13 completed, 2 withdrawn, 1 terminated, 1 unknown. 7 Phase 1, 4 Phase 2, 3 Phase 3, 2 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 6, Terminated 1 |
| Phase 2 | 4 | Completed 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 3 | Completed 3 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 2 |
Follow pravastatin sodium: new trials by email Literature Review of pravastatin sodium trials Research Report on pravastatin sodium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Indonesia Pravastatin to Prevent Preeclampsia Study Pravastatin - Pre-Eclampsia | Phase 2 | Unknown | Universitas Airlangga | 280 | 2018-03-01 | 2018-08-28 |
| Statins: A New Therapeutic Option for Treatment of Patients With Endometriosis Pravastatin - Endometriosis | Not applicable | Withdrawn | Dr. Robert F. Casper | 2014-07-01 | 2020-08-28 | |
| Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes pravastatin sodium, idarubicin, cytarabine - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Not applicable | Completed | Fred Hutchinson Cancer Center | 24 | 2013-05-01 | 2017-11-17 |
| Pravastatin for Prevention of Preeclampsia Pravastatin, Placebo - Preeclampsia | Phase 1 | Completed | The University of Texas Medical Branch, Galveston | 48 | 2012-08-01 | 2025-05-04 |
| Effect of HAART Vs. Statin Treatment on Endothelial Function and Inflammation/Coagulation Pravastatin sodium, Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate - HIV-1 Infection | Phase 2 | Withdrawn | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 2011-11-01 | 2016-02-01 | |
| Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia cyclosporine, pravastatin sodium, mitoxantrone hydrochloride - Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Phase 1 / Phase 2 | Terminated | Fred Hutchinson Cancer Center | 6 | 2011-04-01 | 2017-07-02 |
| Effects of Pravastatin on Cholesterol, Inflammation and Cognition in Schizophrenia Pravastatin, Placebo - Schizophrenia, Schizoaffective Disorders | Phase 4 | Completed | Massachusetts General Hospital | 60 | 2010-06-01 | 2014-04-28 |
| Sorafenib Tosylate With or Without Pravastatin in Treating Patients With Liver Cancer and Cirrhosis pravastatin sodium, sorafenib tosylate - Liver Cancer | Phase 3 | Completed | Federation Francophone de Cancerologie Digestive | 323 | 2010-02-01 | 2020-03-30 |
| S0919 Idarubicin, Cytarabine, and Pravastatin in Treating Patients With Relapsed Acute Myeloid Leukemia cytarabine, idarubicin, pravastatin sodium - Leukemia | Phase 2 | Completed | SWOG Cancer Research Network | 115 | 2009-12-10 | 2023-05-03 |
| Etoposide and Cisplatin or Carboplatin as First-Line Chemotherapy With or Without Pravastatin in Treating Patients With Small Cell Lung Cancer carboplatin, cisplatin, etoposide phosphate - Lung Cancer | Phase 3 | Completed | University College, London | 846 | 2007-01-01 | 2014-12-03 |
| Bioequivalence Study of Pravastatin Sodium Tablets 80 mg Under Fasting Conditions Pravastatin Sodium - Healthy | Phase 1 | Completed | Dr. Reddy's Laboratories Limited | 43 | 2002-12-01 | 2010-06-17 |
| Bioequivalence Study of Pravastatin Sodium Tablets 80 mg Under Fed Conditions Pravastatin Sodium - Healthy | Phase 1 | Completed | Dr. Reddy's Laboratories Limited | 24 | 2002-11-01 | 2012-01-13 |
| Pravastatin or Atorvastatin Evaluation and Infection Therapy (TIMI22) PRAVASTATIN SODIUM - Actue Coronary Syndromes | Phase 4 | Completed | Bristol-Myers Squibb | 4000 | 2000-11-01 | 2011-04-15 |
| Bioavailability Study of Pravastatin Sodium 40 mg Tablets Under Fasting Conditions pravastatin sodium, Pravachol® - Healthy | Phase 1 | Completed | Teva Pharmaceuticals USA | 58 | 2000-09-01 | 2020-10-08 |
| A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood Pravastatin sodium, Simvastatin, Atorvastatin calcium - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 56 | 2021-10-29 | |
| Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids Pravastatin sodium, Fenofibrate - HIV Infections, Lipodystrophy | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 630 | 2021-11-01 | |
| The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs Pravastatin sodium, Simvastatin, Atorvastatin calcium - HIV Infections, HIV Seronegativity | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 56 | 2006-03-14 |
Congenital Abnormalities (3) · HIV Infections (3) · Leukemia, Myeloid, Acute (3) · Leukemia, Erythroblastic, Acute (2) · Leukemia, Megakaryoblastic, Acute (2) · Leukemia, Monocytic, Acute (2) · Leukemia, Myelomonocytic, Acute (2) · Lipodystrophy (2) · Pre-Eclampsia (2) · Anemia, Refractory, with Excess of Blasts (1) · Carcinoma, Hepatocellular (1) · Endometriosis (1) · Hyperlipidemias (1) · Inflammation (1) · Leukemia (1)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Dr. Reddy's Laboratories Limited (2) · Fred Hutchinson Cancer Center (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Bristol-Myers Squibb (1) · Dr. Robert F. Casper (1) · Federation Francophone de Cancerologie Digestive (1) · Massachusetts General Hospital (1) · SWOG Cancer Research Network (1) · Teva Pharmaceuticals USA (1) · The University of Texas Medical Branch, Galveston (1) · Universitas Airlangga (1) · University College, London (1)
United States (9) · Canada (2) · France (1) · Indonesia (1) · Puerto Rico (1) · United Kingdom (1)
Judith Aberg (2) · Ralph Scallion EE, MD (2) · Anjali Advani, MD (1) · Carl Fitchenbaum (1) · Dan Yeung, MD (1) · David A. Wohl, M.D. (1) · David C Henderson, M.D. (1) · Francesca Aweeka (1) · Jacques Denis, MD (1) · Jean-Louis Jouve (1) · John Gerber (1) · Maged Costantine, MD (1) · Mazyar Shadman (1) · Michael J. Seckl, MD, PhD (1) · Muhammad Ilham Aldika Akbar, MD, OBGYN (1)
PMID 16218799, PMID 16514303, PMID 17434848, PMID 18279736, PMID 18772061, PMID 19958964, PMID 20824151, PMID 21060068, PMID 21345849, PMID 21487089, PMID 21641362, PMID 23212806, PMID 27417011, PMID 29618479, PMID 32586346, PMID 36842489, PMID 41808442
P30CA015704 (1), U01AI068636 (1), U10CA032102 (1), U54HD047891 (1)