51 completed, 4 recruiting, 4 unknown, 2 active not recruiting. 52 Not applicable, 6 Phase 2, 3 Phase 1, 2 Phase 3.
Follow Fruit: new trials by email Literature Review of Fruit trials Research Report on Fruit
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rutazyme Lemon Fermented Product Capsules for Metabolic Function in Adults With Obesity Rutazyme® Lemon Fermented Product Capsule, Placebo Capsule (Maltodextrin; GLUCIDEX®12) - Obesity, Metabolic Syndrome | Not applicable | Recruiting | National Taiwan Sport University | 40 | 2026-03-16 | 2026-04-21 |
| Acute Effects on Stem Cell Surveillance Anthocyanin-rich berry extract, Anthocyanin-rich flower/leaf extract, Berry /leaf blend - Stem Cell Surveillance | Not applicable | Not yet recruiting | Natural Immune Systems Inc | 48 | 2026-01-01 | 2026-01-14 |
| Food Insecurity and MASLD: A Fruit and Vegetable Intervention Study Fruit/vegetable vouchers - MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Food Insecurity Among Children | Not applicable | Recruiting | University of California, San Francisco | 48 | 2025-07-30 | 2025-09-02 |
| Vouchers for Improving Transplant Access to Lifestyle Nutrition - Kidney Transplant Fruit and Vegetable Voucher Support Program - Food Insecurity, Kidney Transplant | Not applicable | Completed | University of California, San Francisco | 19 | 2025-05-30 | 2026-03-11 |
| The Precision Nutrition New York Study Whole Grain Intervention then fruits and vegetables, Fruit and Vegetable Intervention and then whole grains - Body Composition Changes, Body Weight Changes | Not applicable | Recruiting | Cornell University | 15 | 2025-01-13 | 2025-07-11 |
| Effects of the Combined Intervention of Exercise, Fruit, and Vitamin Supplementation on Frailty in Older Adults the combined intervention of exercise, fruit, and vitamin supplementation - Frailty | Not applicable | Active not recruiting | Nanjing Medical University | 934 | 2024-03-08 | 2025-12-19 |
| Diet Intervention Pilot: Refining a Meal and Food Delivery Approach Increased EPA, DHA, fruit, and vegetable intake - Healthy Individuals | Not applicable | Completed | University of British Columbia | 10 | 2024-01-29 | 2024-11-27 |
| Effect of Flavored on!® Nicotine Pouch Products on Smoking Behaviors: a SMART Study Access to all varieties of on! 4mg nicotine pouches (Berry, Citrus, Cinnamon, Wintergreen, Mint, Coffee, and Original), Access to Original on! 4mg nicotine pouches, Non-Flavored then complete flavor on! nicotine pouches - Cigarette Smoking Behavior | Not applicable | Unknown | Altria Client Services LLC | 400 | 2023-09-11 | 2024-07-11 |
| Increased Access to Fruits and Vegetables for Hypertension in Immigrant Hispanic/Latinx Individuals Fruit and vegetable supplement, Dietary and chronic disease management education - Cardiovascular Diseases | Not applicable | Completed | St. Catherine University | 21 | 2023-03-28 | 2024-03-28 |
| Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes Nicotine 0 mg/mL, Nicotine 6 mg/mL, Nicotine 12 mg/mL - Nicotine, E-liquid Flavors | Phase 2 | Completed | Yale University | 54 | 2022-10-27 | 2024-08-05 |
| Facial Skin Clinical and Microbial Profiling From Oral Probiotic Supplementation Probiotic with niacin and berry extract, Probiotic without niacin and berry extract, Placebo - Healthy, Skin Manifestations | Not applicable | Completed | Oriflame Cosmetics AB | 109 | 2022-09-26 | 2023-05-01 |
| Effect of a Fruit- and Chaya-Based Diet on Genomic Instability and Biochemical Markers in Women With Breast Cancer Receiving Chemotherapy Fruits and chaya infusion, Conventional diet - Breast Cancer | Not applicable | Completed | Anahuac Mayab University | 13 | 2022-08-01 | 2025-06-11 |
