14 completed, 2 unknown, 1 suspended. 6 Not applicable, 6 Phase 4, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Unknown 1 |
| Phase 4 | 6 | Completed 4, Suspended 1, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow Felodipine: new trials by email Literature Review of Felodipine trials Research Report on Felodipine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Coronavirus (COVID-19) ACEi/ARB Investigation Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19 | Phase 4 | Suspended | National University of Ireland, Galway, Ireland | 2414 | 2020-04-30 | 2020-06-30 |
| ACEI or ARB and COVID-19 Severity and Mortality in US Veterans ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID | Completed | University of Utah | 22213 | 2020-01-19 | 2021-04-28 | |
| Copenhagen Acute Renal Complications After Transplantations Study Group Felodipine, Placebo - Disorder Related to Lung Transplantation | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 42 | 2013-09-01 | 2016-10-06 |
| Coffee Interaction With the Antihypertensive Drug Felodipine Black Coffee, Grapefruit Juice, Water - Food-Drug Interactions | Phase 1 | Completed | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 13 | 2012-02-01 | 2018-08-13 |
| China Medical University Hospital (CMUH) Triapin Listing Ramipril + Felodipine, Ramipril - Hypertension | Phase 4 | Completed | Sanofi | 49 | 2009-01-01 | 2010-08-27 |
| Evaluation of the Pharmacokinetic Interaction Between Candesartan and Felodipine After Ingestion of a Specific Meal Candesartan (test), Felodipine (test), Candesartan Cilexetil - Healthy | Phase 1 | Completed | AstraZeneca | 36 | 2008-10-01 | 2010-12-07 |
| Bioequivalence Study of Felodipine ER Tablets 10 mg Under Fed Conditions Felodipine, Felodipine (Plendil®) - Healthy | Not applicable | Completed | Ranbaxy Laboratories Limited | 80 | 2008-10-01 | 2014-12-08 |
| Bioequivalence Study of Felodipine ER Tablets 10 mg Under Fasting Conditions Felodipine, PLENDIL® - Healthy | Not applicable | Completed | Ranbaxy Laboratories Limited | 48 | 2008-09-01 | 2014-12-30 |
| Combined Antihypertensive Therapy and Sexual Dysfunction Felodipine add Irbesartan, Felodipine add Metoprolol - Hypertension, Sexual Dysfunction | Phase 4 | Unknown | LanZhou University | 280 | 2008-04-01 | 2010-11-11 |
| Role of AT1-receptor Blockers in Insulin-induced Vasodilation. Irbesartan, Felodipine, Placebo - Hypertension, Insulin Resistance | Not applicable | Unknown | Maastricht University Medical Center | 32 | 2008-03-01 | 2011-03-17 |
| Blood Pressure Lowering Effect of Transcutaneous Electrical Nerve Stimulation transcutaneous electrical nerve stimulation, felodipin - Hypertension | Not applicable | Completed | Sahlgrenska University Hospital | 41 | 2008-01-01 | 2011-07-11 |
| Candesartan Effectiveness Study in Pro-B Type Natriuretic Peptides (BNP) Candesartan, Felodipine - Hypertension, Left Ventricular Hypertrophy | Phase 4 | Completed | AstraZeneca | 315 | 2006-06-01 | 2012-04-02 |
| The Effects on Blood Pressure Control, Pulse Wave Velocity, as Well as Safety and Tolerability of Felodipine Sustained Release in Chinese Patients. Felodipine tablet (Plendil) alone, Felodipine tablet (Plendil)+Hydrochlorothiazide, Felodipine tablet (Plendil)+Metoprolol tablet (Betaloc ZOK) - Hypertension | Not applicable | Completed | AstraZeneca | 529 | 2005-12-01 | 2015-03-23 |
| Efficacy and Safety of Metoprolol Succinate Prolonged-Release Tablet in Patients With Mild to Moderate Hypertension metoprolol succinate prolonged-release tablet and felodipine - Hypertension | Phase 4 | Completed | AstraZeneca | 310 | 2005-10-01 | 2009-03-13 |
| Blood Pressure and Weight Trajectory on a Dual Antihypertensive Combination Plus Sibutramine Versus Placebo in Obese Hypertensives sibutramine, verapamil/trandolapril, metoprolol/HCT - Obesity, Hypertension | Phase 3 | Completed | Abbott | 171 | 2002-02-01 | 2008-05-19 |
| Action to Control Cardiovascular Risk in Diabetes (ACCORD) Anti-hyperglycemic Agents, Anti-hypertensive Agents, Blinded fenofibrate or placebo plus simvastatin - Atherosclerosis, Cardiovascular Diseases | Phase 3 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 10251 | 1999-09-01 | 2016-11-22 |
| Felodipine Event Reduction Study Felodipine, Placebo - Hypertension | Not applicable | Completed | Chinese Academy of Medical Sciences | 9800 | 1998-04-01 | 2010-06-25 |
Hypertension (12) · Cardiovascular Diseases (2) · Atherosclerosis (1) · COVID-19 (1) · Coronary Disease (1) · Coronavirus Infections (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Hypercholesterolemia (1) · Hypertrophy, Left Ventricular (1) · Insulin Resistance (1) · Obesity (1) · Renal Insufficiency, Chronic (1) · Sexual Dysfunction, Physiological (1)
AstraZeneca (4) · Ranbaxy Laboratories Limited (2) · Abbott (1) · Chinese Academy of Medical Sciences (1) · Copenhagen University Hospital, Rigshospitalet (1) · LanZhou University (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Maastricht University Medical Center (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · National University of Ireland, Galway, Ireland (1) · Sahlgrenska University Hospital (1) · Sanofi (1) · University of Utah (1)
Canada (2) · China (2) · United States (2) · Brazil (1) · Denmark (1) · Ireland (1) · Netherlands (1) · South Korea (1) · Sweden (1) · Taiwan (1)
Adam P Bress, PharmD, MS (1) · Bo Feldt-Rasmussen (1) · Clas Mannheimer, professor (1) · David G Bailey, BScPhm, PhD (1) · Denise Simons-Morton, MD, PhD (1) · Eduardo Abib Junior, MD (1) · Elisabet Stener-Victorin, ass.prof. (1) · Fern Lim (1) · Georgios Mourtzinis, MD (1) · JeeWoong Son, MD (1) · Jing Yu, Professor (1) · John William McEvoy, MBBCh MHS (1) · Jonas Silverdal, MD (1) · Karin Manhem, ass.prof. (1)
PMID 18539917, PMID 19898642, PMID 20061358, PMID 20061360, PMID 20215456, PMID 20228401, PMID 20228404, PMID 20427682, PMID 20571135, PMID 20587587, PMID 20594588, PMID 21345850, PMID 21366473, PMID 21663644, PMID 21958949, PMID 22019270, PMID 22049171, PMID 22134388, PMID 22179956, PMID 22374637, PMID 22432114, PMID 22450889, PMID 22515638, PMID 22619083, PMID 22646230, PMID 22723577, PMID 23033246, PMID 23238658, PMID 23412077, PMID 23990163, PMID 24170759, PMID 24296848, PMID 24493100, PMID 24595629, PMID 24779562, PMID 25088437, PMID 25127725, PMID 25159234, PMID 25172198, PMID 25193529, PMID 25229335, PMID 25267796, PMID 25652389, PMID 25666468, PMID 25887355, PMID 26261902, PMID 26459421, PMID 26464212, PMID 26476086, PMID 26822326
2008 (1), N01HC95178 (1), N01HC95179 (1), N01HC95180 (1), N01HC95181 (1), N01HC95182 (1), N01HC95183 (1), N01HC95184 (1)