High-Flow Nasal Cannula: Clinical Trials

31 trials of High-Flow Nasal Cannula, newest first

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15 completed, 6 not yet recruiting, 6 unknown, 2 recruiting. 27 Not applicable.

By phase and status

PhaseTrialsStatus
Not applicable27Completed 12, Not yet recruiting 6, Unknown 6, Recruiting 2, Terminated 1

Follow High-Flow Nasal Cannula: new trials by email Literature Review of High-Flow Nasal Cannula trials Research Report on High-Flow Nasal Cannula

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Effect of Different-Flow High-Flow Nasal Cannula Versus Traditional Face Mask Oxygenation on Safe Apnea Time in Obese Patients
Face Mask, High-Flow Nasal Cannula - Obesity
Not applicableNot yet recruitingThe First People's Hospital of Lianyungang1472026-10-012026-09-28
High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary Disease
High-flow nasal cannula - Hypoxemia, Gastric Cancer (Diagnosis)
Not applicableNot yet recruitingZhejiang University902026-08-292026-08-28
Comparison of High-Flow Nasal Cannula and Tight Face Mask for Maintaining Oxygenation During Rapid Sequence Induction
High-Flow Nasal Cannula, Tight Face Mask - Hypoxemia, Airway Management
Not applicableNot yet recruitingKhyber Teaching Hospital2902026-08-012026-07-23
Effect of High-Flow Nasal Cannula Oxygen Therapy on Hypoxemia in Pediatric Sedated Bronchoscopy
High-flow nasal cannula, Regular Nasal Cannula - Hypoxemia, Pneumonia
Not applicableNot yet recruitingZhejiang University4302026-04-012026-05-01
POM vs HFNC for Hypoxemia Prevention in Children
Procedural Oxygen Mask, High-Flow Nasal Cannula - Hypoxemia
Not applicableCompletedBedirhan Günel302026-03-042026-05-22
High-flow Nasal Cannula Versus Conventional Oxygen During Awake Tracheal Intubation With Difficult Airways
High-Flow Nasal Cannula, Ligh-Flow Nasal Cannula - Awake Tracheal Intubation, Difficult Airway
Not applicableRecruitingWenxian Li3362026-02-042026-07-28
High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients
High-flow nasal cannula - Hypoxemia, Esophageal Cancer
Not applicableCompletedZhejiang University802025-09-052025-11-25
LMA vs High-flow Nasal Oxygen During ECT in Obese Patients
Laryngeal Mask Airway, High-Flow Nasal Cannula - Electroconvulsive Therapy Treated Patients, Obesity
Not applicableNot yet recruitingEulji University Hospital252025-08-012025-07-30
Procedural Oxygen Mask vs. High-flow Nasal Cannula for Hypoxemia Prevention During ERCP
Procedural Oxygen Mask, High-Flow Nasal Cannula - Hypoxemia
Not applicableCompletedKocaeli City Hospital1502025-03-072025-06-04
Home High-Flow Nasal Cannula vs. Noninvasive Ventilation for Stable Chronic Respiratory Failure
High-Flow Nasal Cannula, Noninvasive Ventilation - Stable Chronic Hypercapnic Respiratory Failure
Not applicableUnknownWonju Severance Christian Hospital382025-03-012025-03-12
High Flow Nasal Cannula for Stabilization of Extremely Premature Infants
High-Flow Nasal Cannula - Premature Infant, Ventilation Therapy
Not applicableNot yet recruitingCharles University, Czech Republic602024-12-012024-11-14
Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial
high-flow nasal cannula - High-flow Nasal Cannula, Children
Not applicableRecruitingHenan Provincial People's Hospital482024-06-152025-12-01
Physiological Effects of High-flow Nasal Cannula During Exercise
High-flow Nasal Cannula - Healthy Volunteers
Not applicableCompletedPontificia Universidad Catolica de Chile142022-07-252023-12-07
Comparison of High Flow vs Standard Nasal Cannula in Children With Burns Under Sedoanalgesia
Conventional Nasal Cannula, High-flow nasal cannula, midazolam, ketamine, propofol - Burns
Not applicableCompletedZeliha Alicikus502022-03-102025-11-19
Physiological Effects of Non-invasive Mechanical Ventilation Versus High-flow Nasal Cannula in Critically Ill Patients at High Risk of Extubation Failure
Non-invasive ventilation (NIV), High-flow nasal cannula - Weaning From Mechanical Ventilation
Not applicableCompletedPontificia Universidad Catolica de Chile222021-09-162024-12-30
High Flow Nasal Cannula is Appropriate Alternative for Stabilization of Very Premature Infants: a Prospective Observational Study
High-Flow Nasal Cannula - Premature; Infant
Not applicableCompletedCharles University, Czech Republic652021-02-012024-11-12
High Flow Nasal Cannula With Noninvasive Ventilation
Standard of Care - Nasal Cannula, High-flow nasal cannula, HFNC plus non-invasive ventilation - Acute Respiratory Failure
Not applicableCompletedUniversity of Oklahoma62020-09-012023-11-21
Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation
High-flow nasal cannula, Low SpO2 - High-flow Nasal Cannula, Exercise Capacity
Not applicableUnknownNational Hospital Organization Minami Kyoto Hospital322020-07-182023-03-28
Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC
High-flow nasal cannula - High-flow Nasal Cannula, Exercise Capacity
Not applicableCompletedNational Hospital Organization Minami Kyoto Hospital502020-07-012022-09-30
Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures
High-flow nasal cannula, Surgical mask, bronchoscopy examination - Transmission, Patient Professional, High-flow Nasal Cannula
CompletedRush University Medical Center152020-05-202021-04-23

