16 completed, 11 terminated, 2 unknown, 1 active not recruiting. 31 Phase 2, 4 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 31 | Completed 16, Terminated 11, Unknown 2, Active not recruiting 1, Withdrawn 1 |
| Phase 1 | 4 | Terminated 3, Completed 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Ketoconazole: new trials by email Literature Review of Ketoconazole trials Research Report on Ketoconazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cytochrome P450 Inhibition to Decrease Dosage of Dasatinib for Chronic Myelogenous Leukemia Dasatinib Pill, Ketoconazole Pill - Chronic Myeloid Leukemia, Chronic Phase | Phase 2 | Unknown | Hospital Universitario Dr. Jose E. Gonzalez | 15 | 2024-11-01 | 2022-12-06 |
| ITT-5 Mechanisms of Spermatogenesis in Man Testosterone 1% Gel, Acyline, Dutasteride - Gonadotropin Deficiency | Phase 2 | Withdrawn | University of Washington | 2019-06-01 | 2019-12-18 | |
| Omiganan Twice a Day (BID) in Patients With Facial Seborrheic Dermatitis Omiganan, Ketoconazole, Placebo - Seborrheic Dermatitis | Phase 2 | Unknown | Maruho Co., Ltd. | 36 | 2018-10-22 | 2019-05-01 |
| Oral Calcitriol With Ketoconazole in CRPC Calcitriol, Ketoconazole, Hydrocortisone - Castration-resistant Prostate Cancer | Phase 2 | Terminated | Donald Trump, MD | 1 | 2017-01-06 | 2021-02-08 |
| Hormone Therapy Plus Chemotherapy as Initial Treatment for Local Failures or Advanced Prostate Cancer Doxorubicin, Ketoconazole, Docetaxel - Prostatic Neoplasms | Phase 2 | Terminated | The University of Texas Health Science Center, Houston | 19 | 2015-11-01 | 2018-11-28 |
| Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate Cancer Degarelix, Doxorubicin, Ketoconazole - Prostate Cancer | Phase 2 | Terminated | The University of Texas Health Science Center, Houston | 4 | 2015-10-01 | 2018-11-27 |
| Clinical Trial Comparing BL123 Versus Ketoconazole in Patients With Tinea Pedis Dapaconazole, Ketoconazole - Tinea Pedis | Phase 2 | Completed | Gilberto De Nucci | 60 | 2014-07-01 | 2016-07-07 |
| Ketoconazole as Inhibitor of the Enzyme CYP17 in Locally Advanced or Disseminated Granulosa Cell Tumour of Ovary Ketoconazole - Granulosa Cell Tumour of the Ovary | Phase 2 | Terminated | Grupo Español de Tumores Huérfanos e Infrecuentes | 6 | 2012-10-01 | 2015-01-21 |
| Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer Fenretinide/LXS + Ketoconazole - Ovarian Cancer, Cancer of Ovary | Phase 1 / Phase 2 | Terminated | South Plains Oncology Consortium | 12 | 2012-02-01 | 2020-08-27 |
| A Study to Assess the Potential Effects of Ketoconazole on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies Trabectedin, Ketoconazole, Dexamethasone or equivalent steroid - Neoplasm Metastases | Phase 1 / Phase 2 | Completed | Janssen Research & Development, LLC | 12 | 2011-02-01 | 2015-10-14 |
| Ketoconazole and Dexamethasone in Prostate Cancer Ketoconazole, Hydrocortisone, Dexamethasone - Prostate Cancer | Phase 2 | Completed | University of California, San Francisco | 32 | 2009-12-11 | 2020-06-29 |
| Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate Cancer ketoconazole, hydrocortisone, dutasteride - Prostate Cancer | Phase 1 / Phase 2 | Terminated | Dana-Farber Cancer Institute | 11 | 2009-09-29 | 2018-09-04 |
| 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer 177Lu-J591, Ketoconazole, Hydrocortisone - Prostate Cancer | Phase 2 | Active not recruiting | Weill Medical College of Cornell University | 55 | 2009-06-01 | 2026-11-05 |
