6 completed, 3 terminated, 3 unknown, 1 active not recruiting. 6 Phase 4, 4 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1.
Follow this drug Literature Review of Metronidazole Oral trials Research Report on Metronidazole Oral
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vaginal lIve Biotherapeutic RANdomized Trial LC106, LC115, Placebo - Bacterial Vaginosis | Early Phase 1 | Completed | Massachusetts General Hospital | 24 | 2024-02-01 | 2025-03-25 |
| Metronidazole as Preoperative Therapy in CRC / FusoMetro-001 Metronidazole Oral - Colorectal Cancer | Phase 2 | Recruiting | Oncology Institute of Southern Switzerland | 40 | 2023-09-11 | 2025-11-18 |
| The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery Vancomycin Oral, Metronidazole Oral, Ciprofloxacin Pill - Systemic Inflammatory Response Syndrome, Postoperative Shock | Not applicable | Unknown | Radboud University Medical Center | 80 | 2022-03-01 | 2021-03-12 |
| Bowel Preparation in Elective Pediatric Colorectal Surgery Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral - Colostomy, Hirschsprung Disease - Pull Through | Not applicable | Unknown | McMaster University | 81 | 2022-01-01 | 2021-12-09 |
| Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial Vaginosis Dequalinium Chloride, Metronidazole Oral - Bacterial Vaginosis, Vaginal Infection | Phase 4 | Terminated | Medinova AG | 151 | 2021-07-26 | 2024-10-16 |
| Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis. Antibiotic - Complicated Appendicitis | Not applicable | Completed | Zealand University Hospital | 3193 | 2021-04-01 | 2024-10-01 |
| Flagyl Microbiome in Crohn's Disease Metronidazole Oral - Crohn Disease | Phase 4 | Completed | University of Louisville | 4 | 2021-03-21 | 2023-10-23 |
| Anti-protozoal Effect of Steroid Hormone 20-hydroxyecdysone 20-hydroxyecdysone Oral, Metronidazole Oral, Placebo Oral - Giardia Lamblia Infection | Phase 2 / Phase 3 | Active not recruiting | Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan | 200 | 2021-01-01 | 2025-04-04 |
| The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery Metronidazole Oral, Placebo - Endometriosis, Endometriosis-related Pain | Phase 4 | Terminated | University of Louisville | 78 | 2020-10-19 | 2026-06-18 |
| Parasitic Infection in Anemic Pregnant Women Iron Supplement, Metronidazole Oral, Albendazole - Anemia of Pregnancy | Phase 4 | Unknown | Cairo University | 200 | 2020-05-13 | 2021-02-09 |
| Treatment of Bacterial Vaginosis Prior to Active Labor and Infectious Morbidity Metronidazole Oral, Placebo Oral Tablet - Bacterial Vaginoses | Phase 1 | Terminated | The University of Texas Medical Branch, Galveston | 75 | 2019-10-11 | 2023-12-12 |
| Topical Versus Oral Metronidazole Following Excisional Haemorrhoidectomy Metronidazole Oral, Metronidazole Ointment, Placebo Oral Tablet - Hemorrhoids, Postoperative Pain | Phase 4 | Completed | University of Auckland, New Zealand | 120 | 2019-03-11 | 2020-11-03 |
| Antibiotic and Probiotic Therapies in the Adjuvant Treatment of the Chronic Periodontitis. Placebo Oral Tablet, Amoxicillin 500 Mg, Lactobacillus reuteri Oral Drops - Chronic Periodontitis Complex | Not applicable | Completed | Universidade Estadual Paulista Júlio de Mesquita Filho | 45 | 2018-05-02 | 2020-11-17 |
| Oral Metronidazole With Lactobacillus Vaginal Suppositories to Prevent Recurrence of Bacterial Vaginosis Metronidazole Oral, "Metronidazole" and "Lactobacillus" - Bacterial Vaginosis, Recurrence | Phase 4 | Completed | Peking University Shenzhen Hospital | 66 | 2017-07-01 | 2021-02-01 |
Vaginosis, Bacterial (4) · Vaginitis (2) · Chronic Periodontitis (1) · Colorectal Neoplasms (1) · Coronary Artery Disease (1) · Crohn Disease (1) · Endometriosis (1) · Enterocolitis, Necrotizing (1) · Giardiasis (1) · Hemorrhoids (1) · Inflammatory Bowel Diseases (1) · Intestinal Obstruction (1) · Meconium Ileus (1) · Pain, Postoperative (1) · Recurrence (1)
University of Louisville (2) · Cairo University (1) · Massachusetts General Hospital (1) · McMaster University (1) · Medinova AG (1) · Oncology Institute of Southern Switzerland (1) · Peking University Shenzhen Hospital (1) · Radboud University Medical Center (1) · Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan (1) · The University of Texas Medical Branch, Galveston (1) · Universidade Estadual Paulista Júlio de Mesquita Filho (1) · University of Auckland, New Zealand (1) · Zealand University Hospital (1)
United States (4) · Brazil (1) · China (1) · Czechia (1) · Denmark (1) · Egypt (1) · Netherlands (1) · New Zealand (1) · Poland (1) · Slovakia (1) · South Africa (1) · Switzerland (1) · Uzbekistan (1)
Abdurakhim Toychiev, PhD (1) · Andrew G Hill, MBChB (1) · Caroline Mitchell, MD, MPH (1) · Lisa VanHouwelingen, MD, MPH, FRCSC (1) · Maria Jardini, PhD (1) · Peter Pickkers, MD, PhD (1) · Philipp Grob, PhD (1) · Resad Pasic, MD, PhD (1) · Salvatore Giovanni Vitale, M.D. (1) · Sandra Kavalukas, MD (1) · Sangeeta Jain, MD (1) · Shangrong Fan, M.D. (1)
PMID 38696172, PMID 38796500, PMID 39019388, PMID 39379540, PMID 41050878, PMID 41382078
2019 (1)