9 completed, 4 recruiting, 1 active not recruiting, 1 terminated. 6 Phase 2, 5 Not applicable, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Recruiting 3, Active not recruiting 1, Completed 1, Terminated 1 |
| Not applicable | 5 | Completed 5 |
| Phase 1 | 4 | Completed 2, Recruiting 2 |
| Phase 3 | 1 | Recruiting 1 |
Follow Palliative Radiation Therapy: new trials by email Literature Review of Palliative Radiation Therapy trials Research Report on Palliative Radiation Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Immunotherapy - Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | Phase 2 | Active not recruiting | Mayo Clinic | 3 | 2024-11-14 | 2026-10-15 |
| Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction Biospecimen Collection, Computed Tomography, Endobronchial Ultrasound Bronchoscopy - Malignant Solid Neoplasm | Phase 1 / Phase 2 | Recruiting | Roswell Park Cancer Institute | 42 | 2024-10-01 | 2026-04-06 |
| Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care stereotactic ablative radiation therapy, palliative radiation therapy, Chemotherapy - Oligometastatic Disease | Phase 2 / Phase 3 | Recruiting | National Medical Research Radiological Centre of the Ministry of Health of Russia | 100 | 2024-05-31 | 2024-08-16 |
| Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer Lurbinectedin, Palliative Radiation Therapy - Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8 | Phase 1 | Recruiting | Emory University | 22 | 2022-07-27 | 2025-10-31 |
| Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer Palliative Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration - Metastatic Malignant Neoplasm | Phase 2 | Recruiting | Roswell Park Cancer Institute | 1500 | 2019-11-18 | 2026-04-30 |
| Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma Laboratory Biomarker Analysis, Palliative Radiation Therapy, Pembrolizumab - Pleural Malignant Mesothelioma | Phase 1 | Completed | M.D. Anderson Cancer Center | 25 | 2017-05-01 | 2026-05-27 |
| Immunotherapy And Palliative Radiotherapy Combined In Patients With Advanced Malignancy Palliative Radiation Therapy - Palliative, Advanced Cancer | Completed | University Health Network, Toronto | 42 | 2017-01-10 | 2026-03-04 | |
| Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis External Beam Radiation Therapy, Palliative Radiation Therapy, Quality-of-Life Assessment - Malignant Neoplasm, Metastatic Malignant Neoplasm in the Bone | Not applicable | Completed | Wake Forest University Health Sciences | 102 | 2016-05-01 | 2026-08-21 |
| Study of Palliative Radiotherapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases Best Supportive Care, Palliative Radiation Therapy - Hepatocellular Carcinoma, Liver Metastases | Not applicable | Completed | Canadian Cancer Trials Group | 66 | 2015-12-11 | 2024-10-23 |
| NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy Autologous NY-ESO-1-specific CD8-positive T Lymphocytes, Laboratory Biomarker Analysis, Palliative Radiation Therapy - Sarcoma | Phase 1 | Completed | Fred Hutchinson Cancer Center | 2 | 2015-01-01 | 2017-07-05 |
| Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme Palliative Radiation Therapy, Questionnaire Administration, Radiation Therapy Treatment Planning and Simulation - Glioblastoma, Recurrent Brain Neoplasm | Not applicable | Completed | Jonsson Comprehensive Cancer Center | 10 | 2014-11-12 | 2019-02-28 |
| Palliative Radiotherapy Protocol in Head and Neck Cancer palliative radiation therapy - Head and Neck Neoplasms, Quality of Life | Phase 2 | Completed | Maisonneuve-Rosemont Hospital | 32 | 2011-06-01 | 2015-06-02 |
| Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer palliative surgery, therapeutic conventional surgery, palliative radiation therapy - Breast Cancer, Stage IV Breast Cancer | Not applicable | Completed | Eastern Cooperative Oncology Group | 390 | 2011-05-16 | 2023-06-29 |
| Aprepitant and Granisetron for the Prophylaxis of Radiation Induced Nausea and Vomiting - A Pilot Study Aprepitant, Palliative radiation therapy, Granisetron - Nausea, Vomiting | Phase 2 | Terminated | Sunnybrook Health Sciences Centre | 19 | 2011-01-01 | 2019-10-09 |
| Palliative 3-Dimensional Conformal Radiation Therapy in Reducing Radiation Side Effects in Patients With Lung Cancer. ICORG 06-34 questionnaire administration, quality-of-life assessment, 3-dimensional conformal radiation therapy - Lung Cancer | Not applicable | Completed | Cancer Trials Ireland | 40 | 2010-06-01 | 2016-03-31 |
Lung Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Glioblastoma (1) · Head and Neck Neoplasms (1) · Mesothelioma, Malignant (1) · Nausea (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Pain (1) · Sarcoma (1) · Small Cell Lung Carcinoma (1) · Vomiting (1)
Roswell Park Cancer Institute (2) · Canadian Cancer Trials Group (1) · Cancer Trials Ireland (1) · Eastern Cooperative Oncology Group (1) · Emory University (1) · Fred Hutchinson Cancer Center (1) · Jonsson Comprehensive Cancer Center (1) · M.D. Anderson Cancer Center (1) · Maisonneuve-Rosemont Hospital (1) · Mayo Clinic (1) · National Medical Research Radiological Centre of the Ministry of Health of Russia (1) · Sunnybrook Health Sciences Centre (1) · University Health Network, Toronto (1) · Wake Forest University Health Sciences (1)
United States (9) · Canada (5) · Ireland (1) · Israel (1) · Russia (1) · Saudi Arabia (1) · South Africa (1)
Anurag K Singh (1) · Bernard Fortin, MD MSc (1) · Dawn Owen, MD, PhD (1) · Doris R Brown (1) · Edward Chow, MBBS PhD FRCPC (1) · John Gerard Armstrong, MD, MB, MRCPI (1) · Konstantin Gordon (1) · Kristin Higgins, MD (1) · Laura Ann Dawson (1) · Matthew Ning, MD, MPH (1) · Nathaniel Ivanick (1) · Seema A. Khan, MD (1) · Seth Pollack (1) · Tania Kaprealian (1)
PMID 27020111, PMID 29548561, PMID 34995128, PMID 39245060
K23CA175167 (1), P30CA012197 (1), P30CA015704 (1), P30CA016042 (1), P30CA138292 (1), R01CA283547 (1), U10CA180794 (1)