| Use of Low Dose Ketoconazole in Prostate Cancer That Does Not Respond to Hormone Therapy and Prior Chemotherapy Ketoconazole, Hydrocortisone - Prostate Cancer | Phase 2 | Completed | University of California, Davis | 30 | 2009-05-01 | 2017-03-30 |
| A 4 Week Study of Elidel (Pimecrolimus) for the Treatment of Seborrheic Dermatitis Elidel, Ketoconazole Cream - Seborrheic Dermatitis | Phase 2 | Completed | Dermatology Specialists Research | 113 | 2007-05-07 | 2022-03-14 |
| Effect of Ketoconazole Inhibition of CYP3A on Urinary Excretion of Docetaxel Docetaxel, Ketoconazole - Solid Tumors | Phase 2 | Completed | National University Hospital, Singapore | 10 | 2006-10-01 | 2013-12-10 |
| Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating Patients With Prostate Cancer Calcitriol, Ketoconazole, Laboratory Biomarker Analysis - Prostate Adenocarcinoma, Recurrent Prostate Carcinoma | Phase 1 / Phase 2 | Terminated | Roswell Park Cancer Institute | 51 | 2006-10-01 | 2017-06-14 |
| Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery Essential amino acid supplement, Ketoconazole, Placebo - Hip Fracture, Osteoarthritis | Phase 2 | Completed | University of Arkansas | 40 | 2006-10-01 | 2014-06-02 |
| Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy ketoconazole, lenalidomide, therapeutic hydrocortisone - Prostate Cancer | Phase 2 | Completed | Case Comprehensive Cancer Center | 34 | 2006-09-01 | 2020-07-24 |
| Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer goserelin with dutasteride, goserelin with bicalutamide and dutasteride, goserelin with bicalutamide and dutasteride and ketoconazole - Cancer, Prostate Neoplasms | Phase 2 | Completed | University of Washington | 35 | 2006-07-01 | 2018-08-09 |
Showing 20 of 31. Sign in to see all of them.
Prostatic Neoplasms (16) · Neoplasms (3) · Dermatitis, Seborrheic (2) · Neoplasm Metastasis (2) · Breast Neoplasms (1) · Burns (1) · Femur Head Necrosis (1) · Genetic Diseases, Inborn (1) · Granulosa Cell Tumor (1) · Hip Fractures (1) · Hypogonadism (1) · Leukemia, Myeloid, Chronic-Phase (1) · Motor Activity (1) · Osteoarthritis (1) · Osteonecrosis (1)
Memorial Sloan Kettering Cancer Center (2) · National University Hospital, Singapore (2) · The University of Texas Health Science Center, Houston (2) · University of California, San Francisco (2) · University of Washington (2) · Beth Israel Deaconess Medical Center (1) · Case Comprehensive Cancer Center (1) · Dana-Farber Cancer Institute (1) · Dermatology Specialists Research (1) · Donald Trump, MD (1) · Gilberto De Nucci (1) · Grupo Español de Tumores Huérfanos e Infrecuentes (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · Janssen Research & Development, LLC (1)
United States (24) · Singapore (2) · Belgium (1) · Canada (1) · Mexico (1) · Netherlands (1) · Spain (1)
Robert J Amato, DO (2) · Arny Ferrando, PhD (1) · Barry J Maurer, MD, PhD (1) · Bernard Goffe, MD (1) · Boon Cher Goh, MBBS, MRCP (1) · Charles Ryan, MD (1) · David N Herndon, MD (1) · Debra Breneman, MD (1) · Gilberto De Nucci, PhD (1) · Glenn Bubley, MD (1) · Howard Scher, MD (1) · Jayanthi Lea, MD (1) · Jesus Garcia-Donas, MD (1) · Jorge Garcia, MD (1)
PMID 12610188, PMID 19734776, PMID 20430905, PMID 20881067, PMID 22463890, PMID 22606232, PMID 22895351, PMID 22932804, PMID 23150682, PMID 23303450, PMID 23533230, PMID 23851165, PMID 24009246, PMID 24298851, PMID 24323034, PMID 24655871, PMID 24824900, PMID 24918945, PMID 25100135, PMID 25211297, PMID 25514427, PMID 25667107, PMID 25807408, PMID 27171844, PMID 27433905, PMID 28240622, PMID 30191523, PMID 33270906, PMID 36708371
P30CA016056 (1), P30CA016672 (1), P50GM060338 (1), R01AR052293 (1)