20 completed, 8 recruiting, 7 active not recruiting, 4 terminated. 43 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 43 | Completed 20, Recruiting 8, Active not recruiting 7, Terminated 4, Unknown 2, Withdrawn 2 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia Allogeneic Hematopoietic Stem Cell Transplantation, Anti-CD19-CAR CMV-specific T-lymphocytes, Biospecimen Collection - Acute Lymphoblastic Leukemia | Early Phase 1 | Recruiting | City of Hope Medical Center | 15 | 2025-12-30 | 2026-04-27 |
| Comparing a New PSMA Imaging Agent to MRI for Detecting Prostate Cancer, BEACON Trial Biopsy of Prostate, Biospecimen Collection, Computed Tomography - Prostate Carcinoma | Early Phase 1 | Recruiting | Jonsson Comprehensive Cancer Center | 30 | 2025-11-14 | 2026-03-10 |
| An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine Cancer Computed Tomography, Gallium Ga 68-DOTA-FAPI-04, Positron Emission Tomography - Neuroendocrine Tumor | Early Phase 1 | Recruiting | University of Michigan Rogel Cancer Center | 30 | 2025-09-16 | 2026-07-31 |
| Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease Biospecimen Collection, Dasatinib, Fisetin - Glioma | Early Phase 1 | Recruiting | Mayo Clinic | 30 | 2025-08-12 | 2026-10-01 |
| An Investigational Scan (rhPSMA-7.3 PET/CT) for Detecting Biochemically Recurrent Prostate Cancer, ENLIGHTEN Trial Computed Tomography, Electronic Health Record Review, Flotufolastat F-18 Gallium - Biochemically Recurrent Prostate Carcinoma, Prostate Adenocarcinoma | Early Phase 1 | Recruiting | Northwestern University | 27 | 2025-04-11 | 2026-07-02 |
| Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer Computed Tomography, Fludeoxyglucose F-18, Intensity-Modulated Proton Therapy - Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Early Phase 1 | Recruiting | Emory University | 20 | 2024-12-03 | 2025-10-22 |
| 64Cu-DOTA Pembrolizumab for Imaging Metastatic Solid Tumors in Patients Receiving Stereotactic Body Radiation Copper Cu 64-DOTA-pembrolizumab, Positron Emission Tomography, Stereotactic Body Radiation Therapy - Metastatic Malignant Solid Neoplasm | Early Phase 1 | Withdrawn | City of Hope Medical Center | 2023-08-25 | 2023-10-10 | |
| Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma Biospecimen Collection, Chimeric Antigen Receptor T-Cell Therapy, Computed Tomography - Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma | Early Phase 1 | Recruiting | City of Hope Medical Center | 9 | 2023-07-20 | 2026-02-04 |
| rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance Biopsy of Prostate, Decipher Prostate Cancer Test, Flotufolastat F-18 Gallium - Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8 | Early Phase 1 | Recruiting | Northwestern University | 40 | 2023-06-07 | 2026-07-02 |
| 18F-LY3950321-01 Biodistribution and Safety Study 18F-LY3950321, PET Scan - Diagnostic Agent Adverse Reaction, Radiation Exposure | Early Phase 1 | Completed | Avid Radiopharmaceuticals | 6 | 2023-02-28 | 2023-04-28 |
| BOLD MRI and FMISO PET for the Assessment of Hypoxic Tumor Microenvironment in Patients with Oligometastatic Liver Cancer Undergoing Yttirum-90 Selective Internal Radiation Therapy 18F-Fluoromisonidazole, Biopsy, Dynamic Contrast-Enhanced Magnetic Resonance Imaging - BCLC Stage a Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma | Early Phase 1 | Completed | Emory University | 9 | 2022-04-28 | 2025-03-13 |
| Early Clinical Evaluation of 18F-LY3546117 in Tumor Imaging 18F-LY3546117 Injection, PET Scan - Neoplasms, Neoplasms Malignant | Early Phase 1 | Unknown | Avid Radiopharmaceuticals | 30 | 2022-04-12 | 2022-04-25 |
