6 completed, 2 unknown, 1 not yet recruiting, 1 recruiting. 10 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 6, Unknown 2, Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Nerve Growth Factor: new trials by email Literature Review of Nerve Growth Factor trials Research Report on Nerve Growth Factor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nerve Growth Factor Encapsulated With 2-methacryloyloxyethyl Phosphorylcholine Nanocapsules in the Treatment of Amyotrophic Lateral Sclerosis Nerve Growth Factor - Amyotrophic Lateral Sclerosis | Phase 2 / Phase 3 | Not yet recruiting | Beijing Tiantan Hospital | 60 | 2024-05-01 | 2024-04-30 |
| Phase I Study of sss40 Injection for Moderate-to-Severe Bone Metastatic Cancer Pain Injection of humanized nerve growth factor (NGF) antibody - Cancer Pain | Phase 1 / Phase 2 | Recruiting | Shenyang Sunshine Pharmaceutical Co., LTD. | 132 | 2024-03-27 | 2025-06-06 |
| Efficacy and Safety of Nerve Growth Factor or Edaravone on Alcohol-induced Brain Injury Nerve Growth Factor, Edaravone, Combination of vitamin B1, B6, C, E and mecobalamine - Alcohol-induced Brain Injury | Phase 2 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 150 | 2019-06-30 | 2020-10-27 |
| An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye NGF, Vehicle - Dry Eye | Phase 2 | Completed | Dompé Farmaceutici S.p.A | 150 | 2017-01-20 | 2019-02-08 |
| A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery rhNGF, Vehicle - Ocular Discomfort | Phase 2 | Completed | Dompé Farmaceutici S.p.A | 180 | 2017-01-12 | 2024-04-19 |
| Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy Cerebrolysin (Nerve growth factor) - Cerebral Palsy Children, Children With Traumatic Brain Injury | Phase 2 | Unknown | Ain Shams University | 100 | 2014-04-01 | 2014-04-16 |
| BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy BG00010, Placebo - Painful Lumbar Radiculopathy, Sciatica | Phase 2 | Completed | Biogen | 183 | 2013-06-01 | 2015-09-10 |
| Study of Cerebrolysin for Treatment of Infants With History of Neonatal Hypoxic Ischemic Encephalopathy Cerebrolysin® - Hypoxic-Ischemic Encephalopathy | Phase 2 | Completed | Sahar M.A. Hassanein, MD | 40 | 2011-03-01 | 2013-09-13 |
| Effects of Intranasal Nerve Growth Factor for Traumatic Brain Injury nerve growth factor, nomral saline - Traumatic Brain Injury | Phase 2 | Completed | Jinling Hospital, China | 106 | 2010-12-01 | 2017-11-01 |
| A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy Nerve Growth Factor, Recombinant Human - HIV Infections, Peripheral Nervous System Disease | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 270 | 2021-11-04 |
Hereditary Sensory and Autonomic Neuropathies (3) · AIDS-Related Complex (1) · Acquired Immunodeficiency Syndrome (1) · Amyotrophic Lateral Sclerosis (1) · Atrophy (1) · Brain Injuries, Traumatic (1) · Cancer Pain (1) · Cerebral Palsy (1) · Demyelinating Diseases (1) · Dry Eye Syndromes (1) · HIV Infections (1) · Hypoxia-Ischemia, Brain (1) · Language Development Disorders (1) · Peripheral Nervous System Diseases (1) · Radiculopathy (1)
Dompé Farmaceutici S.p.A (2) · Ain Shams University (1) · Beijing Tiantan Hospital (1) · Biogen (1) · Jinling Hospital, China (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Sahar M.A. Hassanein, MD (1) · Shenyang Sunshine Pharmaceutical Co., LTD. (1) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (1)
China (3) · United States (3) · Egypt (2) · Italy (1)
Giacomina Massaro Giordano, MD (1) · Leonardo Mastropasqua, MD (1) · McArthur J (1) · Sahar M.A. Hassanein, MD, PhD (1) · Sahar MA Hassanein, MD (1) · Schifitto G (1) · Shuxia Luo (1) · Simpson D (1) · Xinfeng Liu, MD (1)