5 completed, 2 recruiting, 1 active not recruiting. 8 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 8 | Completed 5, Recruiting 2, Active not recruiting 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
Follow Normal Saline (Placebo): new trials by email Literature Review of Normal Saline (Placebo) trials Research Report on Normal Saline (Placebo)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve Adults Normal Saline (Placebo), PfSPZ-LARC2 Vaccine, PfSPZ Challenge (7G8) - Malaria Falciparum | Phase 1 | Recruiting | Sanaria Inc. | 42 | 2026-03-12 | 2026-11-03 |
| Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic Surgeries Dexmedetomidine, Normal Saline (Placebo) - Aki After Ascending Aortic Surgeries | Phase 1 | Active not recruiting | Ain Shams University | 78 | 2025-11-01 | 2026-06-09 |
| A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee Cryopreserved Devitalized Adipose Tissue Allograft, Normal Saline (Placebo) - Osteoarthritis of Knee | Phase 1 / Phase 2 | Completed | Britecyte | 46 | 2025-05-05 | 2026-09-08 |
| Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso PfSPZ-LARC2 Vaccine, Normal Saline (Placebo) - Malaria Falciparum, Malaria Infection | Phase 1 | Completed | Sanaria Inc. | 75 | 2025-03-04 | 2026-04-16 |
| A Study to Assess the Safety, Reactogenicity, and Immunogenicity of SK Japanese Encephalitis Messenger Ribonucleic Acid (mRNA) Vaccines (GBP560) in Healthy Adults GBP560-A, GBP560-B, IXIARO - Japanese Encephalitis Virus Disease | Phase 1 / Phase 2 | Completed | SK Bioscience Co., Ltd. | 161 | 2025-02-24 | 2026-09-11 |
| Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients Dexmedetomidine Group / Group D, Normal Saline (Placebo) - Elective Surgical Patient, Hypertensive Patients | Phase 1 / Phase 2 | Recruiting | Liaquat National Hospital & Medical College | 60 | 2024-06-22 | 2024-12-11 |
| Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults PfSPZ Vaccine, Normal Saline (Placebo), PfSPZ Challenge - Malaria, Plasmodium Falciparum Malaria | Phase 1 | Completed | Sanaria Inc. | 67 | 2014-04-01 | 2016-04-27 |
| Study of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia Congenita TD101, Normal saline (placebo) - Pachyonychia Congenita | Phase 1 | Completed | Pachyonychia Congenita Project | 1 | 2008-01-01 | 2008-11-19 |
Malaria (3) · Malaria, Falciparum (3) · Encephalitis, Japanese (1) · Hypertension (1) · Osteoarthritis, Knee (1) · Pachyonychia Congenita (1)
Sanaria Inc. (3) · Ain Shams University (1) · Britecyte (1) · Liaquat National Hospital & Medical College (1) · Pachyonychia Congenita Project (1) · SK Bioscience Co., Ltd. (1)
United States (2) · Australia (1) · Burkina Faso (1) · Egypt (1) · Germany (1) · New Zealand (1) · Pakistan (1) · Tanzania (1)
Alla Danilkovitch (1) · Peter Kremsner, MD (1) · Salim Abdulla, MD, PhD (1) · Sancy A Leachman, MD, PhD (1)