| Imaging Study of 18F-FAC PET Scans to Assess Standard Treatment in People With Pancreatic Cancer PET Scan - Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma | Early Phase 1 | Active not recruiting | Memorial Sloan Kettering Cancer Center | 30 | 2021-11-18 | 2026-09-03 |
| FAPI PET for Lung Fibrosis 68Ga-FAPi-46, Computed Tomography, Positron Emission Tomography - Interstitial Lung Disease, Idiopathic Interstitial Pneumonias | Early Phase 1 | Active not recruiting | University of California, Los Angeles | 30 | 2021-11-16 | 2026-08-20 |
| 64 Cu-DOTA-alendronate PET Imaging in Localizing and Characterizing Breast Calcifications in Participants Before Undergoing Mastectomy Computed Tomography, Copper Cu-64-DOTA-alendronate, Pharmacokinetic Study - Breast Carcinoma, Calcification | Early Phase 1 | Completed | City of Hope Medical Center | 1 | 2021-11-03 | 2024-06-24 |
| Pharmacokinetics of IA and IV Ga68-PSMA-11 Infusion Angiogram, Catheterization, Gallium Ga-labeled PSMA-11 - Prostate Adenocarcinoma, Prostate Carcinoma | Early Phase 1 | Completed | Ryan Kohlbrenner, MD | 5 | 2021-10-13 | 2023-04-07 |
| CBD-Microglia PET Study [11C]PBR28, Low-dose lipopolysaccharide, Intradermal Capsaicin - CBD, Healthy | Early Phase 1 | Completed | Yale University | 28 | 2021-05-07 | 2026-04-29 |
| 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases Computed Tomography, 18F-FMAU, Multiparametric Magnetic Resonance Imaging - Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | Early Phase 1 | Completed | University of Southern California | 10 | 2021-02-15 | 2024-05-24 |
| Radiation Therapy, Plasma Exchange, and Immunotherapy (Pembrolizumab or Nivolumab) for the Treatment of Melanoma Nivolumab, Pembrolizumab, Radiation Therapy - Melanoma | Early Phase 1 | Completed | Mayo Clinic | 18 | 2020-12-14 | 2025-07-10 |
| 68Ga-FAPi-46 PET/CT Scan in Imaging Patients With Sarcoma Computed Tomography, Gallium Ga 68 FAPi-46, Positron Emission Tomography - Metastatic Sarcoma, Recurrent Sarcoma | Early Phase 1 | Active not recruiting | Jonsson Comprehensive Cancer Center | 18 | 2020-09-08 | 2026-09-17 |
Showing 20 of 43. Sign in to see all of them.
Prostatic Neoplasms (6) · Glioma (4) · Breast Neoplasms (3) · Colonic Neoplasms (3) · Melanoma (3) · Pancreatic Neoplasms (3) · Sarcoma (3) · Brain Neoplasms (2) · Carcinoma, Hepatocellular (2) · Carcinoma, Renal Cell (2) · Glioblastoma (2) · Lung Neoplasms (2) · Lymphoma, Large B-Cell, Diffuse (2) · Neoplasm Metastasis (2) · Neuroendocrine Tumors (2)
Mayo Clinic (9) · City of Hope Medical Center (5) · Jonsson Comprehensive Cancer Center (5) · M.D. Anderson Cancer Center (5) · Avid Radiopharmaceuticals (2) · Emory University (2) · Northwestern University (2) · Memorial Sloan Kettering Cancer Center (1) · National Cancer Institute (NCI) (1) · OHSU Knight Cancer Institute (1) · Rahul Aggarwal (1) · Ryan Kohlbrenner, MD (1) · Samus Therapeutics, Inc. (1) · Stanford University (1) · University of California, Los Angeles (1)
United States (40) · Australia (1)
Jeremie Calais, MD (3) · Nadia N. Laack, M.D. (3) · Ashley E Ross (2) · Ajit H. Goenka, M.D. (1) · Amol M Takalkar, MD, MS, MBA, FACNM (1) · Andrei Iagaru (1) · Arthur Y Hung, MD (1) · Ashish Patel, MD (1) · Benjamin Viglianti (1) · Bijoy Kundu, PhD (1) · Debra H. Brinkmann, Ph.D. (1) · Heiko Schoder, MD (1) · Homer A Macapinlac, MD (1) · Hossein Jadvar, MD (1)
PMID 34344873, PMID 34435552, PMID 34729628, PMID 35551087, PMID 36512649, PMID 39136560, PMID 39254446, PMID 39362770, PMID 40177325, PMID 41101974, PMID 41698328, PMID 41833067, PMID 42040934
P30CA033572 (4), P30CA016672 (3), P30CA060553 (2), P30CA138292 (2), N01CM37120 (1), P01CA042045 (1), P30CA006516 (1), P30CA014089 (1), P30CA068485 (1), P30CA069533 (1), P30CA124435 (1), P50CA108961 (1), R01CA178200 (1), R21CA259236 (1)