115 completed, 12 terminated, 12 unknown, 2 withdrawn. 39 Phase 4, 30 Phase 1, 25 Phase 3, 19 Not applicable, 19 Phase 2.
Follow Raltegravir: new trials by email Literature Review of Raltegravir trials Research Report on Raltegravir
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Research on the Psychological Status of Patients With HIV-1 Infection All kinds of INSTI medications, All kinds of conventional medications - HIV-1-infection, Anxiety Depression | Not yet recruiting | Shanxi Bethune Hospital | 500 | 2025-08-01 | 2025-07-23 | |
| Pregnancy and Neonatal Outcomes Following Antenatal Exposure to Raltegravir: a Pooled Analysis From the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC) Raltegravir - HIV Infections | Unknown | Fondazione Penta UK | 1200 | 2023-02-20 | 2023-03-02 | |
| Combination Antiretroviral Therapy (cART) for PBC Emtricitabine (FTC)/Tenofovir Disoproxil (TDF), Raltegravir, Placebo Oral Capsule [CEBOCAP] - Primary Biliary Cholangitis | Phase 2 | Completed | University of Alberta | 37 | 2021-03-01 | 2024-02-16 |
| Neuropsyquiatric Evolution After Introduction of Raltegravir QD in Substitution of Dolutegravir: NEAR QD Study Raltegravir - HIV Infections | Phase 4 | Unknown | Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud | 50 | 2019-05-01 | 2019-02-15 |
| Safety, Tolerability, and Pharmacokinetics of Raltegravir (MK-0518) in Healthy Japanese Male Participants (MK-0518-851) Raltegravir - Human Immunodeficiency Virus (HIV) Infection | Phase 4 | Completed | Merck Sharp & Dohme LLC | 12 | 2018-09-27 | 2019-10-02 |
| Study With Dual Therapy Including Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) in Virologically Suppressed HIV-1 Infected Patients Experiencing Inconvenience, Toxicity, Negative Impact on Co-morbidities or Risk of Drug-drug Interactions With Their Current Regimen Raltegravir, Lamivudine - HIV Seropositivity, HIV Infections | Phase 3 | Terminated | Judit Pich | 17 | 2018-05-03 | 2025-05-18 |
| Simplification Study of HIV-1 Infected Patients With Virological Suppression Under the Combination of Lamivudine (150 mg BID) Plus Raltegravir (400 mg BID) Switching to Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) : Roll-over Study of the RALAM Raltegravir, Lamivudine - HIV Infections, HIV-1-infection | Phase 3 | Completed | Judit Pich | 33 | 2018-05-02 | 2025-07-18 |
| Effect on Liver Fat and Metabolic Parameters When Switching a Protease Inhibitor or Efavirenz to Raltegravir Raltegravir - HIV Seropositivity, Metabolic Syndrome | Phase 4 | Completed | Helsinki University Central Hospital | 45 | 2018-01-10 | 2021-09-05 |
| Clinical Trial to Evaluate the Effect of Raltegravir Intensification (1.200 mg QD) on the Gut Microbiota of Chronically HIV-1 Infected Subject Over Time: THE RAGTIME STUDY Raltegravir, Placebo, Current ART - HIV | Phase 3 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 61 | 2017-07-28 | 2025-06-17 |
| Population Pharmacokinetics of Antiretroviral in Children Dolutegravir, Raltegravir, Rilpivirine - Minor Patient Treated by One or More Antiretroviral and for Which a Blood Test Has Been Performed | Completed | Assistance Publique - Hôpitaux de Paris | 65 | 2017-06-16 | 2026-04-03 | |
| A Drug Interaction Study to Assess the Pharmacokinetics of Narlaprevir and Antiretroviral Drugs Narlaprevir, Ritonavir, Tenofovir Disoproxil Fumarate - Healthy | Phase 1 | Completed | R-Pharm | 36 | 2017-04-24 | 2019-02-19 |
| Research In Viral Eradication of HIV Reservoirs Combination Antiretroviral Therapy (cART), Raltegravir, Vorinostat - HIV | Phase 2 | Completed | Imperial College London | 60 | 2015-11-27 | 2023-10-23 |
| Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen Raltegravir, PI-based regimen, Atorvastatin - Aging-related Inflammation in HIV-infected Patients | Phase 4 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 42 | 2015-10-15 | 2020-10-29 |
| Antiretroviral Regimens Containing Raltegravir for Prophylaxis of Mother-to-child-transmission of HIV Infection Raltegravir, Lopinavir/Ritonavir - HIV, Pregnancy | Phase 2 / Phase 3 | Terminated | Fundação Bahiana de Infectologia | 33 | 2015-06-01 | 2024-10-15 |
| Effects of Raltegravir Based Regimen on Platelet Reactivity, Platelet-monocyte Aggregation and Immune Activation Raltegravir, Continuation of own regimen - HIV | Phase 4 | Completed | Radboud University Medical Center | 40 | 2015-03-01 | 2019-01-10 |
| Raltegravir-based Antiretroviral Versus Maintaining Any Other Antiretroviral Therapy in HIV Mono-infected Patients Isentress., Continue usual antiretroviral therapy - HIV, Fatty Liver | Phase 4 | Completed | McGill University Health Centre/Research Institute of the McGill University Health Centre | 31 | 2015-03-01 | 2023-10-19 |
| Safety, Tolerance and Pharmacokinetics of Raltegravir-Containing Antiretroviral Therapy in Infants, Children Infected With HIV and TB Raltegravir - HIV Infections, Tuberculosis | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 40 | 2014-11-12 | 2021-11-05 |
| Comparison of Virologic and Immunologic Responses to Raltegravir and Dolutegravir in the Gastrointestinal Tract of HIV-Positive Adults Raltegravir, Dolutegravir, Colonoscopy with biopsy - Human Immunodeficiency Virus | Completed | University of North Carolina, Chapel Hill | 20 | 2014-10-01 | 2018-12-26 | |
| A Retrospective Analysis of Raltegravir Use in Minority HIV Infected Women in Houston, Texas raltegravir - HIV Infection | Unknown | The University of Texas Health Science Center, Houston | 254 | 2014-09-01 | 2017-05-22 | |
| Study in Healthy Volunteers to Investigate the Safety, Tolerability and Pharmacokinetics of VM-1500 VM-1500, Darunavir, Ritonavir - HIV-infection | Phase 1 | Completed | Viriom | 24 | 2014-09-01 | 2018-10-04 |
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