5 recruiting, 3 not yet recruiting, 2 unknown. 10 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Recruiting 5, Not yet recruiting 3, Unknown 2 |
| Phase 2 | 2 | Recruiting 1, Unknown 1 |
Follow PD-1 inhibitor: new trials by email Literature Review of PD-1 inhibitor trials Research Report on PD-1 inhibitor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Multicenter, Randomized, Controlled Phase III Clinical Trial on Adjuvant Intensified Therapy for Patients With Residual Disease After Neoadjuvant Treatment for Triple-negative Breast Cancer Capecitabine and PD-1 inhibitor, PD-1 inhibitor, Capecitabine - Newly Diagnosed Triple-negative Breast Cancer | Phase 3 | Not yet recruiting | Shandong Cancer Hospital and Institute | 852 | 2026-10-17 | 2026-10-09 |
| Chemotherapy Combined With or Without Short-Course Radiotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for High-Risk Locally Advanced Colon Cancer With pMMR/MSS short-course radiotherapy, Serplulimab, CapOx(Capecitabine+ Oxaliplatin) - Locally Advanced Colon Cancer, pMMR | Phase 3 | Not yet recruiting | Fudan University | 480 | 2026-10-15 | 2026-10-16 |
| RAIRI Model-Guided Adjuvant Therapy in Nasopharyngeal Carcinoma PD-1 inhibitor, Capecitabine - Nasopharyngeal Carcinoma (NPC) | Phase 3 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 651 | 2026-05-01 | 2026-06-04 |
| SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer short-course radiaotherapy, long-course chemoradiaothearpy, Capecitabine - Locally Advanced Rectal Cancer (LARC), MSS (Microsatellite Stable) | Phase 3 | Not yet recruiting | Fudan University | 612 | 2026-05-01 | 2026-04-24 |
| Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma Utidelone Capsule, Fluoropyrimidine- and Platinum-containing Therapy, Oxaliplatin - Gastric or Gastroesophageal Junction Adenocarcinoma | Phase 2 / Phase 3 | Recruiting | Beijing Biostar Pharmaceuticals Co., Ltd. | 778 | 2025-08-28 | 2025-11-25 |
| CCRT Followed by PD-1 Inhibitor Maintenance Therapy in Locally Advanced ESCC PD-1 inhibitor, Unlimited radiotherapy, TP regimen - Esophageal Carcinoma, Radiotherapy | Phase 3 | Recruiting | Fudan University | 452 | 2025-02-01 | 2026-04-17 |
| PD-1 Inhibitor Plus Chemotherapy With or Without Radiotherapy in Patients With Metastatic Esophageal Cancer Radiation, TP or PF regimen depended on investigator's choice., PD-1 inhibitor - Esophageal Neoplasms | Phase 3 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 436 | 2024-02-04 | 2024-07-16 |
| Chemoradiotherapy Combined With or Without PD-1 Blockade in Anal Canal Squamous Carcinoma Patients PD-1 inhibitor, concurrent chemoradiotherapy - Anal Canal Cancer Stage III, Anal Squamous Cell Carcinoma | Phase 3 | Unknown | Sixth Affiliated Hospital, Sun Yat-sen University | 102 | 2022-05-07 | 2022-05-16 |
| Sequential PD-1/PD-L1 Inhibitor and LENvatinib in TLCT and Refractory Hepatoblastoma After Chemotherapy PD-1 inhibitor - Transitional Cell Tumor, Hepatoblastoma | Phase 2 / Phase 3 | Unknown | RenJi Hospital | 15 | 2022-04-10 | 2022-04-11 |
| Study of Adjuvant Chemotherapy With or Without PD-1 Inhibitors and Chemoradiotherapy in Resected pN3 Gastric (G) or GEJ Adenocarcinoma PD-1 inhibitor, Oxaliplatin, Capecitabine - Gastric Cancer | Phase 3 | Recruiting | Fudan University | 433 | 2021-07-21 | 2021-08-10 |
Esophageal Neoplasms (2) · Anal Canal Carcinoma (1) · Anus Neoplasms (1) · Colonic Neoplasms (1) · Hepatoblastoma (1) · Liver Neoplasms (1) · Nasopharyngeal Carcinoma (1) · Neoplasms (1) · Spinocerebellar Degenerations (1) · Stomach Neoplasms (1)
Fudan University (4) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (2) · Beijing Biostar Pharmaceuticals Co., Ltd. (1) · RenJi Hospital (1) · Shandong Cancer Hospital and Institute (1) · Sixth Affiliated Hospital, Sun Yat-sen University (1)
China (9) · United States (1)
Hao Feng (1) · Junlin Yi, MD (1) · Lin Shen, MD (1) · Qiang Xia (1) · Sanjun Cai, MD (1) · Wen-Yang Liu, MD (1) · Xiang-bo Wan, PhD (1) · Zhen Zhang, MD (1) · Zhen Zhang, MD,PhD (1)
PMID 20354531, PMID 20956625, PMID 23578724, PMID 24035327, PMID 28453692, PMID 31534737, PMID 39545610, PMID 4830803, PMID 8874455