13 completed, 3 unknown, 2 withdrawn, 1 terminated. 8 Phase 3, 7 Phase 4, 2 Phase 1, 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 6, Unknown 1, Withdrawn 1 |
| Phase 4 | 7 | Completed 4, Unknown 2, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
| Not applicable | 1 | Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
Follow IPV: new trials by email Literature Review of IPV trials Research Report on IPV
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study on the Immune Response and Safety of Inactivated Poliovirus Vaccine (IPV) When Co-administered With Human Rotavirus (HRV) Porcine Circovirus (PCV)-Free Vaccine in Healthy Chinese Infants HRV PCV-free, IPV - Gastroenteritis | Phase 3 | Completed | GlaxoSmithKline | 400 | 2024-03-22 | 2025-10-22 |
| Randomized Controlled Study on T-PEP Versus IPV Method for Lower Respiratory Airways Clearance in Tetraplegic Tracheotomized Spinal Cord Injured Patients T-PEP, IPV - Spinal Cord Injury Cervical | Not applicable | Withdrawn | Montecatone Rehabilitation Institute S.p.A. | 2022-02-01 | 2022-04-28 | |
| Immunogenicity and Safety of Concomitant and Non-Concomitant Administration of RotaTeq® (V260) and Inactivated Poliomyelitis Vaccine in Healthy Chinese Infants (V260-074) RotaTeq (V260), IPV - Prevention of Rotavirus Gastroenteritis in Infants and Children Caused by Serotypes G1, G2, G3, G4, and G9 | Phase 3 | Completed | Merck Sharp & Dohme LLC | 400 | 2020-08-25 | 2024-07-26 |
| Immunogenicity of Intramuscular and Intradermal IPV fIPV (0.1 mL) ID, fIPV (0.1mL) IM, fIPV (0.2mL) IM - Poliomyelitis | Phase 4 | Terminated | Centers for Disease Control and Prevention | 958 | 2019-10-06 | 2022-05-18 |
| Assessment of Poliovirus Type 2 Immunogenicity of One and Two Dose Schedule With IPV and fIPV When Administered at 9-13 Months of Age in Bangladesh IPV - Poliomyelitis | Phase 4 | Unknown | International Centre for Diarrhoeal Disease Research, Bangladesh | 300 | 2018-09-27 | 2022-04-13 |
| Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines PCV13, DTaP, HBV - Apnea, Apnea Neonatal | Phase 4 | Completed | Duke University | 223 | 2018-07-17 | 2024-02-14 |
| A Study to Evaluate Immunogenicity of Intramuscular Full-Dose and Intradermal Fractional Dose of IPV IPV, f-IPV - Poliomyelitis | Phase 3 | Completed | Fidec Corporation | 773 | 2017-10-23 | 2023-07-21 |
| A Study to Evaluate Immunogenicity of Various Schedules of Inactivated Polio Vaccine IPV, f-IPV - Poliomyelitis | Phase 3 | Withdrawn | Fidec Corporation | 2017-07-01 | 2017-06-27 | |
| Immunogenicity and Safety Profile of Primary Dose of bOPV Bio Farma Given Simultaneously With Pentabio And IPV bOPV, Pentabio, IPV - Healthy | Phase 4 | Completed | PT Bio Farma | 143 | 2016-07-01 | 2017-11-08 |
| Serological Survey on Monitoring the Positive Rate After Vaccination of Inactivated Polio Vaccine IPV, OPV - Poliomyelitis | Completed | Centers for Disease Control and Prevention, China | 809 | 2015-08-01 | 2017-08-01 | |
| Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules bOPV (three dose), bOPV (two dose), IPV - Poliomyelitis | Phase 4 | Completed | Centers for Disease Control and Prevention | 456 | 2015-04-01 | 2016-07-20 |
