110 completed, 64 recruiting, 61 unknown, 27 active not recruiting. 303 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 303 | Completed 110, Recruiting 64, Unknown 61, Active not recruiting 27, Terminated 23, Not yet recruiting 9, Withdrawn 6, Enrolling by invitation 3 |
Follow Radiotherapy: new trials by email Literature Review of Radiotherapy trials Research Report on Radiotherapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exploratory Study of Low-Dose Whole-Brain Radiation Therapy With HeLaXON 1X in Patients With Mild Alzheimer's Disease Dementia HeLaXON 1X Low-Dose Radiation Therapy, Sham HeLaXON 1X Procedure - Alzheimer Disease | Not applicable | Recruiting | ReadyCure Inc. | 30 | 2026-10-26 | 2026-10-07 |
| Low-Dose Radiotherapy for Painful Knee Osteoarthritis Low-Dose Radiotherapy (LDRT) - Knee Osteoarthritis | Not applicable | Not yet recruiting | Universidad Rey Juan Carlos | 283 | 2026-10-15 | 2026-10-21 |
| Cs-131LDR Brachytherapy for Organ-Preserving Irradiation for Recurrent Cervical and Endometrial Cancer Cesium-131 Low Dose Radiation (LDR) - Gynecologic Cancer | Not applicable | Recruiting | Denise Fabian | 10 | 2026-10-01 | 2026-08-31 |
| External Beam Radiotherapy Combined With Endorectal High-dose-rate Brachytherapy in Elderly and Frail Patients With Rectal Cancer radiotherapy - Rectal Cancer | Not applicable | Not yet recruiting | University Hospital of Cologne | 80 | 2026-09-30 | 2026-05-01 |
| Iparomlimab and Tuvonralimab Combined With Chemotherapy and Bevacizumab as Neoadjuvant Therapy for Locally Advanced Rectal Cancer Iparomlimab and Tuvonralimab（QL-1706）combined with Chemotherapy and Bevacizumab - Locally Advanced Rectal Cancer (LARC), 5-12cm to Anal Verge | Not applicable | Not yet recruiting | Zhejiang University | 56 | 2026-09-01 | 2026-09-15 |
| Radiotherapy for BCG-unresponsive Non-muscle-invasive Carcinoma in Situ (CIS) Bladder Cancer: an Open-label, Single-arm, Multicentre, Phase 2 Study Radiation therapy - Non-Muscle Invasive Bladder Cancer | Not applicable | Recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 50 | 2026-07-23 | 2026-09-11 |
| Reduction of Hematologic Toxicity in Locally Advanced Cervical Cancers radiotherapy with bone marrow contouring - Cervical Cancer by FIGO Stage 2018 | Not applicable | Not yet recruiting | Institut Paoli-Calmettes | 72 | 2026-07-15 | 2026-03-10 |
| Low Dose Radiotherapy for Osteoarthritis Low Dose Radiation Therapy - Osteoarthitis | Not applicable | Recruiting | Abramson Cancer Center at Penn Medicine | 113 | 2026-06-24 | 2026-09-21 |
| Understanding the Feasibility of a Co-designed Pre-radiotherapy Exercise Programme - A Single-arm Study Exercise, radiotherapy - Lung Cancer | Not applicable | Recruiting | Queen's University, Belfast | 30 | 2026-06-02 | 2026-09-08 |
| Neoadjuvant Radiotherapy vs Upfront Surgery in Locally Advanced Proximal Rectal Cancer radiotherapy, surgery - Rectal Adenocarcinoma | Not applicable | Recruiting | Istanbul University | 100 | 2026-04-06 | 2026-09-03 |
| Radiation Therapy (RT) for Parkinson's Disease (PD) Radiation therapy - Parkinson's Disease | Not applicable | Enrolling by invitation | Mayo Clinic | 20 | 2026-01-20 | 2026-06-16 |
| Prospective Clinical Study Comparing PROMS After Adaptive or Conventional Radiotherapy in Prostate Cancer Radiotherapy - Prostate Cancer | Not applicable | Recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 188 | 2026-01-13 | 2026-03-16 |
| Comparison of Efficacy Between De-escalated Surgery and Standard Surgery After Neoadjuvant Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma Radical surgery combined with radiotherapy or chemoradiotherapy, Surgical De-escalation After Neoadjuvant Therapy - Locally Advanced Head and Neck Squamous Cell Carcinoma | Not applicable | Recruiting | Qunxing Li,MD | 60 | 2026-01-12 | 2026-01-27 |
| Biologically-Adapted, Dose-Escalated Radiotherapy for the Treatment of Ewing Sarcoma, BEAR Trial Biospecimen Collection, Chemotherapy, Computed Tomography - Ewing Sarcoma, Round Cell Sarcoma With EWSR1-non-ETS Fusion | Not applicable | Recruiting | Mayo Clinic | 170 | 2025-12-05 | 2026-10-06 |
| Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone Radiofrequency ablation and bone augmentation with radiotherapy, Radiotherapy alone - Spine Metastases, Bone Pain | Not applicable | Recruiting | University of Minnesota | 36 | 2025-12-01 | 2025-12-03 |
| Optical Imaging Scans for the Diagnosis of Skin Cancer in Patients With Lesions Quantitative Oblique Back-Illumination Microscopy, Radiation Therapy - Malignant Skin Neoplasm, Skin Disorder | Not applicable | Recruiting | Emory University | 10 | 2025-10-15 | 2025-12-16 |
| An Evaluation of Dose-escalation for Intrathoracic Tumours Hypofractionated Radiation Therapy, Radiation Therapy - Lung Cancers | Not applicable | Recruiting | Chris Goodman | 141 | 2025-09-03 | 2026-09-14 |
| The Effect of Radiotherapy After Separation Surgery for Spinal Metastases radiotherapy - Spinal Metastases, Spinal Tumor | Not applicable | Recruiting | Wei Xu | 130 | 2025-09-01 | 2026-09-16 |
| The Radiation ProtEction for Dose RedUction in the Cardiac CathEter Lab Study: The REDUCE Trial Radiation - Radiation Exposure, Radiation Exposure to Operator | Not applicable | Recruiting | Liverpool Heart and Chest Hospital NHS Foundation Trust | 100 | 2025-08-29 | 2025-11-24 |
| Partial Breast Re-irradiation for Breast Cancer Radiation Therapy - Breast Cancers | Not applicable | Active not recruiting | University Hospital Heidelberg | 20 | 2025-08-28 | 2026-10-13 |
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Breast Neoplasms (36) · Prostatic Neoplasms (27) · Carcinoma, Non-Small-Cell Lung (14) · Lymphoma (13) · Rectal Neoplasms (12) · Head and Neck Neoplasms (11) · Lung Neoplasms (11) · Neoplasms (10) · Recurrence (10) · Carcinoma, Hepatocellular (9) · Neoplasm Metastasis (9) · Esophageal Neoplasms (8) · Esophageal Squamous Cell Carcinoma (8) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (8) · Brain Neoplasms (7)
Abramson Cancer Center at Penn Medicine (5) · Mayo Clinic (5) · Memorial Sloan Kettering Cancer Center (5) · The Netherlands Cancer Institute (5) · Children's Cancer and Leukaemia Group (4) · M.D. Anderson Cancer Center (4) · Masonic Cancer Center, University of Minnesota (4) · Sichuan Cancer Hospital and Research Institute (4) · Dana-Farber Cancer Institute (3) · Duke University (3) · Fudan University (3) · Institute of Cancer Research, United Kingdom (3) · Jonsson Comprehensive Cancer Center (3) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (3) · NCIC Clinical Trials Group (3)
United States (107) · China (43) · United Kingdom (22) · Canada (16) · Germany (16) · Switzerland (11) · Belgium (10) · France (10) · Netherlands (9) · South Korea (9) · Italy (8) · Sweden (8) · Australia (7) · India (4) · Israel (4)
Ann Barrett (2) · Christopher Kelsey, MD (2) · John Martin, MD (2) · John R. Yarnold, MD, FRCR (2) · Judith M. Ford, MD, PhD (2) · Leonard B. Saltz, MD (2) · Rong Tao, MD (2) · Silvia Formenti, M.D. (2) · Tae Hyun Kim, Ph.D (2) · A. Bapsi Chakravarthy, MD (1) · A. Barratt, MD (1) · Aashish Vyas (1) · Adam Garsa, MD (1) · Adrianne C. Feldstein, MD, MS (1)
PMID 10430262, PMID 10637264, PMID 10813118, PMID 10829040, PMID 10917373, PMID 11535445, PMID 11756581, PMID 11870186, PMID 11981766, PMID 12122555, PMID 12393820, PMID 12622453, PMID 12721240, PMID 14585260, PMID 14616150, PMID 14722039, PMID 15128893, PMID 15466923, PMID 15683818, PMID 16343071, PMID 16861284, PMID 16949180, PMID 16982547, PMID 17000941, PMID 17166637, PMID 17334475, PMID 17690894, PMID 17882490, PMID 18056195, PMID 18172187, PMID 18640307, PMID 19070891, PMID 19527368, PMID 19727846, PMID 19766264, PMID 19936817, PMID 20197669, PMID 20231127, PMID 2032882, PMID 20375833, PMID 20379145, PMID 20395062, PMID 20590903, PMID 20638196, PMID 2080048, PMID 21061074, PMID 2119459, PMID 21636711, PMID 21809989, PMID 22177878
2017 (2), P30CA014089 (2), U10CA098543 (2), 2005 (1), 2023 (1), P01CA021239 (1), P01CA030206 (1), P30CA006516 (1), P30CA006927 (1), P30CA008748 (1), P30CA012197 (1), P30CA016672 (1), P30CA033572 (1), P30CA056036 (1), P30CA068485 (1)