24 completed, 7 unknown, 4 recruiting, 4 terminated. 26 Not applicable, 5 Phase 1, 5 Phase 2, 3 Early Phase 1, 1 Phase 3.
Follow GLP-1: new trials by email Literature Review of GLP-1 trials Research Report on GLP-1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of LEUVATE on Glycemia, Insulinemia, Aminoacidemia, and Protein Synthesis in GLP-1 RA-treated Adults GLP-1 - The Whole-body Protein Synthesis Response to Protein With Amino Acid or Amino Acids | Not applicable | Not yet recruiting | Nutraceutical Innovations LLC | 8 | 2026-06-01 | 2026-05-20 |
| Insulin-Mediated Glucose Uptake and Organ Perfusion Assessed by Total-Body PET During GIP and GLP-1 Infusion GIP, GLP-1, Saline (0.9% Sodium Chloride) - Type 2 Diabetes, Healhty | Not applicable | Recruiting | Copenhagen University Hospital, Rigshospitalet | 36 | 2026-03-12 | 2026-10-27 |
| People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists GLP-1, Ocrelizumab (US) - Multiple Sclerosis | Recruiting | Northwestern University | 100 | 2025-11-15 | 2026-03-17 | |
| Behavioral Therapy and GLP-1 Analogue Effects on Binge Eating, Weight, and Coping in Obesity GLP-1, CBTe Group Therapy - Binge Eating Disorder Associated With Obesity, Binge Eating Disorder | Recruiting | Haukeland University Hospital | 80 | 2025-07-01 | 2025-09-15 | |
| Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures GLP-1, Placebo - Longevity, Quality of Life | Early Phase 1 | Enrolling by invitation | AgelessRx | 150 | 2024-11-01 | 2025-07-30 |
| GLP-1 Medicines and Mental Health Changes GLP-1 - Obesity, Depression | Not applicable | Completed | University of California, San Diego | 90 | 2024-05-01 | 2026-01-27 |
| The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function GIP(1-42), GLP-1, GLP-2 - Incretin Effect | Not applicable | Completed | University of Copenhagen | 50 | 2023-01-04 | 2026-04-29 |
| Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes GLP-1, Insulin, Dextrose 20 % in Water - Type 1 Diabetes, Insulin Sensitivity/Resistance | Early Phase 1 | Withdrawn | University of Virginia | 2019-10-14 | 2022-03-22 | |
| Acute Effects of GLP-1 on Renal Hemodynamics Glucagon-Like Peptide 1, saline 0.9% - The GLP-1-mediated Gut-kidney Axis | Not applicable | Completed | Copenhagen University Hospital, Rigshospitalet | 10 | 2019-04-01 | 2020-04-07 |
| Influence of Dairy Protein Breakfast on Glycemia, Weight Loss and Clock Genes in T2D Continuous glucose monitoring CGM, Clock Genes m RNA expression, Postprandial Glucose - Type2 Diabetes, Healthy Obesity, Metabolically | Not applicable | Unknown | Tel Aviv University | 60 | 2018-12-28 | 2018-12-11 |
| Effect of GIP After a Meal in Patients With Type 2 Diabetes GIP(3-30)NH2, Peripheral venous cannulation, GLP-1 - Type2 Diabetes | Not applicable | Completed | University Hospital, Gentofte, Copenhagen | 10 | 2017-08-01 | 2021-04-27 |
| To Determine the Effect of GLP1 on Cognitive Function, Brain Glucose Metabolism and Neuroplasticity. RYGB, GLP-1 - Glucose Metabolism Disorders, Obesity | Not applicable | Completed | University of Pisa | 14 | 2016-06-29 | 2018-07-19 |
| Effects of GLP-1 on Chronic Heart Failure GLP-1, Placebo - Heart Failure | Not applicable | Unknown | Shi Yang | 68 | 2016-01-01 | 2016-01-08 |
