7 completed, 3 terminated, 3 unknown, 1 active not recruiting. 6 Not applicable, 6 Phase 3, 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 4, Active not recruiting 1, Terminated 1 |
| Phase 3 | 6 | Completed 2, Terminated 2, Unknown 2 |
| Phase 2 | 3 | Unknown 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Microspheres: new trials by email Literature Review of Microspheres trials Research Report on Microspheres
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Yttrium [90Y] Microsphere Injection in Combination With Targeted Immunotherapy in the Treatment of HCC Yttrium [90Y] Microsphere Injection, Conventional transcatheter arterial chemoembolization, Camrelizumab - HCC | Phase 2 | Recruiting | GrandPharma (China) Co., Ltd. | 120 | 2025-08-22 | 2026-01-12 |
| Genicular Artery Embolization Vs Observation for Symptomatic Knee Osteoarthritis Embozene MicroSpheres - Knee Osteoarthritis, Degenerative Joint Disease of Knee | Not applicable | Active not recruiting | University of California, Los Angeles | 100 | 2023-08-01 | 2026-04-29 |
| Transarterial Embolization Alone Versus Drug-Eluting Beads Chemoembolization for Hepatocellular Carcinoma DEB-TACE, TAE - Carcinoma, Hepatocellular | Phase 3 | Unknown | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 154 | 2019-12-04 | 2021-03-19 |
| Genicular Artery Embolization for the Treatment of Knee Osteoarthritis Embozene MicroSpheres - Knee Osteoarthritis, Degenerative Joint Disease of Knee | Not applicable | Completed | Siddharth Padia, MD | 40 | 2019-02-10 | 2022-11-30 |
| Feasibility of Holmium-166 Micro Brachytherapy in Head and Neck Tumors Holmium-166 (poly L lactic acid) microspheres - Radioisotopes, Head and Neck Neoplasms | Not applicable | Terminated | UMC Utrecht | 1 | 2016-09-01 | 2018-09-07 |
| Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization Holmium-166-poly (L-lactic acid) microspheres - Colorectal Neoplasms, Neoplasm Metastasis | Phase 2 / Phase 3 | Unknown | UMC Utrecht | 25 | 2014-11-01 | 2016-11-09 |
| Efficacy of Prostatic Artery Embolization (PAE) in Patients With Severe Benign Prostatic Hyperplasia (BPH) Microspheres - Benign Prostatic Hyperplasia | Not applicable | Completed | University of North Carolina, Chapel Hill | 15 | 2014-07-01 | 2017-09-14 |
| Uterine Fibroid Embolization- Long Term Follow up and Technical Perspectives embolizations ,uterine fibroid, embolizations - Uterine Fibroids, Arterial Embolization | Not applicable | Completed | Odense University Hospital | 52 | 2013-11-01 | 2016-11-28 |
| Study Of Intrahepatic Arterial Injection of 90-Y Glass Microspheres for Cholangiocarcinoma TheraSphere® Yttrium-90 (Y-90) Microspheres - Cholangiocarcinoma | Not applicable | Completed | H. Lee Moffitt Cancer Center and Research Institute | 25 | 2011-01-01 | 2017-03-22 |
| A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects azithromycin (AZ) microsphere, test chloroquine (CQ) formulation, azithromycin (AZ) - Malaria Prophylaxis | Phase 1 | Completed | Pfizer | 40 | 2010-04-01 | 2010-08-25 |
| Definitive Therapy for Oligometastatic Solid Malignancies Complete Surgical Removal, Stereotactic Radiosurgery, Ablative external beam radiation dose - Stage IV or Recurrent Carcinoma or Sarcoma | Phase 2 | Unknown | Rocky Mountain Cancer Centers | 110 | 2005-12-01 | 2013-07-15 |
| Extension Study of Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy Octreotide acetate in microspheres - Diabetic Retinopathy | Phase 3 | Terminated | Novartis Pharmaceuticals | 260 | 2005-11-01 | 2012-04-10 |
| Extension Study of the Long-term Safety and Tolerability of Octreotide Acetate in Patients With Moderately Severe or Severe Non-proliferative Diabetic Retinopathy or Low Risk Proliferative Diabetic Retinopathy Octreotide acetate in microspheres - Diabetic Retinopathy | Phase 3 | Terminated | Novartis Pharmaceuticals | 105 | 2005-11-01 | 2012-05-01 |
| Octreotide Acetate in Microspheres in Patients With Diabetic Retinopathy Octreotide Acetate in Microspheres, Placebo - Diabetic Retinopathy | Phase 3 | Completed | Novartis | 312 | 2000-02-01 | 2011-11-17 |
| Octreotide Acetate in Microspheres in Patients With Diabetic Retinopathy Octreotide Acetate in Microspheres 20 mg, Octreotide Acetate in Microspheres, Placebo - Diabetic Retinopathy | Phase 3 | Completed | Novartis | 583 | 1999-11-01 | 2011-11-17 |
Diabetic Retinopathy (4) · Chronic Pain (2) · Neoplasm Metastasis (2) · Osteoarthritis, Knee (2) · Carcinoma, Hepatocellular (1) · Cholangiocarcinoma (1) · Colorectal Neoplasms (1) · Digestive System Neoplasms (1) · Head and Neck Neoplasms (1) · Hyperplasia (1) · Leiomyoma (1) · Liver Diseases (1) · Multiple Endocrine Neoplasia Type 1 (1) · Prostatic Hyperplasia (1) · Recurrence (1)
Novartis (2) · Novartis Pharmaceuticals (2) · UMC Utrecht (2) · GrandPharma (China) Co., Ltd. (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Odense University Hospital (1) · Pfizer (1) · Rocky Mountain Cancer Centers (1) · Siddharth Padia, MD (1) · University of California, Los Angeles (1) · University of North Carolina, Chapel Hill (1)
United States (8) · Netherlands (2) · China (1) · Denmark (1) · Italy (1)
Ari Isaacson, MD (1) · Dennise Carter, MD (1) · Marnix G Lam, MD, PhD (1) · Max A Viergever, Prof. dr. ir. (1) · Rita Golfieri, Professor (1) · Sarah Hoffe, M.D. (1) · Siddharth A Padia, MD (1) · Siddharth Padia, M.D. (1) · Stevo Duvnjak, MD (1) · Zhiping Yan, MD (1)