11 completed, 3 unknown, 2 withdrawn. 7 Not applicable, 3 Early Phase 1, 3 Phase 2, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Withdrawn 2 |
| Early Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow retinol palmitate: new trials by email Literature Review of retinol palmitate trials Research Report on retinol palmitate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study Vitamin A palmitate - Choroideremia | Not applicable | Withdrawn | Duke University | 2023-05-01 | 2023-06-29 | |
| Vitamin A and Azithromycin for Acne Vulgaris Vitamin A, Azithromycin - Acne Vulgaris | Early Phase 1 | Unknown | Manchanda Medical Clinic | 30 | 2021-04-01 | 2021-02-25 |
| Retinyl Palmitate-loaded Ethosomes in Acne Vulgaris retinyl palmitate, Tretinoin - Facial Acne Vulgaris | Phase 2 | Completed | Assiut University | 20 | 2020-01-06 | 2022-11-14 |
| Vitamin A Palmitate Supplementation in Patients With Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation Vitamin A Palmitate - Reticular Pseudodrusen (RPD), Age-Related Macular Degeneration | Early Phase 1 | Completed | National Eye Institute (NEI) | 9 | 2018-05-14 | 2025-04-16 |
| Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation Vitamin A palmitate - AMD | Early Phase 1 | Completed | National Eye Institute (NEI) | 8 | 2018-04-20 | 2025-04-15 |
| Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCD retinyl palmitate - Sickle Cell Anemia in Children, Vitamin A Deficiency in Children | Not applicable | Completed | Children's Hospital of Philadelphia | 42 | 2015-10-02 | 2018-08-16 |
| Effect of Daily Consumption of Orange Maize on Breast Milk Retinol in Lactating Zambian Women white maize and a corn oil capsule, orange maize and a corn oil capsule, white maize and a vitamin A capsule - Vitamin A Deficiency | Not applicable | Completed | University of California, Davis | 149 | 2013-10-01 | 2015-01-26 |
| Effect of Small Daily Doses of B-carotene on Breast Milk Retinol b-carotene, retinyl palmitate, placebo - Vitamin A Status | Not applicable | Completed | University of California, Davis | 85 | 2013-01-01 | 2015-06-11 |
| Efficacy of Newborn Vitamin A Supplementation in Improving Immune Function retinyl palmitate, Placebo - Vitamin A Deficiency | Not applicable | Completed | USDA, Western Human Nutrition Research Center | 300 | 2012-01-01 | 2014-08-26 |
| Effect of Vitamin A Supplementation on Immune Responses in Human Neonates Vitamin A (retinyl palmitate). - Vitamin A Deficiency | Phase 2 | Unknown | London School of Hygiene and Tropical Medicine | 200 | 2011-11-01 | 2012-11-14 |
| Impact of Vitamin A on RAR Gene Expression in Multiple Sclerosis Dietary Supplement: vitamin A, placebo - Relapsing Remitting Multiple Sclerosis | Phase 4 | Unknown | Tehran University of Medical Sciences | 20 | 2010-02-01 | 2012-10-12 |
| Impact of Vitamin A Supplementation on Immune System in Multiple Sclerosis Patients Vitamin A, Placebo - Relapsing Remitting Multiple Sclerosis | Phase 4 | Completed | Tehran University of Medical Sciences | 36 | 2009-10-01 | 2014-03-14 |
| Vitamin A Supplementation for Modulation of Mycobacterium Tuberculosis Immune Responses in Latent Tuberculosis Vitamin A, Vitamin A placebo - Latent Tuberculosis Infection | Not applicable | Withdrawn | Medical Research Council Unit, The Gambia | 2009-07-01 | 2015-04-09 | |
| Relative-dose-response Test (RDR) Adaptation for Chronic Liver Disease retinyl palmitate (UNICEF, Melbourne, Australia) - Chronic Liver Disease | Not applicable | Completed | Universidade Federal do Rio de Janeiro | 178 | 2007-10-01 | 2012-07-06 |
| Vitamin A Supplementation in Newborns Study Vitamin A - Infant, Newborn | Phase 3 | Completed | Johns Hopkins Bloomberg School of Public Health | 14035 | 1998-06-01 | 2017-03-03 |
| Single-dose Postpartum Vitamin A Supplementation of Mothers and Neonates Vitamin A (retinyl palmitate) - Vitamin A Deficiency, HIV | Phase 2 | Completed | Johns Hopkins Bloomberg School of Public Health | 28220 | 1997-11-01 | 2022-10-18 |
Vitamin A Deficiency (4) · Acne Vulgaris (2) · Multiple Sclerosis (2) · Multiple Sclerosis, Relapsing-Remitting (2) · Breast Feeding (1) · Callosities (1) · Choroideremia (1) · Fibrosis (1) · Hepatitis B (1) · Latent Tuberculosis (1) · Macular Degeneration (1) · Malnutrition (1) · Tetanus (1) · Tuberculosis (1)
Johns Hopkins Bloomberg School of Public Health (2) · National Eye Institute (NEI) (2) · Tehran University of Medical Sciences (2) · University of California, Davis (2) · Assiut University (1) · Children's Hospital of Philadelphia (1) · Duke University (1) · London School of Hygiene and Tropical Medicine (1) · Manchanda Medical Clinic (1) · Medical Research Council Unit, The Gambia (1) · USDA, Western Human Nutrition Research Center (1) · Universidade Federal do Rio de Janeiro (1)
United States (5) · Iran (2) · Bangladesh (1) · Brazil (1) · Canada (1) · Egypt (1) · India (1) · The Gambia (1) · Zambia (1)
Emily Y Chew, M.D. (2) · Ali Akbar Saboor Yaraghi, PhD (1) · Charles B. Stephensen, Ph.D. (1) · Gabriela V Chaves, PhD (1) · Ifedayo MO Adetifa, MD FWACP (1) · James M Tielsch, PhD (1) · Jean H Humphrey, ScD (1) · Lakshmi Rahmathullah, MBBS (1) · Marjorie Haskell, PhD (1) · Martin OC Ota, MD FWACP PhD (1) · Sama Bitarafan, MD, PhD student (1) · Sara M Awad, MD (1) · Sima Jafarirad, PhD student (1) · Suzanna LR McDonald, BSc (Hons) MSc PhD (1)
PMID 37315571, PMID 10523553, PMID 11160543, PMID 11303832, PMID 12558331, PMID 12896935, PMID 14608059, PMID 15075545, PMID 15699235, PMID 15795468, PMID 15821396, PMID 16185228, PMID 16247244, PMID 17951487, PMID 18356336, PMID 18532922, PMID 19437315, PMID 19759098, PMID 21164424, PMID 21736776, PMID 22535764, PMID 23868508, PMID 24708735, PMID 24918554, PMID 25269669, PMID 27466608, PMID 30576507, PMID 30674610, PMID 31504694, PMID 32939553, PMID 37468045