| GLP-1 on Non-ST-Segment Elevation Myocardial Infarction GLP-1, Placebo - Myocardial Infarction | Not applicable | Unknown | Chinese PLA General Hospital | 90 | 2015-10-01 | 2015-10-19 |
| GLP-1 Loading During Elective Percutaneous Coronary Intervention GLP-1, placebo - Angina Pectoris, Myocardial Infarction | Phase 2 | Unknown | Papworth Hospital NHS Foundation Trust | 193 | 2015-03-01 | 2018-06-06 |
| Characterizing the Incretin Effect of Amino Acids and Defining GLP-1 Role on Skeletal Muscle GLP-1, Insulin Actrapid, Oral amino acids - Sarcopenia | Not applicable | Completed | University of Nottingham | 40 | 2014-11-01 | 2018-05-02 |
| Incretin Regulation of Insulin Secretion in Monogenic Diabetes GLP-1, Exendin 9-39 - Monogenic Diabetes | Phase 1 | Completed | University of Chicago | 10 | 2014-01-01 | 2017-04-10 |
| Umbilical Cord Mesenchymal Stem Cells and Liraglutide in Diabetes Mellitus GLP-1, SC, Standard Medical Treatment - Type 2 Diabetes | Phase 1 / Phase 2 | Unknown | Diabetes Care Center of Nanjing Military Command | 100 | 2013-10-01 | 2014-02-20 |
| GLP-1 and Hypoglycemia Glucagon-Like Peptide- 1 (GLP-1) infusion, Placebo Comparator: Saline Infusion - Type 2 Diabetes Mellitus | Early Phase 1 | Completed | University of Maryland, Baltimore | 28 | 2013-07-01 | 2026-11-06 |
| Beta-cell Response to Incretin Hormones in Cystic Fibrosis GLP-1, GIP - Cystic Fibrosis, Pancreatic Insufficiency | Not applicable | Recruiting | University of Pennsylvania | 45 | 2013-05-01 | 2026-01-14 |
Showing 20 of 43. Sign in to see all of them.
Diabetes Mellitus, Type 2 (9) · Obesity (8) · Hypoglycemia (5) · Diabetes Mellitus (4) · Diabetes Mellitus, Type 1 (3) · Insulin Resistance (3) · Heart Failure (2) · Inflammation (2) · Myocardial Infarction (2) · Overweight (2) · Agnosia (1) · Angina Pectoris (1) · Binge-Eating Disorder (1) · Body Weight (1) · Cognitive Dysfunction (1)
Copenhagen University Hospital, Rigshospitalet (4) · Johns Hopkins University (3) · University of Copenhagen (3) · Mikkel Christensen (2) · University Hospital, Gentofte, Copenhagen (2) · Uppsala University (2) · Aarhus University Hospital Skejby (1) · AgelessRx (1) · Chinese PLA General Hospital (1) · David Dalessio (1) · Diabetes Care Center of Nanjing Military Command (1) · Haukeland University Hospital (1) · Karolinska Institutet (1) · Katarina Kos (1) · Mayo Clinic (1)
United States (13) · Denmark (12) · China (3) · Sweden (3) · United Kingdom (3) · Austria (1) · Canada (1) · Finland (1) · Germany (1) · Israel (1) · Italy (1) · Norway (1)
Dariush Elahi, PhD (3) · Adrian Vella, MD (1) · Ali Asmar, MD, PhD (1) · Astrid Plamboeck, M.D. (1) · Birgitte Brock, MD (1) · David D'Alessio, MD (1) · David M. Thompson, MD (1) · Farrah J Mateen (1) · Iskandar Idris, DM, FRCP (1) · Jens Holst, DMSCi (1) · Katarina Kos, MD, PHD (1) · Michael R. Rickels, MD, MS (1) · Michelle R Adams, PhD (1)
PMID 18298441, PMID 19094067, PMID 20805279, PMID 23599045, PMID 24516103, PMID 24735885, PMID 24891019, PMID 25053587, PMID 25158865, PMID 25675385, PMID 26043228, PMID 26542491, PMID 26567860, PMID 26573925, PMID 27143183, PMID 28096259, PMID 29099978, PMID 29177486, PMID 31203378, PMID 31277053, PMID 34016263, PMID 35111398, PMID 35363252, PMID 35729365, PMID 35796669, PMID 36260533, PMID 36734354, PMID 36933790, PMID 41578008
2025 (1), R01DK102359 (1)