9 completed. 7 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 7 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow JUUL: new trials by email Literature Review of JUUL trials Research Report on JUUL
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette Bupropion, Zonisamide, Placebo bupropion - Smoking Cessation | Phase 3 | Completed | Rose Research Center, LLC | 180 | 2021-12-14 | 2026-02-06 |
| Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures JUUL, Treatment As Usual - Smoking, Cigarette | Not applicable | Completed | Ohio State University Comprehensive Cancer Center | 350 | 2020-10-15 | 2023-07-21 |
| Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use Juul Electronic cigarette, Very Low Nicotine Cigarettes, Active Nicotine Patch - Nicotine Dependence | Phase 2 | Completed | University of Wisconsin, Madison | 209 | 2020-09-09 | 2023-05-25 |
| Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes JUUL, Tobacco - Nicotine Administration & Dosage, E-cigarettes | Not applicable | Completed | University of California, San Francisco | 17 | 2019-12-09 | 2025-10-16 |
| Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS - Electronic Cigarette Use, Cigarette Use, Electronic | Not applicable | Completed | Juul Labs, Inc. | 279 | 2019-09-17 | 2020-07-28 |
| Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes JUUL - Smoking Cessation, Harm Reduction | Not applicable | Completed | Rose Research Center, LLC | 50 | 2019-08-26 | 2025-04-20 |
| United States Pre-Market Tobacco Application Pharmacokinetics Virginia Tobacco flavored JUUL 5% ENDS, Cool Mint flavored JUUL 5% ENDS, Mango flavored JUUL 5% ENDS - Nicotine Dependence, Nicotine Dependence, Cigarettes | Not applicable | Completed | Juul Labs, Inc. | 67 | 2018-10-19 | 2021-06-14 |
| Study to Evaluate Constituents in Exhaled Breath and Room Air From Use of E-vapor Products and Conventional Cigarettes JUUL, VUSE Solo, Conventional Cigarette - Second Hand Tobacco Smoke | Not applicable | Completed | Juul Labs, Inc. | 43 | 2018-09-17 | 2021-06-14 |
| Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers Treatment with JUUL 5%, Virginia Tobacco, Treatment with JUUL 5%, Cool Mint, ENDS, Treatment with JUUL 5%, Mango, ENDS - Nicotine Dependence, Other Tobacco Product, Tobacco Use | Not applicable | Completed | Juul Labs, Inc. | 90 | 2018-03-04 | 2021-06-21 |
Vaping (7) · Tobacco Smoking (4) · Tobacco Use Disorder (4) · Tobacco Use (3) · Cigarette Smoking (2) · Harm Reduction (2) · Smoking Cessation (2) · Smoking (1) · Tobacco Use Cessation (1)
Juul Labs, Inc. (4) · Rose Research Center, LLC (2) · Ohio State University Comprehensive Cancer Center (1) · University of California, San Francisco (1) · University of Wisconsin, Madison (1)
United States (8) · Canada (1)
Mark Rubinstein, MD (1) · Megan E Piper, PhD (1) · Neal L Benowitz, MD (1) · Peter Couroux, MD (1) · Philip Mathew, M.D. (1) · Theodore L Wagener, PhD (1)
PMID 24814944, PMID 25607446, PMID 27401980, PMID 37230961, PMID 38348917, PMID 40803048
R01CA239309 (1), R01DA039264 (1), U01DA045537 (1)