature Review of reverse transcriptase-polymerase chain reaction trials Research Report on reverse transcriptase-polymerase chain reaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer cholecalciferol, biopsy, protein expression analysis - Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum | Early Phase 1 | Withdrawn | Case Comprehensive Cancer Center | 2012-04-01 | 2014-01-17 | |
| Studying Genes in Samples From Younger Patients With Ovarian or Testicular Sex Cord Stromal Tumors RNA analysis, gene expression analysis, mutation analysis - Childhood Germ Cell Tumor, Leydig Cell Tumor | Completed | Children's Oncology Group | 50 | 2012-04-01 | 2016-07-14 | |
| Studying Biomarker Expression in Samples From Patients With Down Syndrome and Acute Myeloid Leukemia or Other Transient Myeloproliferative Disorder RNA analysis, reverse transcriptase-polymerase chain reaction, laboratory biomarker analysis - Leukemia | Completed | Children's Oncology Group | 60 | 2012-02-01 | 2016-05-17 | |
| Studying Biomarkers in Samples From Younger Patients With Wilms Tumor gene expression analysis, proteomic profiling, reverse transcriptase-polymerase chain reaction - Kidney Cancer | Completed | Children's Oncology Group | 20 | 2012-02-01 | 2016-05-18 | |
| Biomarkers in Patients With Rhabdomyosarcoma DNA methylation analysis, fluorescence in situ hybridization, gene expression analysis - Sarcoma | Completed | Children's Oncology Group | 20 | 2011-10-01 | 2016-05-19 | |
| Identification of Genes That Predict Local Recurrence in Samples From Patients With Breast Cancer Treated on NSABP-B-28 RNA analysis, gene expression analysis, microarray analysis - Breast Cancer | Unknown | NSABP Foundation Inc | 1300 | 2011-10-01 | 2015-05-08 | |
| Hsp90 Inhibitor STA-9090 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy Hsp90 inhibitor STA-9090, laboratory biomarker analysis, polymerase chain reaction - Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer | Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 18 | 2011-01-01 | 2018-09-18 |
| Azadirachta Indica in Treating Patients With Chronic Lymphocytic Leukemia laboratory biomarker analysis, western blotting, gene expression analysis - Refractory Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2010-12-01 | 2014-01-13 | |
| Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia DNA methylation analysis, gene expression analysis, microarray analysis - Leukemia | Completed | Children's Oncology Group | 32 | 2010-11-01 | 2016-05-19 | |
| RNA Biomarkers in Tissue Samples From Infants With Acute Myeloid Leukemia RNA analysis, nucleic acid sequencing, reverse transcriptase-polymerase chain reaction - Leukemia | Completed | Children's Oncology Group | 20 | 2010-10-01 | 2016-05-17 | |
| Panobinostat and Fluorouracil Followed By Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer Who Did Not Respond to Previous Fluorouracil-Based Chemotherapy panobinostat, fluorouracil, leucovorin calcium - Recurrent Colon Cancer, Recurrent Rectal Cancer | Phase 1 | Terminated | University of Southern California | 7 | 2010-10-01 | 2015-05-27 |
| Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer letrozole, panobinostat, RNA analysis - Breast Cancer | Phase 1 / Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 28 | 2010-09-01 | 2017-06-27 |
| Studying Genes in Samples From Younger Patients With Acute Lymphoblastic Leukemia DNA analysis, fluorescence in situ hybridization, gene expression analysis - Leukemia | Unknown | Eastern Cooperative Oncology Group | 400 | 2010-08-01 | 2013-07-10 | |
| Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer RNA analysis, reverse transcriptase-polymerase chain reaction, enzyme-linked immunosorbent assay - Endometrial Cancer | Unknown | Gynecologic Oncology Group | 865 | 2010-07-01 | 2011-04-29 | |
| Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma azacitidine, lenalidomide, dexamethasone - Refractory Multiple Myeloma | Phase 1 / Phase 2 | Completed | Case Comprehensive Cancer Center | 45 | 2010-06-01 | 2020-11-16 |
| Obatoclax Mesylate in Samples From Young Patients With Acute Myeloid Leukemia gene expression analysis, microarray analysis, protein expression analysis - Leukemia | Completed | Children's Oncology Group | 50 | 2010-06-01 | 2016-05-18 | |
| Biomarkers in Tissue Samples From Patients With Stage I or Stage III Endometrial Cancer RNA analysis, microarray analysis, reverse transcriptase-polymerase chain reaction - Endometrial Cancer | Unknown | Gynecologic Oncology Group | 100 | 2010-05-01 | 2010-06-22 | |
| Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor DNA methylation analysis, gene expression analysis, microarray analysis - Clear Cell Sarcoma of the Kidney, Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Completed | Children's Oncology Group | 185 | 2010-05-01 | 2016-05-19 | |
| DNA Biomarkers in Samples From Patients With Osteosarcoma and Healthy Volunteers DNA analysis, RNA analysis, fluorescence in situ hybridization - Sarcoma | Completed | Children's Oncology Group | 90 | 2010-04-01 | 2016-05-18 | |
| Biomarkers in Tissue Samples From Patients With Ductal Breast Carcinoma in Situ RNA analysis, gene expression analysis, reverse transcriptase-polymerase chain reaction - Breast Cancer | Completed | ECOG-ACRIN Cancer Research Group | 500 | 2010-03-05 | 2017-05-17 |
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Leukemia (17) · Breast Neoplasms (13) · Colonic Neoplasms (7) · Leukemia, Myeloid, Acute (7) · Rectal Neoplasms (7) · Colorectal Neoplasms (6) · Carcinoma, Non-Small-Cell Lung (5) · Head and Neck Neoplasms (5) · Lung Neoplasms (5) · Prostatic Neoplasms (5) · Congenital Abnormalities (4) · Kidney Neoplasms (4) · Multiple Myeloma (4) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (4) · Sarcoma (4)
Children's Oncology Group (13) · City of Hope Medical Center (9) · Alliance for Clinical Trials in Oncology (6) · Case Comprehensive Cancer Center (5) · Mayo Clinic (4) · Roswell Park Cancer Institute (4) · ECOG-ACRIN Cancer Research Group (3) · Barbara Ann Karmanos Cancer Institute (2) · Eastern Cooperative Oncology Group (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Gynecologic Oncology Group (2) · Memorial Sloan Kettering Cancer Center (2) · NSABP Foundation Inc (2) · OHSU Knight Cancer Institute (2) · SWOG Cancer Research Network (2)
United States (46) · Belgium (2) · Canada (1) · Ireland (1)
Afshin Dowlati, MD (1) · Ahmad Awada, MD, PhD (1) · Amy Heerema-McKenney, MD (1) · Angela Davies, MD (1) · Anthony Stein, MD (1) · Antonio Omuro, MD (1) · Asher Chanan-Khan (1) · Bach Ardalan, MD (1) · Balazs Halmos, MD (1) · Barbara Murphy, MD (1) · Bhaumik B. Patel, MD (1) · Brian J. Davis, M.D. (1) · Brian Rini (1) · Carlo M. Croce, MD (1) · Caroline Y. Hu, MD (1)
PMID 11882819, PMID 14654545, PMID 15829324, PMID 18090584, PMID 18799354, PMID 20442368, PMID 21258083, PMID 22989664, PMID 23243055, PMID 24099865, PMID 24383844, PMID 25527568, PMID 26774555, PMID 27217450, PMID 31375516, PMID 34162404, PMID 34847232, PMID 35135810, PMID 36823396, PMID 37196637, PMID 38017103, PMID 38702786, PMID 39283025
P30CA033572 (6), P30CA015083 (3), U10CA031946 (3), P30CA008748 (2), P30CA036727 (2), P30CA043703 (2), P30CA068485 (2), U10CA032102 (2), P01HL048546 (1), P30CA016086 (1), P30CA023074 (1), P30CA072720 (1), P30CA093373 (1), P50CA091956 (1), P50CA107399 (1)