45 completed, 6 unknown, 3 terminated, 2 active not recruiting. 15 Phase 4, 13 Phase 2, 12 Not applicable, 12 Phase 3, 9 Phase 1.
Follow halofantrine: new trials by email Literature Review of halofantrine trials Research Report on halofantrine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RSV Vaccination to Reduce Recurrent AECOPD RSV vaccination (Arexvy, GlaxoSmithKline) - COPD, RSV | Phase 4 | Not yet recruiting | Chinese University of Hong Kong | 320 | 2027-07-01 | 2026-04-13 |
| Pandemic Influenza Vaccine in Organ Transplantation (PIVOT Trial) H5N1 vaccine (Arepanrix, GSK), Placebo - Influenza (Pandemic), Avian Influenza | Phase 3 | Active not recruiting | University Health Network, Toronto | 120 | 2025-11-03 | 2026-10-23 |
| A Study to Evaluate the Safety of Recombinant Herpes Zoster Vaccine for Healthy Individuals Recombinant herpes zoster vaccine with low-dose adjuvant, Recombinant herpes zoster vaccine with high-dose adjuvant, Low-dose adjuvant - Herpes Zoster (HZ) | Phase 1 / Phase 2 | Recruiting | Shanghai Institute Of Biological Products | 645 | 2025-04-04 | 2026-01-07 |
| Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia. Labetalol, Phentolamine - Severe Pre-eclampsia | Not applicable | Unknown | Assiut University | 200 | 2024-05-20 | 2024-04-26 |
| Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed People WELLBUTRIN SR (Bupropion HCI) Sustained-Release Tablets, 150 mg; GlaxoSmithKline, Cipralex (escitalopram) - Major Depressive Disorder (MDD) | Phase 4 | Recruiting | Medical University of Vienna | 120 | 2022-12-01 | 2024-11-05 |
| Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy Ondansetron 4mg + dexmedetomidine 0.5 ug/kg + normal saline ., Ondansetron 4mg + dexamethasone 8mg + normal saline. - Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy | Phase 2 | Unknown | Tanta University | 70 | 2022-09-15 | 2023-08-30 |
| Dental Biofilm Control During Orthodontic Treatment fixed metal orthodontic appliance, fixed non-metal orthodontic appliance, oral hygiene - Gingivitis, Malocclusion | Phase 3 | Active not recruiting | University of Rijeka | 80 | 2021-11-01 | 2026-01-30 |
| Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX) Herpes zoster vaccination (Shingrix, GSK), Influenza Vaccine (Fluarix Tetra Northern Hemisphere 2021 or 2022, GSK), Placebo - Influenza, Herpes Zoster | Phase 2 | Completed | Radboud University Medical Center | 148 | 2021-09-20 | 2023-06-29 |
| Evaluate the Ability of dOFM for BE Testing of Topically Applied Diclofenac Sodium Products in Healthy Subjects Voltaren - Diclofenac sodium gel 1% (GSK, USA), Pennsaid 2 % Topical Solution (Horizon Therapeutics, USA), Diclofenac sodium gel 1% (Perrigo, USA) - Healthy | Not applicable | Completed | Joanneum Research Forschungsgesellschaft mbH | 22 | 2020-10-08 | 2022-08-26 |
| Pain Management During Screening for Retinopathy of Prematurity Ibuprofen (Sanofi, Istanbul, Turkey), Paracetamol (GlaxoSmithKline, Istanbul, Turkey) - Retinopathy of Prematurity, Pain Management | Completed | Istanbul Medeniyet University | 44 | 2020-01-01 | 2021-02-23 | |
| Association of Two Desensitizing Protocols to Control Dentinal Hypersensitivity in Non-carious Lesions Photon Laser III-DMC (without radiation emission) + My First- Colgate, Photon Laser III-DMC (without radiation emission) + Sensodyne® Rapid Relief / GSK, Photon Laser III-DMC (with irradiation emission) + My First- Colgate - Dental Hypersensitivity | Not applicable | Completed | Universidade Federal do Para | 24 | 2019-08-07 | 2020-11-27 |
| Steroids and/ or Non-steroidal Anti-inflammatory Drugs in the Postoperative Regime After Trabeculectomy. Voltaren Ophtha 1 mg/ml, GSK, Monopex 1 mg/ml, Théa - Glaucoma | Phase 4 | Unknown | Copenhagen University Hospital, Rigshospitalet | 70 | 2019-08-01 | 2022-10-26 |
| Oral Health-related Quality of Life and Masticatory Function After Using Denture Adhesive and Denture Liner denture adhesive (Polident®, GlaxoSmithKline, Ireland) - Complete Denture, Complete Edentulism | Phase 3 | Completed | Chulalongkorn University | 80 | 2019-01-31 | 2021-06-28 |