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Conditions studied

Hypoxia (11)  ·  Respiratory Insufficiency (4)  ·  Pulmonary Disease, Chronic Obstructive (3)  ·  Disease (2)  ·  Esophageal Neoplasms (2)  ·  Hypercapnia (2)  ·  Obesity (2)  ·  Pneumonia (2)  ·  Premature Birth (2)  ·  Stomach Neoplasms (2)  ·  Acidosis, Respiratory (1)  ·  Burns (1)  ·  Colonic Neoplasms (1)  ·  Dyspnea (1)  ·  Head and Neck Neoplasms (1)

Sponsors

Zhejiang University (3)  ·  Charles University, Czech Republic (2)  ·  National Hospital Organization Minami Kyoto Hospital (2)  ·  Pontificia Universidad Catolica de Chile (2)  ·  University of Oklahoma (2)  ·  Asan Medical Center (1)  ·  Bedirhan Günel (1)  ·  Eulji University Hospital (1)  ·  Henan Provincial People's Hospital (1)  ·  Hospital Clinic of Barcelona (1)  ·  Hôpital de Verdun (1)  ·  Karolinska University Hospital (1)  ·  Khyber Teaching Hospital (1)  ·  Kocaeli City Hospital (1)  ·  Nantes University Hospital (1)

Countries

China (7)  ·  United States (5)  ·  Turkey (Türkiye) (3)  ·  Chile (2)  ·  Czechia (2)  ·  Japan (2)  ·  South Korea (2)  ·  Canada (1)  ·  France (1)  ·  Italy (1)  ·  Spain (1)  ·  Taiwan (1)

Top investigators

Celia Y Quang, MD (1)  ·  Chun-Yu Wu, MD,PhD (1)  ·  Diansan Su (1)  ·  Ivan Pavlov, MD (1)  ·  Jie Li, PhD (1)  ·  Jun Zhou, PHD (1)  ·  Karen Allen, MD (1)  ·  Malin Jonsson Fagerlund (1)  ·  Nicholas S Hill, MD (1)  ·  Patricio Garcia, PhD(C) (1)  ·  Ricard Mellado Artigas, MD (1)  ·  Seong-Soo Choi, Dr. (1)  ·  Thomas J Caruso, M.D., M.Ed. (1)

Results publications

PMID 31577036, PMID 16354864, PMID 26060320, PMID 26926168, PMID 27706464, PMID 27997805, PMID 28860265, PMID 29208754, PMID 30326893, PMID 30996619, PMID 32195955, PMID 32890016, PMID 33144080, PMID 41735369