| Assessment of Community Transmission of Sabin Type 2 Virus in Bangladesh tOPV, bOPV, IPV - Vaccine Virus Shedding | Phase 3 | Unknown | University of Virginia | 810 | 2015-04-01 | 2016-10-26 |
| Polio End-game Strategies - Poliovirus Type 2 Challenge Study IPV, bOPV, bOPV and IPV - Poliomyelitis | Phase 4 | Completed | Aga Khan University | 900 | 2014-09-01 | 2016-05-03 |
| Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine IPV, bOPV, mOPV type 2 - Polio | Phase 4 | Unknown | University of Chile | 570 | 2013-04-01 | 2014-05-20 |
| Safety and Immunogenicity of a New Inactivated Poliovirus Vaccine in Infants IPV, Low dose Sabin-IPV, Low dose adjuvanted Sabin-IPV - Poliomyelitis | Phase 1 / Phase 2 | Completed | Pauline Verdijk | 140 | 2012-02-01 | 2014-02-21 |
| Immunogenicity and Safety Study of Booster Dose of GSK Biologicals' IPV (Poliorix™) and DTPa/Hib (Infanrix+Hib™) Vaccine Infanrix+Hib™, Poliorix™ - Acellular Pertussis, Tetanus | Phase 3 | Completed | GlaxoSmithKline | 831 | 2011-10-01 | 2018-06-06 |
| Safety and Immunogenicity of a New Inactivated Polio Vaccine in Healthy Adults IPV, Sabin-IPV, Adjuvanted Sabin-IPV - Poliomyelitis | Phase 1 | Completed | Pauline Verdijk | 45 | 2011-08-01 | 2014-02-21 |
| Pneumococcal Vaccine Booster Study in Healthy Children 12-18 Mths Old Previously Primed With the Same Vaccines Synflorix, Tritanrix-HepB, Hiberix - Infections, Streptococcal | Phase 3 | Completed | GlaxoSmithKline | 756 | 2007-10-22 | 2019-01-14 |
| Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' 10-valent Pneumococcal Conjugate Vaccine Pneumococcal conjugate vaccine GSK1024850A, Prevenar, Tritanrix-HepB - Infections, Streptococcal | Phase 3 | Completed | GlaxoSmithKline | 806 | 2006-08-07 | 2018-12-07 |
Poliomyelitis (10) · Pneumococcal Infections (2) · Streptococcal Infections (2) · Apnea (1) · Diphtheria (1) · Gastroenteritis (1) · HIV Seropositivity (1) · Haemophilus Infections (1) · Premature Birth (1) · Quadriplegia (1) · Tetanus (1)
GlaxoSmithKline (4) · Centers for Disease Control and Prevention (2) · Fidec Corporation (2) · Pauline Verdijk (2) · Aga Khan University (1) · Centers for Disease Control and Prevention, China (1) · Duke University (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Merck Sharp & Dohme LLC (1) · Montecatone Rehabilitation Institute S.p.A. (1) · PT Bio Farma (1) · University of Chile (1) · University of Virginia (1)
Bangladesh (4) · China (4) · Poland (4) · Philippines (2) · Chile (1) · Dominican Republic (1) · Indonesia (1) · Italy (1) · Pakistan (1) · Panama (1) · United States (1)
Pauline Verdijk, PhD (2) · Ali F Saleem, MBBS,FCPS,MSc (1) · Andrea Trembath, MD (1) · Carlotta Stopazzoni, MD (1) · Huaqing Wang, MD, PhD (1) · K Zaman, MBBS, PhD (1) · Karen Broder, MD (1) · Kusnandi Rusmil (1) · Mami Taniuchi, PhD (1) · Mary A Staat, MD (1) · Miguel L O'Ryan, MD (1) · Rachel G Greenberg, MD (1) · Stella Gutierrez, MD (1)
PMID 19325447, PMID 19325451, PMID 19325452, PMID 24063976, PMID 25043278, PMID 26318714, PMID 28693854, PMID 29477307, PMID 30376086, PMID 33284114, PMID 34932560, PMID 35575051, PMID 38509699, PMID 39146859, PMID 39761016