14 completed, 9 unknown, 3 recruiting, 2 terminated. 11 Phase 1, 7 Not applicable, 4 Phase 2, 3 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 5, Unknown 3, Terminated 2, Recruiting 1 |
| Not applicable | 7 | Unknown 5, Completed 2 |
| Phase 2 | 4 | Completed 4 |
| Phase 3 | 3 | Recruiting 2, Completed 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
Follow Injections, Intravenous: new trials by email Literature Review of Injections, Intravenous trials Research Report on Injections, Intravenous
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Safety and Efficacy of NouvSoma001 in Ischemic Stroke extracellular vesicles derived from human induced neural stem cell for intravenous injection, a placebo of extracellular vesicles derived from human induced neural stem cell for intravenous injection - Ischemic Stroke | Phase 1 | Recruiting | Wei Wang | 69 | 2025-11-30 | 2026-01-21 |
| Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery Midazolam, REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO] - Postoperative Cognitive Dysfunction, Orthopedic Procedures | Phase 3 | Recruiting | Romanian Society for Enteral and Parenteral Nutrition | 120 | 2025-10-01 | 2025-10-01 |
| Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord Injury Esketamine(Continuous infusion), Remifentanil (Target-Controlled Infusion), Flurbiprofen (Single intravenous injection) - Chronic Pain | Not applicable | Unknown | Beijing Tiantan Hospital | 60 | 2024-08-25 | 2024-08-13 |
| The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION, Placebo - Brain Tumor, Bleeding | Phase 3 | Recruiting | Stephen Lownie | 102 | 2024-04-03 | 2026-03-19 |
| Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis Aleeto, intravenous injection, intrathecal injection - Amyotrophic Lateral Sclerosis | Phase 1 | Unknown | Beijing Tiantan Hospital | 24 | 2023-12-15 | 2023-12-26 |
| Norwegian Randomized Trial on Indocyanine Green Cholangiography Utility for Laparoscopic Cholecystectomy, Prestudy Direct gallbladder injection of ICG intraoperatively, Intravenous injection 2.5 mg, Intravenous injection and direct gallbladder injection - Gall Stone, Cholecystitis | Not applicable | Unknown | Ostfold Hospital Trust | 100 | 2023-03-03 | 2023-03-29 |
| Analgesic Effect of Esketamine in DCSB in Adultscontrolled Study Esketamine 0.1mg/kg intravenous injection, Normal saline - Analgesia, Burns | Not applicable | Unknown | Shenzhen Second People's Hospital | 52 | 2022-12-01 | 2022-11-03 |
| Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION - Hypotension During Surgery, Blood Loss, Surgical | Phase 4 | Completed | University of Alabama at Birmingham | 115 | 2022-11-11 | 2026-05-27 |
| Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy Ibuprofen 800 Mg in 8 mL INTRAVENOUS INJECTION [Caldolor], Scalp nerve block - Supratentorial Brain Tumor | Phase 4 | Unknown | Ankara University | 102 | 2022-11-01 | 2023-03-10 |
| Comparison of Recovery From General Anesthesia in Remimazolam With Flumazenil vs. Propofol REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO], Flumazenil, Propofol - Recovery | Not applicable | Completed | Seoul National University Hospital | 66 | 2022-08-02 | 2023-01-13 |
| Effect of Remimazolam and Propofol on Hemodynamic Stability During Anesthesia Induction in OPCAB Patients REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO], Propofol, Rocuronium - Hemodynamic Instability | Not applicable | Completed | Seoul National University Hospital | 106 | 2022-07-26 | 2023-11-22 |
