19 completed, 7 not yet recruiting, 6 unknown, 3 enrolling by invitation. 34 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 3, 1 Phase 4.
Follow Placebo Supplementation: new trials by email Literature Review of Placebo Supplementation trials Research Report on Placebo Supplementation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of Menopausal Status, Isoflavone Supplementation and Training on Cardiometabolic Function Women Red Clover Isoflavone Supplementation, Supervised exercise training, Placebo Supplementation - Menopause, Exercise Adaptation | Not applicable | Not yet recruiting | University of Copenhagen | 60 | 2027-10-15 | 2026-10-16 |
| Effects of Taurine Supplementation and Morning or Evening High-intensity Exercise on Circadian Clock Genes and Inflammatory Parameters in Adult Women With Obesity Taurine supplementation, Placebo Supplementation, High-intensity interval training (HIIT) - Obesity (Disorder), Inflammation | Not applicable | Not yet recruiting | University of Sao Paulo | 60 | 2027-01-01 | 2026-11-02 |
| Study on the Mechanism of Central Obesity Induced by Sleep Restriction and the Therapeutic Effect of n-3 Polyunsaturated Fatty Acid: a Randomized, Double-blind, Placebo-controlled Trial (COSPA Study) n-3 PUFA Supplementation, Placebo Supplementation, Experimental Sleep Restriction - Sleep Deprivation | Not applicable | Not yet recruiting | Beijing Anzhen Hospital | 40 | 2026-12-01 | 2026-10-27 |
| Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer. PROBIOTIC SUPPLEMENTATION BY OXXYSLAB®, PLACEBO supplementation - Colon Adenocarcinoma, Neuropathic Pain | Not applicable | Not yet recruiting | Centre Francois Baclesse | 130 | 2026-10-01 | 2026-07-30 |
| S-Acetyl Glutathione and Performance Recovery in Soccer 200 mg S-Acetyl Glutathione, 500 mg S-Acetyl Glutathione, Placebo Supplementation - Performance Recovery, Exercise-induced Inflammation | Not applicable | Not yet recruiting | University of Thessaly | 20 | 2026-09-01 | 2026-07-08 |
| The Effects of a Multicomponent Sleep & Recovery Supplement on Muscle Fatigue and Sleep magnesium-based sleep & recovery supplement, Placebo Supplementation - Athletes, Healthy | Not applicable | Not yet recruiting | University of Exeter | 25 | 2026-08-01 | 2026-08-10 |
| Probiotics and Biomarkers in Irritable Bowel Syndrome Probiotic Supplementation (Lactobacillus Reuteri), Placebo Supplementation - Irritable Bowel Syndrome (IBS) | Not applicable | Recruiting | Sahlgrenska University Hospital | 252 | 2026-04-28 | 2026-06-01 |
| The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms Pyridoxal-5'-Phosphate supplement, Placebo Supplementation - Neural Inhibition, Anxiety | Not applicable | Completed | University of Reading | 44 | 2026-03-23 | 2026-10-07 |
| The Impact of Omega-3 Fatty Acid Supplementation on the Composition of Erythrocyte Membranes EPA/DHA supplements, ALA supplements, Placebo supplements - Healthy Volunteers | Not applicable | Enrolling by invitation | The Jerzy Kukuczka Academy of Physical Education in Katowice | 200 | 2025-04-15 | 2026-06-08 |
| Effect of Oral Supplements for Influenza Vaccine Response ARA (Arachidonic Acid) Supplementation, TUDCA (Tauroursodeoxycholic Acid) Supplementation, Placebo Supplementation - Influenza Vaccine Response | Not applicable | Not yet recruiting | Tsinghua University | 45 | 2025-02-01 | 2025-02-14 |
| Effect of Endurance Training-Induced Coenzyme Q10 (CoQ10) Supplementation on Myokine, Exerkine Secretion and Cognitive Functions in Long-Distance Runners CoQ10 supplementation, Placebo supplementation - Health Knowledge, Attitudes, Practice | Phase 4 | Unknown | Gdansk University of Physical Education and Sport | 24 | 2024-08-23 | 2025-08-26 |
