11 completed, 2 terminated, 2 unknown, 2 withdrawn. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Completed 11, Terminated 2, Unknown 2, Withdrawn 2, Recruiting 1 |
Follow Paliperidone: new trials by email Literature Review of Paliperidone trials Research Report on Paliperidone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis Aripiprazole, Paliperidone - Schizophrenia, Treatment-resistant Schizophrenia | Phase 4 | Unknown | Consorcio Centro de Investigación Biomédica en Red (CIBER) | 244 | 2023-11-01 | 2023-09-29 |
| "Extended" (Alternate Day) Antipsychotic Dosing Risperidone, Olanzapine, paliperidone - Schizophrenia and Related Disorders, Drug Administration Schedule | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 120 | 2022-06-06 | 2026-04-13 |
| European Long-acting Antipsychotics in Schizophrenia Trial Aripiprazole, Aripiprazole depot, Paliperidone - Schizophrenia | Phase 4 | Completed | UMC Utrecht | 536 | 2015-02-01 | 2020-09-01 |
| Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients Olanzapine, Amisulpride, Risperidone - Schizophrenia, Schizophrenia and Disorders With Psychotic Features | Phase 4 | Completed | Technical University of Munich | 21 | 2015-02-01 | 2018-10-11 |
| A Comparison of Paliperidone and Risperidone for Treatment of Patirnts With Methamphetamine-Associated Psychosis paliperidone, Risperidone - Methamphetamine Dependence | Phase 4 | Completed | Wei Hao | 120 | 2013-02-01 | 2015-02-04 |
| A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia Paliperidone extended-release, Risperidone immediate-release - Schizophrenia | Phase 4 | Terminated | Johnson & Johnson Taiwan Ltd | 17 | 2013-01-01 | 2016-04-13 |
| Paliperidone ER(Invega®) on Depressive Symptoms of Schizophrenia Patients paliperidone - Schizophrenia | Phase 4 | Completed | Seoul National University Hospital | 11 | 2011-08-01 | 2019-04-09 |
| Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital paliperidone palmitate, risperidone, olanzapine - Schizophrenia | Phase 4 | Withdrawn | Ortho-McNeil Janssen Scientific Affairs, LLC | 2010-08-01 | 2013-07-08 | |
| 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated paliperidone, risperidone, haloperidole - Schizophrenia | Phase 4 | Completed | Janssen Scientific Affairs, LLC | 450 | 2010-05-01 | 2015-04-24 |
| Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation paliperidone, lithium, Placebo - Major Depressive Disorder, Suicidal Ideation | Phase 4 | Completed | University of Alabama at Birmingham | 54 | 2010-05-01 | 2016-03-03 |
| Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning Risperidone, Paliperidone - Schizophrenia | Phase 4 | Unknown | University of California, Irvine | 96 | 2009-07-01 | 2010-10-28 |
| Effects of Paliperidone in Posttraumatic Stress Disorder (PTSD) Paliperidone - Posttraumatic Stress Disorder | Phase 4 | Withdrawn | Yale University | 2008-09-01 | 2016-08-23 | |
| Paliperidone Extended Release(ER) Effectiveness Study to Evaluate the Objective Symptom Change and Symptomatic Remission Paliperidone - Schizophrenia | Phase 4 | Completed | Janssen Korea, Ltd., Korea | 190 | 2008-04-01 | 2014-06-03 |
| Phase 4 Study to Evaluate Efficacy of Paliperidone Extended-Release(ER) in Schizophrenic Participants Paliperidone - Schizophrenia | Phase 4 | Completed | Janssen Korea, Ltd., Korea | 387 | 2008-04-01 | 2014-09-10 |
| Efficacy Study of Paliperidone to Evaluate Subjective Change in Well-being and Drug Attitude in Schizophrenic Participants Paliperidone - Schizophrenia | Phase 4 | Completed | Janssen Korea, Ltd., Korea | 289 | 2008-04-01 | 2014-03-27 |
| PaliperidoNe Extended-Release [ER] Dosing and Clinical Response in Acute Schizophrenia Paliperidone - Schizophrenia | Phase 4 | Completed | Janssen Korea, Ltd., Korea | 491 | 2008-02-01 | 2014-03-05 |
| Invega (Paliperidone) for the Treatment of Mania in Children and Adolescents Ages 6-17 With Bipolar Disorder paliperidone - Pediatric Bipolar Disorder | Phase 4 | Terminated | Massachusetts General Hospital | 17 | 2007-11-01 | 2012-07-04 |
| Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy Risperidone microspheres, Risperidone, Olanzapine - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | Northwell Health | 357 | 2006-05-01 | 2018-07-10 |
Schizophrenia (14) · Psychotic Disorders (3) · Depression (2) · Bipolar Disorder (1) · Depressive Disorder, Major (1) · Diabetes Mellitus (1) · Lipid Metabolism Disorders (1) · Non-alcoholic Fatty Liver Disease (1) · Recurrence (1) · Schizophrenia Spectrum and Other Psychotic Disorders (1) · Schizophrenia, Treatment-Resistant (1) · Stress Disorders, Post-Traumatic (1) · Suicidal Ideation (1)
Janssen Korea, Ltd., Korea (4) · Centre for Addiction and Mental Health (1) · Consorcio Centro de Investigación Biomédica en Red (CIBER) (1) · Janssen Scientific Affairs, LLC (1) · Johnson & Johnson Taiwan Ltd (1) · Massachusetts General Hospital (1) · Northwell Health (1) · Ortho-McNeil Janssen Scientific Affairs, LLC (1) · Seoul National University Hospital (1) · Technical University of Munich (1) · UMC Utrecht (1) · University of Alabama at Birmingham (1) · University of California, Irvine (1) · Wei Hao (1) · Yale University (1)
United States (6) · South Korea (5) · Germany (2) · Austria (1) · Belgium (1) · Bulgaria (1) · Canada (1) · China (1) · Czechia (1) · Denmark (1) · Greece (1) · Hungary (1) · Israel (1) · Italy (1) · Netherlands (1)
Alexander Neumeister, MD (1) · Gary J Remington, MD, PhD (1) · Janet Wozniak, MD (1) · Javier Labad Arias, MD, PhD (1) · Markus Dold, MD (1) · Michael Davidson, professor (1) · Nina R. Schooler, PhD (1) · Rene S Kahn, professor (1) · Richard C Shelton, M.D. (1) · Stefan Leucht, Professor (1) · Steven G Potkin, M.D. (1)
PMID 22516251, PMID 24870446, PMID 25375367, PMID 25938474, PMID 26403322, PMID 26742509, PMID 32296355, PMID 33988924, PMID 36716759, PMID 37756123, PMID 38958149, PMID 40932600
U01MH070007 (1), U01MH070008 (1), U01MH070009 (1), U01MH070010 (1), U01MH070011 (1), U01MH070012 (1), U01MH070016 (1), U01MH070017 (1), U01MH070023 (1)