| Anti-malaria MAb in Malian Children L9LS (VRC-MALMAB0114-00-AB) Subcutaneous injection, L9LS (VRC-MALMAB0114-00-AB) intravenous injection, Placebo - Plasmodium Falciparum Infection, Malaria | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 365 | 2022-03-18 | 2025-07-10 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Recurrent/Metastatic Head and Neck Cancers Mitoxantrone Hydrochloride Liposome, intravenous injection (IV) - Recurrent Head and Neck Cancer, Metastatic Head and Neck Cancer | Phase 1 | Completed | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 45 | 2021-07-01 | 2024-03-07 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Gastric Carcinoma Mitoxantrone Hydrochloride Liposome, intravenous injection - Advanced Gastric Carcinoma | Phase 1 | Terminated | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 21 | 2021-03-30 | 2024-03-07 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Solid Tumor Mitoxantrone Hydrochloride Liposome, intravenous injection (IV) - Advanced Solid Tumor | Phase 1 | Unknown | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 90 | 2021-01-13 | 2021-11-01 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Relapsed Ovarian Cancer Mitoxantrone Hydrochloride Liposome, intravenous injection (IV) - Platinum-resistant Ovarian Cancer | Phase 1 | Terminated | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 56 | 2021-01-12 | 2024-03-07 |
| Ammonia N-13 Myocardial Blood Flow Absolute Quantification by PET in Patients With Known or Suspected CAD (Ammonia MAP) Myocardial Perfusion Imaging Study, AMMONIA N-13 37.5 mCi in 1 mL INTRAVENOUS INJECTION [Ammonia N 13] - Myocardial Ischemia, Coronary Disease | Completed | Ionetix Corporation | 170 | 2020-09-14 | 2024-09-05 | |
| To Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson's Disease Dementia Ceftriaxone, Placebo - Parkinson's Disease Dementia | Phase 2 | Completed | BrainX Corporation | 100 | 2019-02-15 | 2026-07-22 |
| Transcutaneous Electric Nerve Stimulation for Pain Relief During Extracorporeal Shock-wave Lithotripsy Transcutaneous electrical nerve stimulation, Fentanyl - Pain | Not applicable | Unknown | Ain Shams University | 60 | 2018-02-20 | 2018-04-10 |
| A Healthy Volunteer Pharmacokinetics (PK)/Pharmacodynamics (PD), Safety and Tolerability Study of Andexanet in Healthy Japanese and Caucasian Subjects Andexanet alfa, Apixaban, Rivaroxaban - Bleeding | Phase 2 | Completed | Portola Pharmaceuticals | 108 | 2017-08-28 | 2023-02-24 |
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Hemorrhage (2) · Agnosia (1) · Amyotrophic Lateral Sclerosis (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Blood Loss, Surgical (1) · Brain Neoplasms (1) · Burns (1) · Cardiovascular Diseases (1) · Cholecystitis (1) · Chronic Pain (1) · Cognitive Dysfunction (1) · Coronary Artery Disease (1) · Coronary Disease (1) · Gallstones (1)
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. (4) · Royan Institute (3) · Beijing Tiantan Hospital (2) · Seoul National University Hospital (2) · Acacia Pharma Ltd (1) · Ain Shams University (1) · Ankara University (1) · AstraZeneca (1) · BrainX Corporation (1) · Ionetix Corporation (1) · Maastricht University Medical Center (1) · Maxinase Life Sciences Ltd. (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · National Taiwan University Hospital (1) · Ostfold Hospital Trust (1)
China (7) · United States (5) · Iran (3) · Taiwan (3) · South Korea (2) · Canada (1) · Egypt (1) · Mali (1) · Netherlands (1) · Norway (1) · Romania (1) · Turkey (Türkiye) (1)
Hamid Gourabi, PhD (3) · Nasser Aghdami, MD,PhD (3) · Reza Moghadasali, PhD (2) · Soroosh Shekarchian, MD (2) · Yunseok Jeon, MD, PhD (2) · Ana Maria Dumitriu, MD, PhD (1) · Atieh Makhloogh, MD (1) · Brian Kinard, DMD, MD (1) · Chuan Qin, MD (1) · Daishi Tian, MD (1) · David Han, MD (1) · Doenja Lambregts, MD (1) · Geerard Beets, Ass Prof. MD (1) · Gholamreza Pourmand, MD (1)
PMID 1269083, PMID 1900224, PMID 20554319, PMID 21492816, PMID 21816311, PMID 22007073, PMID 24266542, PMID 25534062, PMID 25558198, PMID 27539843, PMID 2788669, PMID 28283245, PMID 31831982, PMID 34824110, PMID 34952528, PMID 35900437, PMID 37104115, PMID 37311758, PMID 38052364, PMID 38205822, PMID 38669354, PMID 39126872, PMID 40975121, PMID 8106689, PMID 8229231, PMID 8890809