| Postbiotics Supplementation, Gut Microbiota Composition, and Exercise-induced Inflammation Postbiotics supplementation, Placebo supplementation - Postbiotics Supplementation | Not applicable | Completed | University of Thessaly | 15 | 2024-06-01 | 2026-02-04 |
| The Effect of Postbiotics Supplementation on Exercise-induced Oxidative Stress. Postbiotics supplementation, Placebo supplementation - Postbiotics Supplement | Not applicable | Completed | University of Thessaly | 16 | 2024-05-15 | 2024-12-04 |
| The Influence of Chlorella Supplementation on Running Performance Chlorella supplementation, Placebo supplementation - Athletes, Healthy | Not applicable | Unknown | University College, London | 20 | 2024-01-05 | 2024-06-28 |
| The Impact of Vitamin D Supplementation on Pregnant Women With the Risk of GDM Placebo supplementation, Vitamin D supplementation - Gestational Diabetes Mellitus | Not applicable | Unknown | IIMC, Riphah International University, Pakistan | 350 | 2024-01-01 | 2023-11-29 |
| Acute Microbial Switch Two day supplementation of a complex fiber mixture, Placebo supplementation - Insulin Sensitivity, Glucose Metabolism Disorders (Including Diabetes Mellitus) | Not applicable | Completed | Maastricht University Medical Center | 29 | 2023-11-24 | 2026-06-11 |
| Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation (SPOT) L-tyrosine supplementation, Placebo supplementation - Stress | Not applicable | Recruiting | Centre Hospitalier Universitaire de Nice | 150 | 2023-11-14 | 2025-12-08 |
| Targeting the Gut Dysbiosis to Treat Inflammation-driven Synaptopathy in MS Prebiotics and Probiotics supplementation, Placebo supplementation, peripheral blood withdrawal - Patient Participation | Not applicable | Unknown | Neuromed IRCCS | 100 | 2023-07-26 | 2023-08-14 |
| Sideritis Supplementation, Oxidative Stress and Health Sideritis Scardica (SidTea+) extract supplementation, Placebo supplementation - Oxidative Stress, Lipidemia | Not applicable | Completed | University of Thessaly | 30 | 2023-02-15 | 2023-12-14 |
| Physiological and Appetitive Effects of CBD Supplementation Cannabidiol (CBD) supplementation, Placebo supplementation - Appetitive Behavior, Adverse Effect | Not applicable | Unknown | Loughborough University | 30 | 2023-01-20 | 2023-03-17 |
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Obesity (3) · Overweight (3) · Dysbiosis (2) · Inflammation (2) · Acquired Immunodeficiency Syndrome (1) · Alopecia (1) · Anxiety Disorders (1) · Appetitive Behavior (1) · Behavior (1) · Colonic Neoplasms (1) · Dementia (1) · Depression (1) · Diabetes, Gestational (1) · Fatty Liver (1) · Genetic Diseases, Inborn (1)
University of Thessaly (4) · Maastricht University Medical Center (3) · University of Sao Paulo (3) · University College, London (2) · Applied Science & Performance Institute (1) · Bambino Gesù Hospital and Research Institute (1) · Beijing Anzhen Hospital (1) · CES University (1) · Centre Francois Baclesse (1) · Centre Hospitalier Universitaire de Nice (1) · Charite University, Berlin, Germany (1) · Columbia University (1) · Gdansk University of Physical Education and Sport (1) · Hospices Civils de Lyon (1) · IIMC, Riphah International University, Pakistan (1)
Greece (4) · United Kingdom (4) · United States (4) · Brazil (3) · Netherlands (3) · France (2) · Italy (2) · Poland (2) · Spain (2) · China (1) · Colombia (1) · Denmark (1) · Germany (1) · Mexico (1) · Monaco (1)
Chariklia K Deli, PhD (2) · Tom Gurney (2) · Annemie Schols, Prof. (1) · Athanasios Z. Jamurtas, Professor (1) · Carlo Dionisi-Vici, MD (1) · Chien-Wen Hou, Ph.D. (1) · Cristian D Hernandez, PhD Student (1) · Daniela Ricci, MD,PhD (1) · David T Field (1) · Diego Martinelli, MD, PhD (1) · Dimitrios Draganidis, PhD (1) · Giancarlo Iarossi, MD (1)
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