6 completed, 3 recruiting, 1 not yet recruiting. 10 Phase 2, 3 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Recruiting 3, Not yet recruiting 1 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 2 | Recruiting 2 |
Follow Normal Saline (Placebo): new trials by email Literature Review of Normal Saline (Placebo) trials Research Report on Normal Saline (Placebo)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Ipratropium Bromide on EILO Ipratropium Bromide, Normal Saline (Placebo) - Exercise-Induced Laryngeal Obstruction, Dyspnea During Activity | Phase 2 | Not yet recruiting | Cook Children's Health Care System | 50 | 2026-06-01 | 2026-05-05 |
| Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis. OnabotulinumtoxinA, Normal saline (placebo) - Base-of-thumb Osteoarthritis, Osteoarthritis | Phase 2 / Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 120 | 2025-12-03 | 2026-04-03 |
| IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study Ferric carboxymaltose IV, Normal Saline (Placebo) - Scoliosis Correction, Iron Deficiency | Phase 2 / Phase 3 | Recruiting | Columbia University | 120 | 2025-11-21 | 2025-11-26 |
| A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee Cryopreserved Devitalized Adipose Tissue Allograft, Normal Saline (Placebo) - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Britecyte | 46 | 2025-05-05 | 2026-09-08 |
| A Study to Assess the Safety, Reactogenicity, and Immunogenicity of SK Japanese Encephalitis Messenger Ribonucleic Acid (mRNA) Vaccines (GBP560) in Healthy Adults GBP560-A, GBP560-B, IXIARO - Japanese Encephalitis Virus Disease | Phase 1 / Phase 2 | Completed | SK Bioscience Co., Ltd. | 161 | 2025-02-24 | 2026-09-11 |
| Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients Dexmedetomidine Group / Group D, Normal Saline (Placebo) - Elective Surgical Patient, Hypertensive Patients | Phase 1 / Phase 2 | Recruiting | Liaquat National Hospital & Medical College | 60 | 2024-06-22 | 2024-12-11 |
| Role of Intravenous Dexmedetomidine in Reducing Shivering After Shivering Cesarean Section Due to Spinal Anesthesia Dexmedetomidine, Normal Saline (Placebo) - Shivering | Phase 2 | Completed | Liaquat National Hospital & Medical College | 60 | 2023-12-21 | 2024-12-02 |
| Mesenchymal Stem Cell Therapy in Diabetic Kidney Disease-A Double-blind, Placebo-controlled, Randomized Clinical Trial Mesenchymal stem cells, Normal Saline (Placebo) - Diabetic Kidney Disease | Phase 2 | Completed | National Institute of Blood and Marrow Transplant (NIBMT), Pakistan | 78 | 2022-12-01 | 2025-06-26 |
| A Study Evaluating Safety And Immunogenicity Of Meningococcal B Rlp2086 Vaccine In Adolescents meningococcal B rLP2086 vaccine., normal saline (placebo) - Meningitis, Meningococcal | Phase 2 | Completed | Pfizer | 538 | 2009-02-01 | 2015-04-14 |
| Safety of Darbepoetin Alfa Treatment in Patients With Severe Traumatic Brain Injury Darbeopoetin, Normal Saline (Placebo) - Traumatic Brain Injury | Phase 2 | Completed | Royal Alexandra Hospital | 10 | 2006-11-01 | 2012-03-05 |
Brain Injuries, Traumatic (1) · Diabetic Nephropathies (1) · Encephalitis, Japanese (1) · Hypertension (1) · Iron Deficiencies (1) · Meningitis, Meningococcal (1) · Osteoarthritis (1) · Osteoarthritis, Knee (1) · Scoliosis (1)
Liaquat National Hospital & Medical College (2) · Assistance Publique - Hôpitaux de Paris (1) · Britecyte (1) · Columbia University (1) · Cook Children's Health Care System (1) · National Institute of Blood and Marrow Transplant (NIBMT), Pakistan (1) · Pfizer (1) · Royal Alexandra Hospital (1) · SK Bioscience Co., Ltd. (1)
Pakistan (3) · United States (3) · Australia (2) · Canada (1) · France (1) · New Zealand (1) · Poland (1) · Spain (1)
Alla Danilkovitch (1) · Demetrios J. Kutsogiannis, MD MHS FRCPC (1)
PMID 22569484, PMID 27745812, PMID 32681472, PMID 35164991
2008 (1)