| Comparison of Three Antibiotic Protocols in Prevention of Infection in Dental Implant Surgery Amoxicillin - Dental Implant Failed | Not applicable | Completed | Shiraz University of Medical Sciences | 450 | 2016-09-30 | 2020-11-20 |
| Validating Egg-based Diagnostics and Molecular Markers for the Spread of Anthelmintic Resistance Albendazole Pill 400mg (GSK) - Soil-transmitted Helminth Infections | Not applicable | Completed | University Ghent | 1000 | 2016-08-15 | 2019-10-21 |
| Hypertonic Saline Enhances The Field of View of Clinicians and Ease of Procedures Intranasal solutions application were done including one solution for per patient before nasoendoscopy procedure according to randomization - Nasopharyngeal Diseases | Phase 4 | Completed | Selcuk University | 200 | 2016-02-01 | 2020-01-02 |
| Cytogenetic Damage in Buccal Cells Caused by Toothpaste Toothpaste non-fluoride and fluoride - Toxicity | Not applicable | Completed | University of Split, School of Medicine | 40 | 2016-01-01 | 2017-10-30 |
| A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Children GlaxoSmithKline (GSK) Biologicals' investigational recombinant chimpanzee adenovirus Type 3-vectored Ebola Zaire vaccine (ChAd3-EBO-Z) (GSK3390107A), Nimenrix powder and solvent for solution for injection in pre-filled syringe; Meningococcal group A, C, W-135 and Y conjugate vaccine - Virus Diseases | Phase 2 | Completed | GlaxoSmithKline | 600 | 2015-11-09 | 2018-05-03 |
| Remifentanil Anesthesia and Postoperative BIS in Cardiac Surgery Remifentanil, sevoflurane and sufentanil - Cardiovascular Disease | Not applicable | Completed | Konkuk University Medical Center | 38 | 2015-10-01 | 2020-08-19 |
| A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Adults GlaxoSmithKline (GSK) Biologicals' investigational recombinant chimpanzee adenovirus Type 3-vectored Ebola Zaire vaccine (ChAd3-EBO-Z) (GSK3390107A), Placebo - Virus Diseases | Phase 2 | Completed | GlaxoSmithKline | 3024 | 2015-07-15 | 2018-01-04 |
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Depression (4) · Hepatitis B (4) · Carcinoma, Hepatocellular (3) · HIV Infections (3) · Influenza, Human (3) · Malaria (3) · Virus Diseases (3) · Herpes Zoster (2) · Leishmaniasis (2) · Liver Diseases (2) · Liver Neoplasms (2) · Malaria, Falciparum (2) · Nausea (2) · Neoplasms (2) · Papillomavirus Infections (2)
GlaxoSmithKline (10) · Sandoz (4) · U.S. Army Medical Research and Development Command (2) · University of Oxford (2) · Assiut University (1) · Azienda Ospedaliera di Padova (1) · Brigham and Women's Hospital (1) · Cancer Prevention and Research Institute, Italy (1) · Catholic University of the Sacred Heart (1) · Chinese University of Hong Kong (1) · Chulalongkorn University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Dr. Reddy's Laboratories Limited (1) · Eastern Hepatobiliary Surgery Hospital (1) · Hui Zhuang (1)
United States (7) · Canada (4) · China (4) · Brazil (3) · Burkina Faso (3) · Italy (3) · South Korea (3) · Tanzania (3) · Austria (2) · Germany (2) · Ghana (2) · Kenya (2) · Mali (2) · Netherlands (2) · Senegal (2)
Soran Hong, M.D. (2) · Andrew J Pollard, BA, MBBS, FRCPCH, PhD (1) · Ari Silbermintz (1) · Athina Siampalioth, MD (1) · Britta Hahn, Ph.D. (1) · Bruno Levecke, PhD (1) · Daniela Jensen, MD (1) · Daniella Bach-Holm, MD, Ph.D. (1) · Declan M McLoughlin, PhD (1) · Eric Bicrell, M.D. (1) · Felipe T Martinez, MD (1) · Fiona van der KLis, MD, PhD (1) · Francesca M Carozzi, PhD (1)
PMID 41276263, PMID 17265499, PMID 17284544, PMID 20113920, PMID 20456031, PMID 21384334, PMID 21419775, PMID 21422117, PMID 22216840, PMID 22228003, PMID 22761759, PMID 22848378, PMID 22859317, PMID 23571176, PMID 23723319, PMID 24237764, PMID 24285844, PMID 24565019, PMID 24576907, PMID 24731816, PMID 25153328, PMID 25418873, PMID 25910919, PMID 26176261, PMID 26407817, PMID 26702637, PMID 27216309, PMID 27266507, PMID 27329447, PMID 27482002, PMID 27728850, PMID 28093483, PMID 28306142, PMID 28470856, PMID 29179625, PMID 29668978, PMID 29756531, PMID 30388108, PMID 30715452, PMID 30975019, PMID 31369558, PMID 31369562, PMID 31532795, PMID 31626649, PMID 31708182, PMID 31948661, PMID 32199491, PMID 32199492, PMID 32532234, PMID 33188272
2009 (1), 2014 (1), 2019 (1), R01HL091157 (1), R21MH095824 (1)