15 completed, 4 terminated, 2 unknown. 21 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 21 | Completed 15, Terminated 4, Unknown 2 |
| Phase 2 | 6 | Completed 4, Terminated 1, Unknown 1 |
Follow protein expression analysis: new trials by email Literature Review of protein expression analysis trials Research Report on protein expression analysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma olaparib, temozolomide, gene expression analysis - Brain and Central Nervous System Tumors | Phase 1 | Completed | Cancer Research UK | 34 | 2011-07-01 | 2018-02-05 |
| Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain Metastases bafetinib, microdialysis, pharmacological study - Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma | Phase 1 | Completed | City of Hope Medical Center | 7 | 2010-12-01 | 2018-04-17 |
| Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma erlotinib hydrochloride, isotretinoin, laboratory biomarker analysis - Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma | Phase 1 | Terminated | Wake Forest University Health Sciences | 5 | 2010-05-01 | 2018-08-01 |
| Aspirin Mouthwash in Treating Patients With Oral Leukoplakia acetylsalicylic acid, gene expression analysis, protein expression analysis - Precancerous Condition | Phase 1 | Completed | Institute of Head and Neck Studies and Education, United Kingdom | 40 | 2010-02-01 | 2013-08-12 |
| Panobinostat and Epirubicin in Treating Patients With Metastatic Malignant Solid Tumors epirubicin hydrochloride, panobinostat, gene expression analysis - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | University of California, San Francisco | 40 | 2009-09-13 | 2017-03-24 |
| Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast vorinostat, protein expression analysis, immunohistochemistry staining method - Breast Cancer | Phase 1 | Completed | University of California, San Francisco | 17 | 2009-07-01 | 2017-08-07 |
| PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma VEGF inhibitor PTC299, gene expression analysis, polymerase chain reaction - Kaposi's Sarcoma | Phase 1 / Phase 2 | Terminated | AIDS Malignancy Consortium | 17 | 2008-09-01 | 2018-06-06 |
| Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous Leukemia imatinib mesylate, panobinostat, polymerase chain reaction - Leukemia | Phase 1 | Completed | City of Hope Medical Center | 9 | 2008-05-01 | 2014-08-15 |
| Cidofovir in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer Who Are Receiving Chemotherapy and Radiation Therapy carboplatin, cidofovir, protein expression analysis - Cervical Cancer, Precancerous Condition | Phase 1 | Unknown | Gustave Roussy, Cancer Campus, Grand Paris | 24 | 2008-04-01 | 2010-01-28 |
| Sorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or Leg melphalan, sorafenib tosylate, gene expression analysis - Melanoma (Skin) | Phase 1 | Completed | Duke University | 20 | 2007-10-01 | 2015-03-06 |
| Nelfinavir, Radiation Therapy, Cisplatin, and Etoposide in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery cisplatin, etoposide, nelfinavir mesylate - Lung Cancer | Phase 1 / Phase 2 | Completed | Abramson Cancer Center at Penn Medicine | 55 | 2007-06-01 | 2020-04-24 |
| Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer recombinant interleukin-7, gene expression analysis, polymerase chain reaction - Kidney Cancer, Melanoma (Skin) | Phase 1 | Terminated | Cytheris SA | 9 | 2007-05-01 | 2012-10-18 |
| Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme R-(-)-gossypol acetic acid, temozolomide, gene expression analysis - Brain and Central Nervous System Tumors | Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 50 | 2007-02-01 | 2012-05-03 |
| Riluzole in Treating Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery riluzole, protein expression analysis, reverse transcriptase-polymerase chain reaction - Melanoma (Skin) | Phase 1 | Terminated | University of Medicine and Dentistry of New Jersey | 15 | 2007-02-01 | 2009-12-11 |
| AEG35156 and Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Solid Tumors AEG35156, docetaxel, protein expression analysis - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | NCIC Clinical Trials Group | 27 | 2006-07-27 | 2023-08-04 |
| Celecoxib in Treating Patients With Head and Neck Cancer That Can Be Removed By Surgery celecoxib, microarray analysis, protein expression analysis - Head and Neck Cancer | Phase 1 / Phase 2 | Unknown | Centre Hospitalier Universitaire Vaudois | 24 | 2006-06-01 | 2010-12-24 |
| ONTAK® in Treating Patients With Advanced Breast Cancer That Did Not Respond to Previous Treatment ONTAK, flow cytometry, immunohistochemistry staining method - Male Breast Cancer, Recurrent Breast Cancer | Phase 1 / Phase 2 | Completed | University of Washington | 15 | 2005-09-01 | 2018-12-05 |
| Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer filgrastim, pegfilgrastim, rituximab - Leukemia, Lymphoma | Phase 1 / Phase 2 | Completed | Memorial Sloan Kettering Cancer Center | 50 | 2005-07-01 | 2016-05-12 |
| Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors bortezomib, pemetrexed disodium, gene expression analysis - Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 / Phase 2 | Completed | University of California, Davis | 27 | 2005-03-01 | 2018-10-31 |
| Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer pNGVL3-hICD vaccine, sargramostim, flow cytometry - HER2-positive Breast Cancer, Stage III Ovarian Epithelial Cancer | Phase 1 | Completed | University of Washington | 66 | 2001-10-01 | 2025-04-06 |
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Glioblastoma (4) · Gliosarcoma (4) · Brain Neoplasms (3) · Breast Neoplasms (3) · Melanoma (3) · Astrocytoma (2) · Carcinoma, Non-Small-Cell Lung (2) · Central Nervous System Neoplasms (2) · Glioma (2) · Leukemia (2) · Lung Neoplasms (2) · Oligodendroglioma (2) · Precancerous Conditions (2) · AIDS-related Kaposi sarcoma (1) · Basal Cell Nevus Syndrome (1)
City of Hope Medical Center (2) · University of California, San Francisco (2) · University of Washington (2) · AIDS Malignancy Consortium (1) · Abramson Cancer Center at Penn Medicine (1) · Cancer Research UK (1) · Centre Hospitalier Universitaire Vaudois (1) · Cytheris SA (1) · Duke University (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · Institute of Head and Neck Studies and Education, United Kingdom (1) · Memorial Sloan Kettering Cancer Center (1) · NCIC Clinical Trials Group (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1) · University of California, Davis (1)
United States (15) · United Kingdom (2) · Canada (1) · France (1) · Switzerland (1)
Allen E. Bale, MD (1) · Amit Maity (1) · Andrew D. Zelenetz, MD, PhD (1) · Angela Davies, MD (1) · Anthony Chalmers, Prof (1) · Douglas S. Tyler, MD (1) · Eric Deutsch, MD (1) · Francois Luthi, MD (1) · Gerald Batist, MD (1) · Glenn Lesser (1) · Hisham Mehanna, MD (1) · James S. Goydos, MD (1) · Jana Portnow (1) · John Fiveash, MD (1) · Laura Esserman, MD, MBA (1)
PMID 18090584, PMID 23380277, PMID 26903311, PMID 31436839, PMID 36326756
P30CA033572 (1), P30CA072720 (1), U01CA062475 (1), U01CA121947 (1)