17 completed, 5 not yet recruiting, 4 recruiting, 3 unknown. 23 Not applicable, 6 Phase 4, 2 Phase 3.
Follow Propofol group: new trials by email Literature Review of Propofol group trials Research Report on Propofol group
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Remimazolam vs Propofol for Long-Term Sedation in Mechanically Ventilated ICU Patients Remimazolam group, Propofol group - Long-term Sedation for Mechanical Ventilation, Critically Ill Intensive Care Unit Patients | Phase 3 | Not yet recruiting | Sun Yat-sen University | 274 | 2026-10-20 | 2026-10-21 |
| Effects of Low-Dose Ketamine Added to Propofol Sedation During Colonoscopy Propofol group, Propofol + Ketamine - Colonoscopy Procedures, Sedation | Not applicable | Not yet recruiting | Ankara Etlik City Hospital | 100 | 2026-09-14 | 2026-09-09 |
| Effect of Ciprofol Injection on Postoperative Cognitive Function Ciprofol group, Propofol group - Postoperative Cognitive Dysfunction | Phase 4 | Active not recruiting | The Second Affiliated Hospital of Chongqing Medical University | 298 | 2026-06-01 | 2026-06-29 |
| The Influence of Prone Position for Spinal Surgery on Visual Acuity Desflurane Group, Propofol Group - Vision; Disorder, Loss | Not applicable | Not yet recruiting | University Hospital Hradec Kralove | 60 | 2025-11-28 | 2024-05-10 |
| Dynamic Effects of Different Anesthetic Agents on the Immune Function of Healthy Volunteers Propofol group, Sevoflurane group, Ciprofol group - Immune System | Not applicable | Enrolling by invitation | Henan Provincial People's Hospital | 80 | 2025-11-21 | 2026-02-04 |
| Desflurane vs. Propofol for Cardiac Anesthesia Desflurane group, Propofol group - Cardiac Surgery, Coronary Artery Bypass Grafting | Phase 3 | Recruiting | Xijing Hospital | 3560 | 2025-10-20 | 2025-11-25 |
| Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pediatric Surgery Sevoflurane group, Propofol group - Postoperative Cognitive Dysfunction, Postoperative Delirium | Not applicable | Not yet recruiting | General Hospital of Ningxia Medical University | 200 | 2025-09-15 | 2025-09-25 |
| Effect of Ciprofol on Intraoperative Hypotension in Elderly Patients Receiving Renin-angiotensin System Inhibitors Ciprofol group, Propofol group - Intraoperative Hypotension, Ciprofol | Phase 4 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 140 | 2025-04-10 | 2025-12-30 |
| The Influence of Genetic Polymorphism on Dose- Dependent Analgesic Response and Safety to Propofol in General Anesthesia Propofol Group, Isoflurane Group - Analgesia | Not applicable | Active not recruiting | Superior University | 159 | 2025-04-01 | 2026-04-22 |
| Comparison of Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy Ciprofol group, Propofol group - Adenotonsillectomy, Propofol | Not applicable | Recruiting | Maternal and Child Health Hospital of Hubei Province | 236 | 2025-02-22 | 2025-06-12 |
| Effect of Propofol Versus Remimazolam Intravenous Anesthesia on Respiratory Depression Propofol group, Remimazolam group - Respiratory Depression | Phase 4 | Not yet recruiting | Second Affiliated Hospital of Wenzhou Medical University | 96 | 2025-02-01 | 2025-02-10 |
| Induction Agents in ECT: Effects on Seizure Duration, Quality, and Recovery Propofol group, Thiopental, Ketamine (0.5 mg/kg) - Electroconvulsive Therapy, Anesthesia, General | Not applicable | Completed | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 100 | 2024-07-17 | 2026-05-19 |
| A Low Dose Dexmedetomidine in Sedation Colonoscopy Dexmedetomidine, Propofol - Colonoscopy | Not applicable | Unknown | West China Hospital | 104 | 2024-01-20 | 2024-01-17 |
| Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy Ciprofol group, Propofol group - Ciprofol, Hysteroscopy | Not applicable | Completed | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 124 | 2024-01-01 | 2024-08-21 |
| Cognitive Function in Geriatric Colonoscopy Patients Propofol Group, Dexmedetomidine group - Cognition, Sedation | Completed | Ankara City Hospital Bilkent | 164 | 2023-08-01 | 2026-02-10 | |
| How Are Cognitive Functions Affected by Different Sedation Methods in Geriatric Patients? Dexmedetomidine group, Propofol group - Cognition, Sedation for Gastroenteric Endoscopic Procedure | Completed | Ankara City Hospital Bilkent | 184 | 2023-07-20 | 2024-12-06 | |
| EEG Parameters Between Remimazolam- and Propofol-based Anesthesia propofol group, remimazolam group - Cholecystitis, Acute, Gallbladder Neoplasms | Not applicable | Completed | Yonsei University | 60 | 2023-06-26 | 2023-12-21 |
| Efficacy and Safety of Ciprofol in Laparoscopic Sleeve Gastrectomy Ciprofol, Propofol - Bariatric Surgery | Phase 4 | Completed | The Third People's Hospital of Chengdu | 212 | 2023-01-01 | 2024-08-28 |
| Sevoflurane and Propofol for Botulinum Toxin Injection Sevoflurane, Propofol - Cerebral Palsy | Not applicable | Withdrawn | Yeungnam University College of Medicine | 2022-08-26 | 2023-02-15 | |
| Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy Remimazolam, Propofol group - Anesthetics, Recovery | Phase 4 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 300 | 2022-07-10 | 2022-07-01 |
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Cholecystitis, Acute (2) · Postoperative Cognitive Complications (2) · Acalculous Cholecystitis (1) · Agnosia (1) · Aortic Diseases (1) · Brain Neoplasms (1) · Breast Neoplasms (1) · Cerebral Palsy (1) · Colonic Neoplasms (1) · Emergence Delirium (1) · Frailty (1) · Gallbladder Neoplasms (1) · Heart Valve Diseases (1) · Ischemia (1) · Laryngeal Neoplasms (1)
Konkuk University Medical Center (4) · Ankara City Hospital Bilkent (2) · Yonsei University (2) · Ankara Etlik City Hospital (1) · Dr. Lutfi Kirdar Kartal Training and Research Hospital (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · Gangnam Severance Hospital (1) · General Hospital of Ningxia Medical University (1) · Giresun University (1) · Henan Provincial People's Hospital (1) · Mansoura University (1) · Maternal and Child Health Hospital of Hubei Province (1) · Pamukkale University (1) · Qinghai University (1) · Second Affiliated Hospital of Wenzhou Medical University (1)
China (10) · South Korea (9) · Turkey (Türkiye) (6) · Canada (1) · Czechia (1) · Egypt (1) · Pakistan (1) · United States (1)
Seong-Hyop Kim, M.D,Ph.D (3) · Bon-Nyeo Koo (2) · Chong Lei, M.D., phd (1) · Filiz Kaya, M.D. (1) · Guangyou Duan (1) · Huacheng Liu (1) · Li Zhou (1) · Mehmet S Ozcan, M.D. (1) · Min Yan (1) · Na Li, MD (1) · Pavel Dostal, MD, Ph.D. (1) · Qiang Wang (1)
PMID 25460022, PMID 31714323, PMID 25692433, PMID 25893178, PMID 29414618, PMID 30618439, PMID 32076394, PMID 33564684, PMID 35346041, PMID 37131126, PMID 38436174, PMID 39193191, PMID 40279265, PMID 40530830, PMID 40705792, PMID 41372755