| Fruit & Vegetable Provision Study Fruit and vegetable provision - Food Security | Not applicable | Withdrawn | The University of Tennessee, Knoxville | 2022-06-14 | 2023-06-22 | |
| Fruit and Vegetable Rx (FVRx) + Home Plate Home Plate Lite, Home Plate, Fruit and Vegetable prescription - Food Insecurity | Not applicable | Completed | Children's Hospital of Philadelphia | 120 | 2022-01-01 | 2025-02-19 |
| Fruit and Vegetable Prescription in the Community Health Center Setting Fruit and Vegetable Prescription - Diabetes Mellitus, Diabetes Mellitus, Type 2 | Not applicable | Completed | Wholesome Wave | 200 | 2021-12-06 | 2024-02-23 |
| More Fresh Fruit and Vegetable Prescription Program for Families With Type 2 Diabetes Mellitus Fruit and Vegetable Prescription Voucher - Type 2 Diabetes | Not applicable | Recruiting | University of California, San Diego | 200 | 2021-11-29 | 2025-11-19 |
| Free Living Food Waste Management and Diet Quality Improvement Using Smart Intervention and Food Image Application Smart Intervention for Food Waste Management and Replacing current diet with Fruits and Vegetables, Smart Intervention for Stress Management - Diet, Healthy | Not applicable | Completed | Pennington Biomedical Research Center | 46 | 2021-08-23 | 2026-05-12 |
| Impacts of Fruit on the Gut Health and Human Health Fruit (2 cup eq), Fruit restriction (1/2 cup eq) - Cardiometabolic Health, Healthy Aging | Not applicable | Completed | San Diego State University | 40 | 2021-08-15 | 2025-01-08 |
| Assessment of a Fruit and Vegetable Prescription Program for Children Fruit and Vegetable Prescription - Exposure to Fruit and Vegetable Prescription Program | Not applicable | Completed | Michigan State University | 1400 | 2021-02-23 | 2025-10-16 |
| Evaluation of Increased Fruits and Vegetables Consumption in Chronic Kidney Disease Fruits and Vegetable increase - Chronic Kidney Diseases | Not applicable | Active not recruiting | Nand Wadhwa | 13 | 2020-11-24 | 2024-08-02 |
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Cardiovascular Diseases (8) · Obesity (7) · Hypertension (6) · Insulin Resistance (5) · Motor Activity (5) · Diabetes Mellitus, Type 2 (4) · Renal Insufficiency, Chronic (4) · Metabolic Syndrome (3) · Albuminuria (2) · Body Weight Changes (2) · Breast Neoplasms (2) · Diabetes Mellitus (2) · Inflammation (2) · Kidney Failure, Chronic (2) · Overweight (2)
Baylor Research Institute (2) · Donald Wesson (2) · Marjukka Kolehmainen (2) · University of California, San Francisco (2) · University of Leeds (2) · Academia Sinica, Taiwan (1) · Albert Einstein Healthcare Network (1) · Altria Client Services LLC (1) · Anahuac Mayab University (1) · Arizona State University (1) · Biofortis, Merieux NutriSciences (1) · Birmingham Community Healthcare NHS (1) · Centre Hospitalier Universitaire de la Réunion (1) · Children's Hospital of Philadelphia (1) · Cornell University (1)
United States (37) · United Kingdom (5) · Taiwan (4) · Canada (3) · Finland (3) · Sweden (3) · Australia (1) · China (1) · France (1) · Germany (1) · Mexico (1) · United Arab Emirates (1)
Ambria C Crusan, PhD (1) · Amy Saxe-Custack, PhD, MPH, RD (1) · Anne-Maria Pajari, PhD (1) · Atilio Canas, MD (1) · Bo-Han Wu (1) · Brent Bauer, MD (1) · Bruce P Barrett, MD, PhD (1) · Casey M. Rebholz, PhD, MS, MPH (1) · Chi-Chang Huang, PhD (1) · Corby K Martin, PhD (1) · Daivd JA Jenkins, MD, PhD (1) · Dean Schillinger, MD (1) · Devin J Rose, PhD (1) · Donald Wesson (1) · Donald Wesson, MD, MBA (1)
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U10CA081851 (2), K01DK107782 (1), K24AT006543 (1), R01DA046360 (1), R01HD102527 (1)