19 completed. 19 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 19 | Completed 19 |
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 1 | Completed 1 |
Follow protein expression analysis: new trials by email Literature Review of protein expression analysis trials Research Report on protein expression analysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer bevacizumab, cetuximab, fluorouracil - Colorectal Cancer | Phase 2 / Phase 3 | Completed | Medical Research Council | 3240 | 2009-07-01 | 2013-12-19 |
| CLL-Irl Study. CTRIAL-IE (ICORG) 07-01, V7 pegfilgrastim, rituximab, cyclophosphamide - Leukemia | Phase 2 | Completed | Cancer Trials Ireland | 52 | 2008-08-18 | 2025-07-08 |
| Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer carboplatin, paclitaxel albumin-stabilized nanoparticle formulation, protein expression analysis - Lung Cancer | Phase 2 | Completed | Greg Otterson | 63 | 2008-08-14 | 2018-04-02 |
| Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer rucaparib (CO-338; formally AG-014699 or PF-01367338), protein expression analysis, western blotting - brca1 Mutation Carrier, brca2 Mutation Carrier | Phase 2 | Completed | Cancer Research UK | 78 | 2007-12-01 | 2016-05-24 |
| Erlotinib Hydrochloride With or Without Celecoxib in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer erlotinib hydrochloride, celecoxib, placebo - Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer | Phase 2 | Completed | City of Hope Medical Center | 107 | 2007-11-01 | 2017-03-29 |
| Proteomic Profiling in Predicting Response in Patients Receiving Erlotinib for Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer bevacizumab, carboplatin, erlotinib hydrochloride - Lung Cancer | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 116 | 2007-10-01 | 2017-06-08 |
| Gemcitabine and Oxaliplatin in Treating Patients With Pancreatic Cancer That Can Be Removed By Surgery gemcitabine hydrochloride, oxaliplatin, protein expression analysis - Pancreatic Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 39 | 2007-10-01 | 2017-03-16 |
| Fluorouracil, Oxaliplatin, and Leucovorin in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction Cancer fluorouracil, leucovorin calcium, oxaliplatin - Gastric Cancer | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 33 | 2007-08-01 | 2012-11-01 |
| Nelfinavir, Radiation Therapy, Cisplatin, and Etoposide in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery cisplatin, etoposide, nelfinavir mesylate - Lung Cancer | Phase 1 / Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 55 | 2007-06-01 | 2020-04-24 |
| Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma temozolomide, protein expression analysis, reverse transcriptase-polymerase chain reaction - Brain and Central Nervous System Tumors | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 47 | 2007-06-01 | 2016-02-29 |
| Floxuridine and Dexamethasone as a Hepatic Arterial Infusion and Bevacizumab in Treating Patients With Primary Liver Cancer That Cannot be Removed by Surgery bevacizumab, dexamethasone, floxuridine - Liver Cancer | Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 22 | 2007-05-09 | 2024-12-10 |
| Laboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-Small Cell Lung Cancer That Did Not Respond to Previous Treatment erlotinib hydrochloride, gene expression analysis, protein expression analysis - Lung Cancer | Phase 2 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 40 | 2006-09-01 | 2010-08-09 |
| Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women) therapeutic autologous dendritic cells, aromatase inhibition therapy, cyclophosphamide - Breast Cancer | Phase 2 | Completed | University of Nebraska | 17 | 2006-05-01 | 2023-09-29 |
| Bevacizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma bevacizumab, gene expression analysis, protein expression analysis - Multiple Myeloma and Plasma Cell Neoplasm | Phase 2 | Completed | Mayo Clinic | 42 | 2006-04-01 | 2011-05-11 |
| ONTAK® in Treating Patients With Advanced Breast Cancer That Did Not Respond to Previous Treatment ONTAK, flow cytometry, immunohistochemistry staining method - Male Breast Cancer, Recurrent Breast Cancer | Phase 1 / Phase 2 | Completed | University of Washington | 15 | 2005-09-01 | 2018-12-05 |
| Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer filgrastim, pegfilgrastim, rituximab - Leukemia, Lymphoma | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 50 | 2005-07-01 | 2016-05-12 |
| Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors bortezomib, pemetrexed disodium, gene expression analysis - Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Completed | University of California, Davis | 27 | 2005-03-01 | 2018-10-31 |
| Erlotinib in Treating Patients With Breast Cancer That Can Be Removed by Surgery erlotinib hydrochloride, TUNEL assay, protein expression analysis - Breast Cancer | Phase 2 | Completed | Vanderbilt-Ingram Cancer Center | 50 | 2002-08-01 | 2012-09-05 |
| Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer cisplatin, docetaxel, fluorouracil - Head and Neck Cancer | Phase 2 | Completed | City of Hope Medical Center | 31 | 2000-06-07 | 2025-02-19 |
Carcinoma, Non-Small-Cell Lung (6) · Lung Neoplasms (5) · Breast Neoplasms (4) · Leukemia (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Adenocarcinoma of Lung (1) · Adenocarcinoma, Bronchiolo-Alveolar (1) · Astrocytoma (1) · Brain Neoplasms (1) · Breast Neoplasms, Male (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Ovarian Epithelial (1) · Central Nervous System Neoplasms (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1)
Memorial Sloan Kettering Cancer Center (4) · Vanderbilt-Ingram Cancer Center (3) · City of Hope Medical Center (2) · Abramson Cancer Center at Penn Medicine (1) · Cancer Research UK (1) · Cancer Trials Ireland (1) · Greg Otterson (1) · Mayo Clinic (1) · Medical Research Council (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of California, Davis (1) · University of Nebraska (1) · University of Washington (1)
United States (15) · United Kingdom (2) · Ireland (1)
Amit Maity (1) · Andrew D. Zelenetz, MD, PhD (1) · Angela Davies, MD (1) · Antonio Omuro, MD (1) · Carlos L. Arteaga, MD (1) · Charles M. Rudin, MD, PhD (1) · David Carbone, M.D., Ph.D. (1) · Eileen O'Reilly, MD (1) · Elisabeth Vandenberghe, MD (1) · Elizabeth C Reed, MD (1) · Gregory A. Otterson, MD (1) · Karen Reckamp (1) · Kenneth H Cowan, MD, PhD (1) · Laura W. Goff, MD (1) · Lupe Salazar (1)
PMID 18090584, PMID 21677464, PMID 23243055, PMID 24901360, PMID 25057165, PMID 26123189, PMID 28925785, PMID 31319977, PMID 31436839, PMID 35135810
P30CA068485 (2), 2008 (1), P30CA006973 (1), P30CA008748 (1), P30CA015083 (1), P30CA033572 (1), P30CA036727 (1), P50CA098131 (1), R01CA080195 (1)